{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T17:43:40Z","timestamp":1777916620929,"version":"3.51.4"},"reference-count":26,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2022,3,24]],"date-time":"2022-03-24T00:00:00Z","timestamp":1648080000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Phlebology"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To compare the use of biological autologous excised varicose vein dressing ( VenoDress) compared to conservative dressing on the ulcer bed during endovenous ablation<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective non-blinded study included all consecutive patients with primary or recurrent venous leg ulcers (VLU) with superficial varices treated in one center between September 2019 and October 2020. They all underwent venous ablation, wound debridement, and when needed phlebectomy. On the study group, the excised veins were incised, formed into a sheet, and applied onto the debrided wound bed with the endothelial side facing the wound bed. Adhesion was assessed weekly for 3\u00a0weeks. The study group was compared to a control group that underwent similar procedures but with the debrided wound bed treated with low-adherent paraffin dressing. The primary outcome was complete wound healing at 1 and 3 months, and the secondary outcomes were wound-related pain and leg edema.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Complete wound closure was documented in 17\/26 study group patients at 1\u00a0month (65%) and in 25\/26 (96%) at 3\u00a0months. Complete wound closure was documented in 37\/82 patients in the control group (45%) and in 67\/82 (82%) at 3\u00a0months. The 1-month healing rates were significantly in favor of the VenoDress group when adjusted to sex and diabetes: odds ratio = 2.81 (1.05\u20137.532), p = .04. The preoperative pain level of the study group (as measured by a visual analog scale VAS (0\u201310) decreased from 4.96 \u00b1 2.71 to 0.73 \u00b1 1.36 at 1\u00a0week and that of the control group from 4.8 \u00b1 2 to 1.35 \u00b1 1.38 at 1\u00a0week ( p &lt; .001).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>the use of autologous varicose veins as dressing effectively reduced pain in VLU patients compared to conventional techniques. Although its effects on wound closure appear highly promising, further validation is warranted in a randomized comparative study.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/02683555221081635","type":"journal-article","created":{"date-parts":[[2022,3,24]],"date-time":"2022-03-24T22:23:17Z","timestamp":1648160597000},"page":"386-392","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Biological autologous excised varicose vein dressing compared to conservative dressing on the ulcer bed during endovenous ablation"],"prefix":"10.1177","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9050-5608","authenticated-orcid":false,"given":"Ram","family":"Avrahami","sequence":"first","affiliation":[{"name":"T. L. M. Medical Center, Tel-Aviv, Israel"},{"name":"Department of Vascular Surgery, Rabin Medical Center, Petach Tikva, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Silverberg","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, the Chaim Sheba Medical Center, Tel Hashomer, Israel"},{"name":"Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ralph","family":"Kolvenbach","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery and Endovascular Therapy, SANA Hospital Group, D\u00fcsseldorf, Germany"},{"name":"Academic Teaching Hospital, Heinrich Heine University of D\u00fcsseldorf, D\u00fcsseldorf, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven","family":"Elias","sequence":"additional","affiliation":[{"name":"Center for Vein Disease, Englewood Health Network, Englewood, NJ, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Galit","family":"Sivak","sequence":"additional","affiliation":[{"name":"T. L. M. Medical Center, Tel-Aviv, Israel"},{"name":"Department of Vascular Surgery, Rabin Medical Center, Petach Tikva, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,3,24]]},"reference":[{"key":"bibr1-02683555221081635","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1615243"},{"key":"bibr2-02683555221081635","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/413604"},{"key":"bibr3-02683555221081635","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvsv.2014.04.006"},{"key":"bibr4-02683555221081635","doi-asserted-by":"publisher","DOI":"10.1053\/ejvs.2000.1157"},{"key":"bibr5-02683555221081635","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1801214"},{"key":"bibr6-02683555221081635","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2004.10.002"},{"key":"bibr7-02683555221081635","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39216.542442"},{"key":"bibr8-02683555221081635","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10010029"},{"key":"bibr9-02683555221081635","doi-asserted-by":"publisher","DOI":"10.1186\/s41038-019-0148-1"},{"key":"bibr10-02683555221081635","doi-asserted-by":"publisher","DOI":"10.1111\/wrr.12205"},{"key":"bibr11-02683555221081635","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD012583.pub2"},{"key":"bibr12-02683555221081635","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2019.06.024"},{"key":"bibr13-02683555221081635","doi-asserted-by":"publisher","DOI":"10.1016\/S0741-5214(98)70141-7"},{"key":"bibr14-02683555221081635","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2003.12.015"},{"key":"bibr15-02683555221081635","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2004.12.044"},{"key":"bibr16-02683555221081635","doi-asserted-by":"publisher","DOI":"10.1016\/j.avsg.2019.01.025"},{"key":"bibr17-02683555221081635","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-005-1044-x"},{"key":"bibr18-02683555221081635","doi-asserted-by":"publisher","DOI":"10.3121\/cmr.2009.819"},{"key":"bibr19-02683555221081635","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvsv.2020.01.006"},{"key":"bibr20-02683555221081635","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvsv.2019.09.016"},{"key":"bibr21-02683555221081635","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvsv.2020.01.014"},{"key":"bibr22-02683555221081635","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2006.12.037"},{"key":"bibr23-02683555221081635","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvsv.2017.02.007"},{"key":"bibr24-02683555221081635","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD001737.pub4"},{"issue":"4","key":"bibr25-02683555221081635","first-page":"253","volume":"16","author":"Hermanns HJ","year":"2009","journal-title":"Phlebolymphology"},{"key":"bibr26-02683555221081635","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/582080"}],"container-title":["Phlebology: The Journal of Venous Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02683555221081635","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/02683555221081635","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02683555221081635","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T17:52:50Z","timestamp":1777657970000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/02683555221081635"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,24]]},"references-count":26,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,6]]}},"alternative-id":["10.1177\/02683555221081635"],"URL":"https:\/\/doi.org\/10.1177\/02683555221081635","relation":{},"ISSN":["0268-3555","1758-1125"],"issn-type":[{"value":"0268-3555","type":"print"},{"value":"1758-1125","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,24]]}}}