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We report a case of a 33\u00a0year old male with WAS who underwent a redo ascending aorta and total aortic arch replacement as part of a two stage surgery for a Type B aortic dissection. The report discusses the considerations given to cardiopulmonary bypass in order to mitigate platelet number reduction and the degree of systemic inflammatory response. Post operative viscoelastometry indicated a minor hypocoagulopathy with minimal post-operative bleeding.<\/jats:p>","DOI":"10.1177\/02676591261461645","type":"journal-article","created":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T20:17:44Z","timestamp":1781122664000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Redo ascending aorta and total arch replacement in patient with Wiskott-Aldrich syndrome: A case report"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-0529-0472","authenticated-orcid":false,"given":"Naoise","family":"\u00d3 Ciardha","sequence":"first","affiliation":[{"name":"Royal Infirmary of Edinburgh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincenzo","family":"Giordano","sequence":"additional","affiliation":[{"name":"Royal Infirmary of Edinburgh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Stagg","sequence":"additional","affiliation":[{"name":"Royal Infirmary of Edinburgh"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,6,10]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10875-017-0453-z"},{"key":"e_1_3_3_3_2","unstructured":"National Library of Medicine - Medline Plus. 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