{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T17:42:03Z","timestamp":1777916523918,"version":"3.51.4"},"reference-count":29,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2018,5,31]],"date-time":"2018-05-31T00:00:00Z","timestamp":1527724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Scandinavian research foundation for venous diseases"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Phlebology"],"published-print":{"date-parts":[[2019,4]]},"abstract":"<jats:sec>\n                    <jats:title>Background\/aim<\/jats:title>\n                    <jats:p>Mesenteric venous thrombosis is a rare lethal disease. The main aim of the present study was to evaluate clinical efficacy and safety of direct oral anticoagulants and vitamin K antagonists in mesenteric venous thrombosis patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Retrospective study of 102 mesenteric venous thrombosis patients treated between 2004 and 2017 at a center with a conservative medical first approach. Median clinical follow-up was 4 years.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Computed tomography showed successful recanalization of thrombosis in 71% of patients on vitamin K antagonists and 69% of patients on direct oral anticoagulants ( p\u2009=\u20090.88). Overall major and esophageal variceal bleeding rate was 14.7% and 2.9%, respectively. No difference in major bleeding ( p\u2009=\u20090.54) was found between vitamin K antagonists and direct oral anticoagulants. No mesenteric venous thrombosis recurrence occurred during follow-up, and one venous thromboembolism occurred after cessation of anticoagulation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Anticoagulation with direct oral anticoagulants and vitamin K antagonists was efficient in patients with mesenteric venous thrombosis. Bleeding complications was a concern during treatment in both groups.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0268355518779517","type":"journal-article","created":{"date-parts":[[2018,5,31]],"date-time":"2018-05-31T04:50:33Z","timestamp":1527742233000},"page":"171-178","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":20,"title":["Evaluation of direct oral anticoagulants and vitamin K antagonists in mesenteric venous thrombosis"],"prefix":"10.1177","volume":"34","author":[{"given":"Saman","family":"Salim","sequence":"first","affiliation":[{"name":"Department of Clinical Sciences, Malm\u00f6, Lund University, Malm\u00f6, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olle","family":"Ekberg","sequence":"additional","affiliation":[{"name":"Department of Translational Medicine, Division of Medical Radiology, Lund University, Malm\u00f6, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johan","family":"Elf","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, Malm\u00f6, Lund University, Malm\u00f6, Sweden"},{"name":"Vascular Centre, Department of Cardio-Thoracic and Vascular Surgery, Sk\u00e5ne University Hospital, Malm\u00f6, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Moncef","family":"Zarrouk","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, Malm\u00f6, Lund University, Malm\u00f6, Sweden"},{"name":"Vascular Centre, Department of Cardio-Thoracic and Vascular Surgery, Sk\u00e5ne University Hospital, Malm\u00f6, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anders","family":"Gotts\u00e4ter","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, Malm\u00f6, Lund University, Malm\u00f6, Sweden"},{"name":"Vascular Centre, Department of Cardio-Thoracic and Vascular Surgery, Sk\u00e5ne University Hospital, Malm\u00f6, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3225-0798","authenticated-orcid":false,"given":"Stefan","family":"Acosta","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, Malm\u00f6, Lund University, Malm\u00f6, Sweden"},{"name":"Vascular Centre, Department of Cardio-Thoracic and Vascular Surgery, Sk\u00e5ne University Hospital, Malm\u00f6, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2018,5,31]]},"reference":[{"key":"bibr1-0268355518779517","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2017.01.010"},{"key":"bibr2-0268355518779517","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpg.2016.11.002"},{"key":"bibr3-0268355518779517","doi-asserted-by":"publisher","DOI":"10.1053\/j.tvir.2014.12.002"},{"key":"bibr4-0268355518779517","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvsv.2016.04.002"},{"key":"bibr5-0268355518779517","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.6319"},{"key":"bibr6-0268355518779517","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.114.012871"},{"key":"bibr7-0268355518779517","doi-asserted-by":"publisher","DOI":"10.1097\/CRD.0b013e3182503e2d"},{"key":"bibr8-0268355518779517","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2015.11.026"},{"key":"bibr9-0268355518779517","doi-asserted-by":"publisher","DOI":"10.1007\/s11239-015-1308-1"},{"key":"bibr10-0268355518779517","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0906598"},{"key":"bibr11-0268355518779517","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1007903"},{"key":"bibr12-0268355518779517","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1306638"},{"key":"bibr13-0268355518779517","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1302507"},{"key":"bibr14-0268355518779517","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1113572"},{"key":"bibr15-0268355518779517","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehr134"},{"key":"bibr16-0268355518779517","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2009.03678.x"},{"key":"bibr17-0268355518779517","doi-asserted-by":"publisher","DOI":"10.1373\/clinchem.2005.051557"},{"key":"bibr18-0268355518779517","doi-asserted-by":"publisher","DOI":"10.1007\/s10140-009-0807-9"},{"key":"bibr19-0268355518779517","doi-asserted-by":"publisher","DOI":"10.1016\/j.thromres.2015.04.016"},{"key":"bibr20-0268355518779517","doi-asserted-by":"publisher","DOI":"10.1038\/bcj.2016.103"},{"key":"bibr21-0268355518779517","doi-asserted-by":"publisher","DOI":"10.1160\/TH08-12-0842"},{"key":"bibr22-0268355518779517","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2014-07-551515"},{"key":"bibr23-0268355518779517","doi-asserted-by":"crossref","unstructured":"Nagaoki Y, Aikata H, Daijyo K, et\u00a0al. 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