{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T20:20:05Z","timestamp":1784233205277,"version":"3.55.0"},"reference-count":9,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T00:00:00Z","timestamp":1773100800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Perfusion"],"abstract":"<jats:p>\n                    Goal directed perfusion (GDP) aims to maintain an O\n                    <jats:sub>2<\/jats:sub>\n                    delivery above 270-300\u00a0ml\/min\/m\n                    <jats:sup>2<\/jats:sup>\n                    , during cardiopulmonary bypass. This strategy decreases the incidence of postoperative acute kidney injury. We first developed a simple physiological hypothesis that explained why maintaining an indexed DO\n                    <jats:sub>2<\/jats:sub>\n                    above 280-300\u00a0ml\/min\/m\n                    <jats:sup>2<\/jats:sup>\n                    could optimize organ protection during bypass, then we propose to tailor the O\n                    <jats:sub>2<\/jats:sub>\n                    supply to patient real time VO\n                    <jats:sub>2<\/jats:sub>\n                    as an individualized strategy, to optimize supply to metabolism need.\n                  <\/jats:p>","DOI":"10.1177\/02676591261433205","type":"journal-article","created":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T17:05:06Z","timestamp":1773248706000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Beyond goal directed perfusion: Individualizing O\n                    <sub>2<\/sub>\n                    -delivery to O\n                    <sub>2<\/sub>\n                    -consumption"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6846-8254","authenticated-orcid":false,"given":"Sylvain","family":"Diop","sequence":"first","affiliation":[{"name":"Marie Lannelongue Hospital"},{"name":"Marie Lannelongue Hospital"},{"name":"Marie Lannelongue Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-5257-3865","authenticated-orcid":false,"given":"Nicolas","family":"Mavambu","sequence":"additional","affiliation":[{"name":"Marie Lannelongue Hospital"},{"name":"Marie Lannelongue Hospital"},{"name":"Marie Lannelongue Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maxime","family":"Aparicio","sequence":"additional","affiliation":[{"name":"European Hospital Georges Pompidou"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoine","family":"Premachandra","sequence":"additional","affiliation":[{"name":"Marie Lannelongue Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacques","family":"Th\u00e8s","sequence":"additional","affiliation":[{"name":"Marie Lannelongue Hospital"},{"name":"Marie Lannelongue Hospital"},{"name":"Marie Lannelongue Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,3,10]]},"reference":[{"key":"e_1_3_4_2_2","first-page":"1918","article-title":"Goal-directed perfusion to reduce acute kidney injury: a randomized trial","volume":"156","author":"Ranucci M","year":"2018","unstructured":"Ranucci M, Johnson I, Willcox T, et al. Goal-directed perfusion to reduce acute kidney injury: a randomized trial. JTCVS 2018; 156: 1918\u20131927. https:\/\/doi.org\/10.1016\/j.jtcvs.2018.04.045","journal-title":"JTCVS"},{"key":"e_1_3_4_3_2","first-page":"750","article-title":"Oxygen delivery-guided perfusion for the prevention of acute kidney injury: a randomized controlled trial","volume":"165","author":"Hiroshi M","year":"2021","unstructured":"Hiroshi M, Matsushita S, Yamamoto T, et al. Oxygen delivery-guided perfusion for the prevention of acute kidney injury: a randomized controlled trial. JTCVS 2021; 165: 750\u2013760.","journal-title":"JTCVS"},{"key":"e_1_3_4_4_2","first-page":"331","article-title":"Resting oxygen uptake value of 1 metabolic equivalent of task in older adults: a systematic review and descriptive analysis","volume":"52","author":"Leal-Mart\u00edn J","year":"2022","unstructured":"Leal-Mart\u00edn J, Mu\u00f1oz-Mu\u00f1oz M, Keadle SK, et al. Resting oxygen uptake value of 1 metabolic equivalent of task in older adults: a systematic review and descriptive analysis. Sports 2022; 52: 331\u2013348. https:\/\/doi.org\/10.1007\/s40279-021-01539-1","journal-title":"Sports"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpc.2008.12.009"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1089\/ham.2007.1079"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/aas.13265"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.jvca.2024.09.013"},{"key":"e_1_3_4_9_2","first-page":"903","article-title":"Whole-body oxygen consumption during low-flow hypothermic cardiopulmonary bypass","volume":"86","author":"Hickey RF","year":"1983","unstructured":"Hickey RF, Paul FH. Whole-body oxygen consumption during low-flow hypothermic cardiopulmonary bypass. JTCVS 1983; 86: 903\u2013906.","journal-title":"JTCVS"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1186\/cc10349"}],"container-title":["Perfusion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02676591261433205","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/02676591261433205","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02676591261433205","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T17:37:00Z","timestamp":1777657020000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/02676591261433205"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,10]]},"references-count":9,"alternative-id":["10.1177\/02676591261433205"],"URL":"https:\/\/doi.org\/10.1177\/02676591261433205","relation":{},"ISSN":["0267-6591","1477-111X"],"issn-type":[{"value":"0267-6591","type":"print"},{"value":"1477-111X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,10]]},"article-number":"02676591261433205"}}