{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T17:40:37Z","timestamp":1777916437349,"version":"3.51.4"},"reference-count":42,"publisher":"SAGE Publications","issue":"1_suppl","license":[{"start":{"date-parts":[[2016,2,25]],"date-time":"2016-02-25T00:00:00Z","timestamp":1456358400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Phlebology"],"published-print":{"date-parts":[[2016,3]]},"abstract":"<jats:p>Compression therapy, prescribed as elastic compression stockings, is the cornerstone in the management of post-thrombotic syndrome. The effectiveness of elastic compression stockings has recently been called into question in a large randomized placebo-controlled trial. The findings however may be less contradictory than assumed and presented. The mechanistic substrate for the effectiveness of compression therapy is based on its ability to counteract venous hypertension, which is a central aspect in the pathophysiology of post-thrombotic syndrome. Nevertheless, despite elastic compression stockings a significant percentage (20\u201350%) of patients develops post-thrombotic syndrome, suggesting that there are other factors to be considered next to compression. Every patient has an individual baseline risk value, constituted of non-modifiable and modifiable risk factors (i.e. age, sex, bodyweight etcetera). Straining patients at risk is therefore crucial. Exploring additional or alternative forms of therapy is desirable as well since these are in addition to the risk factors, costs aspects and quality of life, puzzle pieces in the management of post-thrombotic syndrome, which once pieced together enables multifactorial yet individualized therapy.<\/jats:p>","DOI":"10.1177\/0268355516632986","type":"journal-article","created":{"date-parts":[[2016,2,25]],"date-time":"2016-02-25T06:52:41Z","timestamp":1456383161000},"page":"41-47","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["Compression to prevent PTS: a controversy?"],"prefix":"10.1177","volume":"31","author":[{"given":"Elham","family":"Amin","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Maastricht University Medical Centre, Maastricht, The Netherlands"},{"name":"KEMTA, Maastricht University Medical Centre, Maastricht, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuela A","family":"Joore","sequence":"additional","affiliation":[{"name":"KEMTA, Maastricht University Medical Centre, Maastricht, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arina J","family":"ten Cate-Hoek","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Maastricht University Medical Centre, Maastricht, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2016,2,25]]},"reference":[{"key":"bibr1-0268355516632986","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-125-1-199607010-00001"},{"key":"bibr2-0268355516632986","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(96)12215-7"},{"key":"bibr3-0268355516632986","doi-asserted-by":"publisher","DOI":"10.1378\/chest.08-0658"},{"key":"bibr4-0268355516632986","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)61902-9"},{"key":"bibr5-0268355516632986","doi-asserted-by":"crossref","unstructured":"Perrin M and Ekl\u00f6f B. Does prescription of medical compression prevent development of post-thrombotic syndrome after proximal deep venous thrombosis?\n                      Phlebology\n                      . Epub ahead of print May 2015. DOI: 10.1177\/0268355515585437.","DOI":"10.1177\/0268355515585437"},{"key":"bibr6-0268355516632986","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2007.02.034"},{"key":"bibr7-0268355516632986","first-page":"127","volume":"23","author":"Stewart GJ","year":"1993","journal-title":"Haemostasis"},{"key":"bibr8-0268355516632986","doi-asserted-by":"publisher","DOI":"10.1016\/S0741-5214(03)00431-2"},{"key":"bibr9-0268355516632986","doi-asserted-by":"publisher","DOI":"10.1097\/MBC.0b013e328011f2dd"},{"key":"bibr10-0268355516632986","doi-asserted-by":"crossref","unstructured":"Ten Cate-Hoek AJ, Henke PK and Wakefield TW. The post thrombotic syndrome: Ignore it and it will come back to bite you.\n                      Blood Rev\n                      . Epub ahead of print October 2015. DOI: 10.1016\/j.blre.2015.09.002.","DOI":"10.1016\/j.blre.2015.09.002"},{"key":"bibr11-0268355516632986","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.161.17.2105"},{"key":"bibr12-0268355516632986","first-page":"A8726","volume":"159","author":"ten Cate-Hoek AJ","year":"2015","journal-title":"Ned Tijdschr Geneeskd"},{"key":"bibr13-0268355516632986","doi-asserted-by":"publisher","DOI":"10.1016\/j.thromres.2012.01.004"},{"key":"bibr14-0268355516632986","doi-asserted-by":"publisher","DOI":"10.1177\/0268355514528131"},{"key":"bibr15-0268355516632986","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2014-005265"},{"key":"bibr16-0268355516632986","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2008.03180.x"},{"key":"bibr17-0268355516632986","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-149-10-200811180-00004"},{"key":"bibr18-0268355516632986","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2010.01.089"},{"key":"bibr19-0268355516632986","doi-asserted-by":"publisher","DOI":"10.1055\/s-0037-1613447"},{"key":"bibr20-0268355516632986","doi-asserted-by":"publisher","DOI":"10.1097\/MOH.0b013e3283634443"},{"key":"bibr21-0268355516632986","doi-asserted-by":"publisher","DOI":"10.1016\/j.thromres.2015.05.019"},{"key":"bibr22-0268355516632986","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2005.01648.x"},{"key":"bibr23-0268355516632986","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.080493"},{"key":"bibr24-0268355516632986","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2010.04001.x"},{"key":"bibr25-0268355516632986","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2012.04798.x"},{"key":"bibr26-0268355516632986","doi-asserted-by":"publisher","DOI":"10.1016\/j.thromres.2015.06.024"},{"key":"bibr27-0268355516632986","doi-asserted-by":"publisher","DOI":"10.1007\/s11239-006-9010-y"},{"key":"bibr28-0268355516632986","doi-asserted-by":"publisher","DOI":"10.1097\/JSM.0b013e3181bd11a3"},{"key":"bibr29-0268355516632986","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2003.09.036"},{"key":"bibr30-0268355516632986","doi-asserted-by":"publisher","DOI":"10.1046\/j.1538-7836.2003.00092.x"},{"key":"bibr31-0268355516632986","first-page":"623","volume":"99","author":"O'Donnell MJ","year":"2008","journal-title":"A randomized controlled trial. Thromb Haemost"},{"key":"bibr32-0268355516632986","doi-asserted-by":"publisher","DOI":"10.1177\/1358863X14521883"},{"key":"bibr33-0268355516632986","doi-asserted-by":"publisher","DOI":"10.1055\/s-0038-1651011"},{"key":"bibr34-0268355516632986","first-page":"13","volume":"53","author":"Ippolito E","year":"2011","journal-title":"Panminerva Med"},{"key":"bibr35-0268355516632986","doi-asserted-by":"publisher","DOI":"10.2174\/1570161052773870"},{"key":"bibr36-0268355516632986","doi-asserted-by":"publisher","DOI":"10.1177\/1076029614533143"},{"key":"bibr37-0268355516632986","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2008.12.023"},{"key":"bibr38-0268355516632986","doi-asserted-by":"publisher","DOI":"10.1007\/s11239-012-0687-9"},{"key":"bibr39-0268355516632986","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.165.10.1173"},{"key":"bibr40-0268355516632986","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-126-6-199703150-00006"},{"key":"bibr41-0268355516632986","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-4733.2003.00204.x"},{"key":"bibr42-0268355516632986","doi-asserted-by":"publisher","DOI":"10.1016\/j.thromres.2005.12.005"}],"container-title":["Phlebology: The Journal of Venous Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0268355516632986","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0268355516632986","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0268355516632986","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T17:48:02Z","timestamp":1777657682000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0268355516632986"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,2,25]]},"references-count":42,"journal-issue":{"issue":"1_suppl","published-print":{"date-parts":[[2016,3]]}},"alternative-id":["10.1177\/0268355516632986"],"URL":"https:\/\/doi.org\/10.1177\/0268355516632986","relation":{},"ISSN":["0268-3555","1758-1125"],"issn-type":[{"value":"0268-3555","type":"print"},{"value":"1758-1125","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,2,25]]}}}