{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T22:30:20Z","timestamp":1792881020271,"version":"4.5.0"},"reference-count":32,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2025,2,14]],"date-time":"2025-02-14T00:00:00Z","timestamp":1739491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Phlebology"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To evaluate the presence of lipedema and lipedema-related factors in fibromyalgia patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The study included 100 female patients over the age of 18 who met the fibromyalgia diagnostic criteria. The patients were evaluated for the presence\/stages of lipedema. The body mass index (BMI), waist-hip ratio, waist-height ratio, and presence of hematoma tendency\/telangiectasias were recorded. Patients were asked to mark the severity of their pain (widespread\/on lipedema) on a 10\u00a0cm visual analog scale (VAS). The ACR 2016 Fibromyalgia Diagnostic Criteria, The Beck Depression Inventory (BDI), and The Revised Fibromyalgia Impact Questionnaire were applied.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Lipedema was observed in 50% of the patients (58% Stage 1 lipedema). In the lipedema group, age, duration of fibromyalgia diagnosis, hematoma tendency\/presence of telangiectasias (for all;\n                      <jats:italic>p<\/jats:italic>\n                      &lt; .001), menopausal status (\n                      <jats:italic>p<\/jats:italic>\n                      = .004), BDI score (\n                      <jats:italic>p<\/jats:italic>\n                      = .04), BMI (\n                      <jats:italic>p<\/jats:italic>\n                      = .02), history of medication for fibromyalgia (\n                      <jats:italic>p<\/jats:italic>\n                      = .01) were higher, and age at menarche (\n                      <jats:italic>p<\/jats:italic>\n                      = .01) was lower. Lipedema stage was moderately positively correlated with BMI, number of pregnancies (for both; r:0.53\n                      <jats:italic>p<\/jats:italic>\n                      &lt; .001) and waist-height ratio (r:0.43\n                      <jats:italic>p<\/jats:italic>\n                      :0.002), while VAS-lipedema pain intensity was strongly positively correlated with VAS-widespread pain intensity (r:0.62\n                      <jats:italic>p<\/jats:italic>\n                      &lt; .001), and moderately positively correlated with symptom severity score (r:0.55\n                      <jats:italic>p<\/jats:italic>\n                      &lt; .001), BMI (r:0.54\n                      <jats:italic>p<\/jats:italic>\n                      &lt; .001), and fibromyalgia severity score (r:0.51\n                      <jats:italic>p<\/jats:italic>\n                      &lt; .001). Long fibromyalgia diagnosis time (\n                      <jats:italic>p<\/jats:italic>\n                      : 0.005), and low age at menarche (\n                      <jats:italic>p<\/jats:italic>\n                      : 0.05) were significant risk factors for the presence of lipedema.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Lipedema is common in fibromyalgia patients. Long fibromyalgia diagnosis time and low age at menarche are significant risk factors for the presence of lipedema.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/02683555251321042","type":"journal-article","created":{"date-parts":[[2025,2,14]],"date-time":"2025-02-14T07:40:46Z","timestamp":1739518846000},"page":"559-569","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Lipedema awareness in fibromyalgia"],"prefix":"10.1177","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4000-6947","authenticated-orcid":false,"given":"Elzem","family":"Bolkan G\u00fcnayd\u0131n","sequence":"first","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Ufuk University, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zeliha","family":"\u00dcnl\u00fc","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Manisa Celal Bayar University, Manisa, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saime","family":"Ay","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Lokman Hekim University, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tolga O\u011fuz","family":"Karap\u0131nar","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Manisa Celal Bayar University, Manisa, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,2,14]]},"reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/dth.12805"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/ddg.13036"},{"issue":"9","key":"e_1_3_5_4_2","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1111\/ddg.15513","article-title":"S2k guideline lipedema","volume":"22","author":"Faerber G","unstructured":"Faerber G, Cornely M, Daubert C, et al. S2k guideline lipedema. JDDG J der Deutschen Dermatol Gesellschaft. 202;22(9):1303\u20131315. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/39188170\/","journal-title":"JDDG J der Deutschen Dermatol Gesellschaft"},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.12968\/jowc.2020.29.Sup11b.1"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph181910223"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mehy.2014.08.011"},{"issue":"22","key":"e_1_3_5_8_2","first-page":"396","article-title":"Lipedema-pathogenesis, diagnosis, and treatment options","volume":"117","author":"Kruppa P","year":"2020","unstructured":"Kruppa P, Georgiou I, Ghods M, et al. Lipedema-pathogenesis, diagnosis, and treatment options. Dtsch Arztebl Int [Internet] 2020; 117(22\u201323): 396\u2013403, Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/32762835\/","journal-title":"Dtsch Arztebl Int [Internet]"},{"key":"e_1_3_5_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.12949"},{"key":"e_1_3_5_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2023.05.056"},{"key":"e_1_3_5_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/GOX.0000000000001043"},{"key":"e_1_3_5_12_2","doi-asserted-by":"publisher","DOI":"10.1089\/lrb.2023.0062"},{"key":"e_1_3_5_13_2","unstructured":"Brorson H Corda D Greco F et al. Report of the diagnosis working group the international lipoedema association. 2022."},{"key":"e_1_3_5_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/dth.14364"},{"issue":"10","key":"e_1_3_5_15_2","first-page":"e48032","article-title":"Beyond the pain: a systematic narrative review of the latest advancements in fibromyalgia treatment","volume":"15","author":"Ram PR","year":"2023","unstructured":"Ram PR, Jeyaraman M, Jeyaraman N, et al. Beyond the pain: a systematic narrative review of the latest advancements in fibromyalgia treatment. 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