{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T14:31:10Z","timestamp":1791815470016,"version":"4.3.4"},"reference-count":36,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2019,6,24]],"date-time":"2019-06-24T00:00:00Z","timestamp":1561334400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Phlebology"],"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Compression therapy by inelastic bandages is highly effective in achieving venous leg ulcer healing. Inelastic bandages may be expensive as they need to be changed and discarded at every dressing change. In addition, correct application is difficult in the clinical practice, even by expert healthcare personnel. The aim of our work was to assess whether adjustable compression wraps are more cost effective and more effective than inelastic bandage to achieve venous leg ulcer healing.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Sixty-six venous leg ulcer patients were randomized to be treated by adjustable compression wrap (CircAid\u00ae JuxtaCure\u00ae) ( n\u2009=\u200933) and inelastic bandage (Coban 2 Layer\u00ae) ( n\u2009=\u200933). Study duration was 12\u00a0weeks. During weekly visits, the ulcers were cleansed and dressed with the same products, and the only variable was the compression device. Ulcer size, ulcer pain, patient\u2019s perception of compression systems, and compression pressure were assessed during the visits, and the material cost was evaluated at the 12th week.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Adjustable compression wraps were significantly cheaper than bandages (p\u2009&lt;\u20090.0001) and were also more effective (not significantly) in achieving ulcer healing. To heal one ulcer patient, \u20ac228 had to be spent when applying an adjustable compression wrap and \u20ac381 if inelastic bandages were used. About 26\/33 (78.8%) patients in the adjustable compression wrap group were healed after 12\u00a0weeks versus 23\/33 (69.7%) in the inelastic bandage group (n.s.). Ulcer pain was reduced by both compression devices. Patient perception of compression pressure was similar with both compression devices. Compression pressure was similar at application but better maintained by adjustable compression wrap over time.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Adjustable compression wraps are significantly cheaper and more effective (not significantly) in achieving venous leg ulcer healing. Self-applicable, adjustable compression wraps are therefore a powerful, cost-effective alternative to inelastic bandages in treating venous leg ulcer.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0268355519858439","type":"journal-article","created":{"date-parts":[[2019,6,25]],"date-time":"2019-06-25T10:02:13Z","timestamp":1561456933000},"page":"124-133","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":54,"title":["Adjustable compression wrap devices are cheaper and more effective than inelastic bandages for venous leg ulcer healing. A Multicentric Italian Randomized Clinical Experience"],"prefix":"10.1177","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7639-8463","authenticated-orcid":false,"given":"Giovanni","family":"Mosti","sequence":"first","affiliation":[{"name":"Angiology Department, MD Barbantini Clinic, Lucca, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Mancini","sequence":"additional","affiliation":[{"name":"Heart and Vascular Surgery Department, University of Siena, Siena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio","family":"Bruni","sequence":"additional","affiliation":[{"name":"Outpatient Department for Hard-to-Heal skin ulcers, San Giuseppe Hospital, Empoli, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simone","family":"Serantoni","sequence":"additional","affiliation":[{"name":"Vascular Ulcers and Diabetic Foot Surgery Unit, Villa Fiorita Clinic, Prato, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Gazzabin","sequence":"additional","affiliation":[{"name":"Vascular Ulcers and Diabetic Foot Surgery Unit, Villa Fiorita Clinic, Prato, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matteo","family":"Bucalossi","sequence":"additional","affiliation":[{"name":"Surgery Department, Valdisieve Hospital, Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Polignano","sequence":"additional","affiliation":[{"name":"Vascular Medicine Dpt. USL Toscana Centro, Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabrizio","family":"Mariani","sequence":"additional","affiliation":[{"name":"Angiomedica Clinic, Colle di Val d\u2019Elsa, Siena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bastiani","family":"Luca","sequence":"additional","affiliation":[{"name":"Institute of Clinical Physiology, Italian National Research Council e CNR, Pisa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9476-7381","authenticated-orcid":false,"given":"Hugo","family":"Partsch","sequence":"additional","affiliation":[{"name":"Emeritus, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"The MIRACLE Trial investigators","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2019,6,24]]},"reference":[{"key":"bibr1-0268355519858439","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2014.04.049"},{"key":"bibr2-0268355519858439","first-page":"202","volume":"34","author":"Mosti G","year":"2015","journal-title":"Int Angiol"},{"key":"bibr3-0268355519858439","doi-asserted-by":"publisher","DOI":"10.12968\/jowc.2016.25.Sup6.S1"},{"key":"bibr4-0268355519858439","doi-asserted-by":"publisher","DOI":"10.1111\/wrr.12394"},{"key":"bibr5-0268355519858439","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2015.02.007"},{"issue":"3","key":"bibr6-0268355519858439","doi-asserted-by":"crossref","first-page":"181","DOI":"10.23736\/S0392-9590.18.03999-8","volume":"37","author":"Nicolaides A","year":"2018","journal-title":"Int Angiol"},{"key":"bibr7-0268355519858439","unstructured":"Macci\u00f2 A, Mancini S, Bucalossi Met\u00a0al. Compression Therapy and Wound Healing. In: Mariani F (ed.)\n                      Consensus conference on compression therapy\n                      . 3rd ed. Airali, Siena, 2018, pp.141\u2013151."},{"key":"bibr8-0268355519858439","first-page":"794","volume":"12","author":"Protz K","year":"2014","journal-title":"JDDG"},{"key":"bibr9-0268355519858439","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-481X.2009.00621.x"},{"key":"bibr10-0268355519858439","first-page":"181","volume":"4","author":"Nelson EA","year":"1995","journal-title":"JWC"},{"key":"bibr11-0268355519858439","first-page":"55","volume":"8","author":"Reynolds S.","year":"1985","journal-title":"JWC"},{"key":"bibr12-0268355519858439","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2013.7962"},{"key":"bibr13-0268355519858439","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2010.04.081"},{"key":"bibr14-0268355519858439","doi-asserted-by":"publisher","DOI":"10.4081\/vl.2017.7003"},{"key":"bibr15-0268355519858439","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvsv.2012.05.001"},{"key":"bibr16-0268355519858439","first-page":"600","volume":"34","author":"Partsch H","year":"2008","journal-title":"Dermatol Surg"},{"key":"bibr17-0268355519858439","unstructured":"www.tagungsmanagement.org\/comp\/images\/PDF\/icc_questionnaire\/manual_icc_compression_questionnaire.pdf (accessed 12 June 2019)."},{"key":"bibr18-0268355519858439","first-page":"426","volume":"29","author":"Partsch H","year":"2010","journal-title":"Int Angiol"},{"key":"bibr19-0268355519858439","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2006.32039.x"},{"key":"bibr20-0268355519858439","doi-asserted-by":"publisher","DOI":"10.1097\/00042728-200506000-00002"},{"key":"bibr21-0268355519858439","doi-asserted-by":"publisher","DOI":"10.12968\/jowc.2017.26.5.244"},{"key":"bibr22-0268355519858439","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-481X.2008.00487.x"},{"key":"bibr23-0268355519858439","first-page":"126","volume":"5","author":"Mosti G","year":"2011","journal-title":"Wounds"},{"key":"bibr24-0268355519858439","doi-asserted-by":"publisher","DOI":"10.12968\/jowc.2016.25.5.242"},{"key":"bibr25-0268355519858439","doi-asserted-by":"publisher","DOI":"10.12968\/bjcn.2013.18.Sup6.S34"},{"key":"bibr26-0268355519858439","first-page":"25","volume":"29","author":"Elvin S.","year":"2015","journal-title":"J Commun Nurs"},{"key":"bibr27-0268355519858439","first-page":"S42","volume":"40","author":"Nugent L.","year":"2013","journal-title":"Br J Commun Nurs"},{"key":"bibr28-0268355519858439","unstructured":"The Juxta CURES adjustable compression system for treating venous leg ulcers. 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