{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T14:31:10Z","timestamp":1791815470877,"version":"4.3.4"},"reference-count":22,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2021,1,12]],"date-time":"2021-01-12T00:00:00Z","timestamp":1610409600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Medi UK"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Phlebology"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>The mainstay of treatment for venous ulceration remains compression therapy. Velcro Wrap devices are being increasingly used in these patients despite limited evidence. This feasibility study aimed to compare standard bandaging to the JuxtaCures\u2122 Velcro wrap device.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A single centre, unblinded RCT compared participants with venous ulceration randomised to either the JuxtaCures\u2122 device or short stretch bandaging. Participants were followed up for 26\u2009weeks.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      160 participants were screened with 40 randomised. 3 participants in bandaging and 1 in JuxtaCures\u2122 didn\u2019t complete the study. 60% in JuxtaCures\u2122 healed v 55% in bandaging despite larger ulcers in the JuxtaCures\u2122 arm (9.33\u2009cm\n                      <jats:sup>2<\/jats:sup>\n                      v 6.97\u2009cm\n                      <jats:sup>2<\/jats:sup>\n                      ). There was no significant difference in time to healing (12.17 v 13.64 weeks). JuxtaCures\u2122 showed improved ulcer reduction for those that didn\u2019t heal (14.91\u20135.00\u2009cm\n                      <jats:sup>2<\/jats:sup>\n                      v 14.20\u20138.62\u2009cm\n                      <jats:sup>2<\/jats:sup>\n                      ; P\u2009=\u20090.06). JuxtaCures\u2122 had more consistent sub-bandage pressure dropping from 39\u201336\u2009mmHg versus 41\u201325\u2009mmHg in bandaging between application and removal (P\u2009&lt;\u20090.001). Quality of life (EQ5D) was improved in JuxtaCures at 3\u2009months (mean difference 0.14, p\u2009=\u20090.04), but not at 1 and 6\u2009months, or in disease specific quality of life. Cost was lower in JuxtaCures\u2122 \u00a3842.47 v \u00a31064.68. Duration of appointment was significantly shorter in JuxtaCures\u2122 (41\u2009minutes v 53\u2009minutes; P\u2009=\u20090.003).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study has shown the feasibility and necessity of running a multicentre trial to evaluate the use of Velcro wrap devices for venous ulceration. It highlights the potential benefits of more consistent pressure, increased self-care, and potential with regards to ulcer healing, cost, nursing resource and quality of life.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0268355520988226","type":"journal-article","created":{"date-parts":[[2021,1,14]],"date-time":"2021-01-14T21:29:54Z","timestamp":1610659794000},"page":"505-514","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":12,"title":["A randomised controlled clinical trial comparing the effectiveness of bandaging compared to the JuxtaCures\u2122 device in the management of people with venous ulceration: Feasibility study"],"prefix":"10.1177","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3585-6728","authenticated-orcid":false,"given":"Philip","family":"Stather","sequence":"first","affiliation":[{"name":"East Suffolk North Essex Foundation Trust, Colchester Hospital, Colchester, UK"},{"name":"Norfolk and Norwich University Hospital, Norwich, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carroll","family":"Petty","sequence":"additional","affiliation":[{"name":"East Suffolk North Essex Foundation Trust, Colchester Hospital, Colchester, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helen","family":"Langthorne","sequence":"additional","affiliation":[{"name":"East Suffolk North Essex Foundation Trust, Colchester Hospital, Colchester, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emma","family":"Rayner","sequence":"additional","affiliation":[{"name":"East Suffolk North Essex Foundation Trust, Colchester Hospital, Colchester, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jufen","family":"Zhang","sequence":"additional","affiliation":[{"name":"Clinical Trial Unit, School of Medicine, Anglia Ruskin University, Chelmsford, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4223-0659","authenticated-orcid":false,"given":"Karen","family":"Hayden","sequence":"additional","affiliation":[{"name":"Clinical Trial Unit, School of Medicine, Anglia Ruskin University, Chelmsford, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam","family":"Howard","sequence":"additional","affiliation":[{"name":"East Suffolk North Essex Foundation Trust, Colchester Hospital, Colchester, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,1,12]]},"reference":[{"key":"bibr1-0268355520988226","doi-asserted-by":"publisher","DOI":"10.1053\/j.semvascsurg.2015.05.002"},{"key":"bibr2-0268355520988226","unstructured":"Scottish Intercollegiate Guidelines Network (SIGN). 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