{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T23:59:17Z","timestamp":1789343957334,"version":"build-2803163510"},"reference-count":19,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2024,10,7]],"date-time":"2024-10-07T00:00:00Z","timestamp":1728259200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Datt Mediproducts Pvt Ltd","award":["NA"],"award-info":[{"award-number":["NA"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Phlebology"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>An open label, single-centric, post market clinical study was undertaken to evaluate the safety and efficacy of a new antimicrobial wound dressing (VELVERT) as an adjuvant therapy in the treatment of venous leg ulcer (VLU).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients with VLU of grade C-5 according to CEAP classification and above were evaluated using doppler ultra sound. The efficacy of new antimicrobial wound dressing (VELVERT) was assessed in terms of wound area reduction within a time frame of 60 days and surgeon questioners. Patients were evaluated for VELVERT safety and pain level on a scale of 0-10 Numeric Pain Chart. Presence of micro-organism load was monitored at regular time interval.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>VELVERT treatment was effective as 71.43% reduction in the ulcer area was observed. After 60 days, a total of 9 (45%) patients had complete ulcer closure. A remarkable decrease in the severity of pain was observed with 11 (55%) patients expressing no pain at the EOT. Swab test showed negative result for micro-organism growth. No serious adverse events were observed during the trial.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The data indicates that VELVERT is an effective treatment for VLUs and showed the potential in the wound care of VLUs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/02683555241288729","type":"journal-article","created":{"date-parts":[[2024,10,8]],"date-time":"2024-10-08T02:27:50Z","timestamp":1728354470000},"page":"255-265","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["An open label, single-centric, post market clinical study to evaluate the safety and efficacy of a new antimicrobial wound dressing (VELVERT) as an adjuvant therapy in the treatment of venous leg ulcer"],"prefix":"10.1177","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2918-6668","authenticated-orcid":false,"given":"Sudhir","family":"Kumar","sequence":"first","affiliation":[{"name":"Department of Plastic Surgery, MLB Medical College, Jhansi, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-6042-6950","authenticated-orcid":false,"given":"Suvash","family":"Sahu","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, MLB Medical College, Jhansi, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-8013-7866","authenticated-orcid":false,"given":"Shivam","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, MLB Medical College, Jhansi, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,10,7]]},"reference":[{"key":"e_1_3_7_2_2","doi-asserted-by":"publisher","DOI":"10.4103\/2229-5178.137819"},{"key":"e_1_3_7_3_2","volume-title":"StatPearls","author":"Robles-Tenorio A","year":"2024","unstructured":"Robles-Tenorio A, Lev-Tov H, Ocampo-Candiani J. Venous leg ulcer. In: StatPearls. Treasure Island (FL): StatPearls Publishing, 2024. Available from: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK567802\/"},{"key":"e_1_3_7_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/ddg.13242"},{"key":"e_1_3_7_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2007.08.038"},{"key":"e_1_3_7_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10354-016-0465-y"},{"key":"e_1_3_7_7_2","doi-asserted-by":"publisher","DOI":"10.12968\/jowc.2002.11.7.26414"},{"key":"e_1_3_7_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/0195-6701(91)90172-5"},{"issue":"20","key":"e_1_3_7_9_2","first-page":"S32","article-title":"Exudate, infection and patient quality of life","volume":"19","author":"Benbow M","year":"2010","unstructured":"Benbow M, Stevens J. Exudate, infection and patient quality of life. Br J Nurs 2010; 19(20): S32\u2013S36.","journal-title":"Br J Nurs"},{"key":"e_1_3_7_10_2","first-page":"CD010878","article-title":"Endovenous ablation therapy (laser or radiofrequency) or foam sclerotherapy versus conventional surgical repair for short saphenous varicose veins","volume":"11","author":"Paravastu SCV","year":"2016","unstructured":"Paravastu SCV, Horne M, Dodd PDF. Endovenous ablation therapy (laser or radiofrequency) or foam sclerotherapy versus conventional surgical repair for short saphenous varicose veins. Cochrane Database Syst Rev 2016; 11: CD010878. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc-\/articles\/PMC6464398\/","journal-title":"Cochrane Database Syst Rev"},{"issue":"6","key":"e_1_3_7_11_2","first-page":"CD012583","article-title":"Dressings and topical agents for treating venous leg ulcers","volume":"6","author":"Norman G","year":"2018","unstructured":"Norman G, Westby MJ, Rithalia AD, et al. Dressings and topical agents for treating venous leg ulcers. Cochrane Database Syst Rev 2018; 6(6): CD012583.","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_3_7_12_2","first-page":"61","article-title":"New advances in compression therapy for venous leg ulcers","volume":"23","author":"Woo KY","year":"2013","unstructured":"Woo KY, Alavi A, Evans R, et al. New advances in compression therapy for venous leg ulcers. Surg Technol Int 2013; 23: 61\u201368.","journal-title":"Surg Technol Int"},{"key":"e_1_3_7_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-475X.2007.00205.x"},{"key":"e_1_3_7_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/WON.0b013e3181aaef7f"},{"key":"e_1_3_7_15_2","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7525-5-44"},{"key":"e_1_3_7_16_2","doi-asserted-by":"publisher","unstructured":"O'Meara S Martyn-St James M. Foam dressings for venous leg ulcers. Cochrane Database of Systematic Reviews 2013 Issue 5. Art. No.: CD009907. 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