{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T13:29:17Z","timestamp":1793971757638,"version":"4.8.0"},"reference-count":29,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T00:00:00Z","timestamp":1770681600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Clinical and Translational Research Project of Anhui Province","award":["202527c10020109"],"award-info":[{"award-number":["202527c10020109"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Perfusion"],"published-print":{"date-parts":[[2026,11]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>In China, Left Ventricular Assist Devices (LVADs) are increasingly adopted to improve the quality of life for patients with end-stage heart failure. This study aims to systematically present the clinical data and outcomes of LVAD implantations performed at Anhui Chest Hospital.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively analyzed 28 consecutive patients who underwent LVAD implantation from October 2024 to July 2025. Preoperative baselines were compared with 3-months postoperative outcomes, including Left Ventricular End-Diastolic Diameter (LVEDD), Ejection Fraction (LVEF), NYHA functional class, and 6-Minute Walk Distance (6MWD). Adverse events were recorded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      All 28 patients (20 males; mean age 59.7 \u00b1 12.3\u00a0years) successfully underwent the procedure. The postoperative ICU stay was 10 \u00b1 5.9\u00a0days. Complications within 90\u00a0days included hemorrhagic stroke (7%), malignant arrhythmia (3.5%), renal failure (3.5%), poor wound healing (3.5%), and one death (3.5%). No device malfunctions occurred. At 3 months, LVEDD significantly decreased (61.3 \u00b1 5.8 vs 75.2 \u00b1 9.4\u00a0mm), while LVEF (34.8 \u00b1 9.8% vs 22.7 \u00b1 5.6%) and 6MWD (356.1 \u00b1 159.4\u00a0m vs 85 \u00b1 49.6\u00a0m) significantly increased (all\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; 0.01). All surviving patients improved to NYHA class I\u2013II.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Preliminary results indicate that the application of Chinese LVADs demonstrates favorable clinical efficacy and acceptable safety profiles, serving as effective therapeutic strategies for advanced heart failure.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/02676591261426256","type":"journal-article","created":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T17:49:24Z","timestamp":1770745764000},"page":"1525-1533","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Left ventricular assist device therapy for advanced heart failure: A single-center retrospective study"],"prefix":"10.1177","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-5767-1572","authenticated-orcid":false,"given":"Liangliang","family":"Liu","sequence":"first","affiliation":[{"name":"Anhui Chest Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6861-9975","authenticated-orcid":false,"given":"Guiqing","family":"Liu","sequence":"additional","affiliation":[{"name":"Hammersmith Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Zhao","sequence":"additional","affiliation":[{"name":"Anhui Chest Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qikui","family":"Wang","sequence":"additional","affiliation":[{"name":"Anhui Chest Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Canmei","family":"Min","sequence":"additional","affiliation":[{"name":"Anhui Chest Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuhong","family":"Chen","sequence":"additional","affiliation":[{"name":"Anhui Chest Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengjie","family":"Shi","sequence":"additional","affiliation":[{"name":"Anhui Chest Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-9651-9179","authenticated-orcid":false,"given":"Liang","family":"Zhang","sequence":"additional","affiliation":[{"name":"Anhui Chest Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,2,10]]},"reference":[{"key":"e_1_3_6_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.1629"},{"key":"e_1_3_6_3_2","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2023.1192610"},{"key":"e_1_3_6_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/ehf2.14223"},{"key":"e_1_3_6_5_2","first-page":"e5617","article-title":"A rising hope of an artificial heart: left ventricular assisted device - outcome, convenience, and quality of life","volume":"11","author":"Thiha S","year":"2019","unstructured":"Thiha S, Zaidi ARZ, Robert CA, et al. A rising hope of an artificial heart: left ventricular assisted device - outcome, convenience, and quality of life. 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Reversibility of fixed pulmonary hypertension in left ventricular assist device support recipients. 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