{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T09:17:33Z","timestamp":1778923053832,"version":"3.51.4"},"reference-count":15,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T00:00:00Z","timestamp":1756944000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Science Valley Research Institute"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Phlebology"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Sclerotherapy with polidocanol is the gold standard treatment for telangiectasias and varicose veins, but technologies such as transdermal radiofrequency are also available. Transdermal radiofrequency (V Eraser\n                      <jats:sup>\u00ae)<\/jats:sup>\n                      , a device that combines transdermal radiofrequency and sclerotherapy, was developed to treat these conditions.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was a prospective, randomized, and comparative study between transdermal radiofrequency and sclerotherapy for treating telangiectasias and reticular veins. Forty-one patients were randomized to either transdermal radiofrequency plus polidocanol sclerotherapy or polidocanol sclerotherapy alone and underwent a single treatment session. Efficacy was assessed using vessel clearance analysis in pre- and post-treatment images and the Aberdeen Varicose Vein Questionnaire.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Forty-six patients were enrolled. Both treatments significantly reduced vessel length in a single session (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; .001). Sclerotherapy showed an average reduction of 30.7%, while transdermal radiofrequency reduced it by 33%, with no statistically significant difference (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = .596). Quality of life improved, with pain reduction in 40% and 55% of patients in the right and left lower limbs, respectively (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = .030 and\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = .002).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Transdermal radiofrequency was not superior to standard of care polidocanol sclerotherapy. Both methods improved quality of life, particularly in reducing pain associated with varicose veins.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/02683555251375384","type":"journal-article","created":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T12:52:30Z","timestamp":1756990350000},"page":"410-418","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Transdermal radiofrequency (V ERASER\u00ae) plus polidocanol sclerotherapy\n                    <i>versus<\/i>\n                    polidocanol sclerotherapy alone for the treatment of reticular veins and telangiectasias. A randomized controlled trial (TYPER trial)"],"prefix":"10.1177","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-0551-1410","authenticated-orcid":false,"given":"Rebeca","family":"Higino Becker","sequence":"first","affiliation":[{"name":"Vascular Surgery Department, Faculdade de Ci\u00eancias M\u00e9dicas da Santa Casa de S\u00e3o Paulo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto Augusto","family":"Caffaro","sequence":"additional","affiliation":[{"name":"Vascular Surgery Department, Faculdade de Ci\u00eancias M\u00e9dicas da Santa Casa de S\u00e3o Paulo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-3588-3370","authenticated-orcid":false,"given":"Caroline C\u00e2ndida Carvalho","family":"de Oliveira","sequence":"additional","affiliation":[{"name":"Vascular Surgery Department, Faculdade de Ci\u00eancias M\u00e9dicas da Santa Casa de S\u00e3o 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Paulo"},{"name":"Vascular Surgery Department, Centro Universit\u00e1rio S\u00e3o Lucas Ji-Paran\u00e1"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-4379-4920","authenticated-orcid":false,"given":"Mariana Ferreira Borges Firmo","family":"Rodrigues","sequence":"additional","affiliation":[{"name":"Vascular Surgery Department, Faculdade de Ci\u00eancias M\u00e9dicas da Santa Casa de S\u00e3o Paulo"},{"name":"Vascular Surgery Department, Universidade do Rio Grande \u2013 FURG, Rio Grande"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-0520-0503","authenticated-orcid":false,"given":"Viviane Santana","family":"da Silva","sequence":"additional","affiliation":[{"name":"Clinical Trials Department, Science Valley Research Institute"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6972-5830","authenticated-orcid":false,"given":"Camilla 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Cryo-laser and cryo-sclerotherapy guided by augmented reality for telangiectasias, feeder, and small varicose vein treatment \u2013 the CLaCS technique white paper report. 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