{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T11:30:15Z","timestamp":1789471815408,"version":"build-2803163510"},"reference-count":36,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2025,8,5]],"date-time":"2025-08-05T00:00:00Z","timestamp":1754352000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Natural Science Foundation of Shanghai Minhang District","award":["2024MHZ102"],"award-info":[{"award-number":["2024MHZ102"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Phlebology"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>This multicenter retrospective study sought to compare the efficacy and safety of endovenous laser ablation (EVLA) versus radiofrequency ablation (RFA) for treating great saphenous vein (GSV) incompetence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We performed propensity score matching (PSM) between 864 EVLA and 1009 RFA cases. Primary endpoints comprised complete venous ablation (efficacy) and incidence of deep vein thrombosis (DVT) and endovenous heat-induced thrombosis (EHIT) (safety). Secondary outcomes assessed at serial follow-ups included: Numerical Rating Scale (NRS) pain scores, cutaneous adverse events, Venous Clinical Severity Score (VCSS), and Chronic Venous Insufficiency Questionnaire (CIVIQ-20).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The propensity-matched cohort (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 855 per group) showed balanced baseline characteristics after exclusions (all\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &gt; .05). Primary efficacy analysis revealed significantly lower 24-month recurrence rates with EVLA versus RFA (5.6% vs 10.2%,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; .001). Primary safety outcomes demonstrated reduced thrombotic complications with RFA, including lower DVT incidence (0.7% vs 1.8%,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = .048) and decreased EHIT formation (Class 0: 93.9% vs 89.7%; grades 1-4: 6.1% vs 10.3%,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = .034). Secondary analysis showed RFA\u2019s advantages in pain profiles (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; .001), cutaneous complications (skin burns: 2.7% vs 4.7%,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = .029), and superior therapeutic improvement through 24 months (VCSS: 0.66 \u00b1 0.15 vs 1.66 \u00b1 0.55,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = .029; CIVIQ-20: 5.66 \u00b1 1.10 vs 10.66 \u00b1 2.69,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = .006).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>RFA demonstrates superior perioperative safety profiles, symptom relief, and quality-of-life outcomes. However, its significantly higher long-term recurrence risk compared to EVLA necessitates risk-stratified treatment algorithms.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/02683555251366380","type":"journal-article","created":{"date-parts":[[2025,8,6]],"date-time":"2025-08-06T02:28:30Z","timestamp":1754447310000},"page":"348-357","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Comparison of the safety and efficacy between endovenous laser ablation and radiofrequency ablation for great saphenous vein incompetence"],"prefix":"10.1177","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-1371-3595","authenticated-orcid":false,"given":"Xianhao","family":"Su","sequence":"first","affiliation":[{"name":"Fudan University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongjian","family":"Ding","sequence":"additional","affiliation":[{"name":"Fudan University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiyu","family":"Pan","sequence":"additional","affiliation":[{"name":"Fudan University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huaqing","family":"Li","sequence":"additional","affiliation":[{"name":"Fudan University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianing","family":"Yue","sequence":"additional","affiliation":[{"name":"Fudan University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Chen","sequence":"additional","affiliation":[{"name":"Fudan University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,8,5]]},"reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvsv.2024.101944"},{"key":"e_1_3_5_3_2","first-page":"170853812412730","article-title":"Interventions for great saphenous vein insufficiency: a systematic review and network meta-analysis","author":"Juhani AA","year":"2024","unstructured":"Juhani AA, Abdullah A, Alyaseen EM, et al. Interventions for great saphenous vein insufficiency: a systematic review and network meta-analysis. Vascular 2024; 17085381241273098.","journal-title":"Vascular"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvsv.2021.10.009"},{"issue":"8","key":"e_1_3_5_5_2","first-page":"CD005624","article-title":"Interventions for great saphenous vein incompetence","volume":"8","author":"Whing J","year":"2021","unstructured":"Whing J, Nandhra S, Nesbitt C, et al. Interventions for great saphenous vein incompetence. 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Hybrid endovenous laser ablation reduces the recurrence of varicose veins below the knee compared with radiofrequency ablation: a real-world study. 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