{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T04:09:19Z","timestamp":1790827759162,"version":"4.1.0"},"reference-count":15,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2022,12,15]],"date-time":"2022-12-15T00:00:00Z","timestamp":1671062400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Tactile Medical"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Phlebology"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Does short-term use of pneumatic compression devices (PCD) and off-the-shelf compression alleviate symptoms and improve quality of life in women with lipedema and secondary lipolymphedema?<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Prospective, randomized controlled, industry-sponsored, proof-in-principle study comparing PCD plus conservative care (PCD+CC) to CC alone (control). Adult females with bilateral lipedema and secondary lymphedema were randomized to PCD+CC or CC. Outcome measures were lower limb and truncal circumferential measurements, bioimpedance, and quality-of-life, symptom, and pain intensity questionnaires.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Both groups experienced improvements in leg circumference and bioimpedance with more improvement in the PCD+CC group than the CC group. Pain scores of the SF-36 survey and numerical rating scales were improved in the PCD+CC group. Wong\u2013Baker Faces scores showed trends toward improvement in both groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This proof-in-principle study supports conservative management with graduated compression and with or without PCD for improvement in leg circumference, bioimpedance measurements, and pain in patients with lipedema.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/02683555221145779","type":"journal-article","created":{"date-parts":[[2022,12,15]],"date-time":"2022-12-15T05:44:03Z","timestamp":1671083043000},"page":"51-61","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":31,"title":["Effect of pneumatic compression device and stocking use on symptoms and quality of life in women with lipedema: A proof-in-principle randomized trial"],"prefix":"10.1177","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4900-2800","authenticated-orcid":false,"given":"Thomas","family":"Wright","sequence":"first","affiliation":[{"name":"Laser Lipo and Vein Center, O\u2019Fallon, MO, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Crystal D.","family":"Scarfino","sequence":"additional","affiliation":[{"name":"Laser Lipo and Vein Center, O\u2019Fallon, MO, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3751-764X","authenticated-orcid":false,"given":"Ellen M.","family":"O\u2019Malley","sequence":"additional","affiliation":[{"name":"O\u2019Malley Medical Communications, LLC, Victoria, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,12,15]]},"reference":[{"key":"bibr1-02683555221145779","first-page":"443","volume-title":"Lehrbuch der Lymphologie f\u00fcr Mediziner, Masseure und Physiotherapeuten","author":"Foldi E","year":"2005"},{"key":"bibr2-02683555221145779","doi-asserted-by":"publisher","DOI":"10.1089\/lrb.2019.0011"},{"key":"bibr3-02683555221145779","doi-asserted-by":"publisher","DOI":"10.1055\/s-0039-1697904"},{"key":"bibr4-02683555221145779","doi-asserted-by":"publisher","DOI":"10.1177\/0268355519885217"},{"key":"bibr5-02683555221145779","doi-asserted-by":"publisher","DOI":"10.1002\/oby.23458"},{"key":"bibr6-02683555221145779","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2013.07.012"},{"key":"bibr7-02683555221145779","doi-asserted-by":"publisher","DOI":"10.1089\/lrb.2014.0038"},{"key":"bibr8-02683555221145779","doi-asserted-by":"publisher","DOI":"10.1016\/j.avsg.2015.07.004"},{"key":"bibr9-02683555221145779","doi-asserted-by":"publisher","DOI":"10.1089\/lrb.2020.0019"},{"issue":"4","key":"bibr10-02683555221145779","first-page":"178","volume":"44","author":"Szolnoky G","year":"2011","journal-title":"Lymphology"},{"key":"bibr11-02683555221145779","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000002019"},{"issue":"4","key":"bibr12-02683555221145779","first-page":"170","volume":"49","author":"Executive Committee","year":"2016","journal-title":"Lymphology"},{"key":"bibr13-02683555221145779","first-page":"e927804","volume":"26","author":"Zhang L","year":"2020","journal-title":"Med Sci Monit"},{"key":"bibr14-02683555221145779","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000023722"},{"key":"bibr15-02683555221145779","doi-asserted-by":"publisher","DOI":"10.1111\/pme.12528"}],"container-title":["Phlebology: The Journal of Venous Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02683555221145779","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/02683555221145779","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02683555221145779","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T17:53:21Z","timestamp":1777658001000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/02683555221145779"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,15]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,2]]}},"alternative-id":["10.1177\/02683555221145779"],"URL":"https:\/\/doi.org\/10.1177\/02683555221145779","relation":{},"ISSN":["0268-3555","1758-1125"],"issn-type":[{"value":"0268-3555","type":"print"},{"value":"1758-1125","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,15]]}}}