{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T00:12:38Z","timestamp":1782951158994,"version":"3.54.5"},"reference-count":16,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2022,9,26]],"date-time":"2022-09-26T00:00:00Z","timestamp":1664150400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Phlebology"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Exercise improves haemodynamic parameters in patients with chronic venous disease. There is a paucity of evidence on its effect in post-thrombotic syndrome (PTS). The aim of this systematic review is to assess the impact of exercise in PTS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Adhering to PRISMA guidelines and following PROSPERO registration (CRD42021220924), MEDLINE, Cochrane Library, EMBASE database, and trial registries were searched on 19th May 2022.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>One article met the inclusion criteria and a narrative synthesis was carried out. The included randomised controlled trial reported a between-group mean difference of 4.6 points ( p = .027) in the VEINES-QOL score and \u22122.0 points ( p = .14) in the Villalta score, in favour of exercise therapy. The statistical significance threshold was not reached.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Data on exercise in PTS remains sparse but exercise appears to be a safe intervention. In the context of this literature, a potential future trial and outcome reporting measures are suggested.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/02683555221129738","type":"journal-article","created":{"date-parts":[[2022,9,27]],"date-time":"2022-09-27T02:07:20Z","timestamp":1664244440000},"page":"695-700","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Systematic review of exercise therapy in the management of post-thrombotic syndrome"],"prefix":"10.1177","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7703-2084","authenticated-orcid":false,"given":"Sara","family":"Jasionowska","sequence":"first","affiliation":[{"name":"Section of Vascular Surgery, Department of Surgery and Cancer, Imperial College London, London, UK"},{"name":"Imperial Vascular Unit, Imperial College Healthcare NHS Trust, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benedict R H","family":"Turner","sequence":"additional","affiliation":[{"name":"Section of Vascular Surgery, Department of Surgery and Cancer, Imperial College London, London, UK"},{"name":"Imperial Vascular Unit, Imperial College Healthcare NHS Trust, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9692-4552","authenticated-orcid":false,"given":"Matthew","family":"Machin","sequence":"additional","affiliation":[{"name":"Section of Vascular Surgery, Department of Surgery and Cancer, Imperial College London, London, UK"},{"name":"Imperial Vascular Unit, Imperial College Healthcare NHS Trust, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Onida","sequence":"additional","affiliation":[{"name":"Section of Vascular Surgery, Department of Surgery and Cancer, Imperial College London, London, UK"},{"name":"Imperial Vascular Unit, Imperial College Healthcare NHS Trust, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5913-2273","authenticated-orcid":false,"given":"Adam M","family":"Gwozdz","sequence":"additional","affiliation":[{"name":"Section of Vascular Surgery, Department of Surgery and Cancer, Imperial College London, London, UK"},{"name":"Imperial Vascular Unit, Imperial College Healthcare NHS Trust, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Shalhoub","sequence":"additional","affiliation":[{"name":"Section of Vascular Surgery, Department of Surgery and Cancer, Imperial College London, London, UK"},{"name":"Imperial Vascular Unit, Imperial College Healthcare NHS Trust, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5261-6913","authenticated-orcid":false,"given":"Alun H","family":"Davies","sequence":"additional","affiliation":[{"name":"Section of Vascular Surgery, Department of Surgery and Cancer, Imperial College London, London, UK"},{"name":"Imperial Vascular Unit, Imperial College Healthcare NHS Trust, London, 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