{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T03:38:52Z","timestamp":1793417932880,"version":"4.5.0"},"reference-count":14,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2026,1,4]],"date-time":"2026-01-04T00:00:00Z","timestamp":1767484800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Phlebology"],"published-print":{"date-parts":[[2026,9]]},"abstract":"\n Background<\/jats:title>\n Mechanochemical endovenous ablation (MOCA) is an established non-thermal technique for treating varicose veins of the great and small saphenous veins, GSV and SSV, with diameters under 12\u00a0mm. However, its safety and efficacy in treating anterior saphenous vein (ASV) incompetence remain unclear. This study evaluated the feasibility, safety, and effectiveness of MOCA for ASV reflux.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n In this prospective single-centre registry, 30 patients with symptomatic ASV incompetence underwent MOCA using the ClariVein\u00ae system. Anatomical success, clinical improvement (VCSS), pain scores, return to normal activities, and complications were assessed at 30-days and 12-months follow-up. Procedural duration and duplex ultrasound results were also recorded.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n Technical success was achieved in 93.3% (28\/30) of patients. Median procedure time was 9.0\u00a0min (IQR 7.0\u201311.5). Median peri-procedural and postoperative pain scores were 3.0 and 1.0, respectively, and most patients resumed normal activities within 1\u00a0day. At 30 days, anatomical success was 96.3%, and median VCSS improved from 5.0 to 3.0. At 12 months, duplex ultrasound was available in 25 patients, with evaluable data in 23. Complete occlusion was observed in 82.6%, partial in 4.3%, and no occlusion in 13.0%. Minor complications occurred in 25.0%, and one deep vein thrombosis was recorded. At 1\u00a0year, the mean AVVQ score improved by 6.7 points, and RAND-36 scores showed favourable outcomes in pain (81), mental health (85), and general health (64).<\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n MOCA with the ClariVein\u00ae system appears safe, effective, and well-tolerated for ASV incompetence. Larger studies with longer follow-up are warranted.<\/jats:p>\n <\/jats:sec>","DOI":"10.1177\/02683555251413984","type":"journal-article","created":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T06:22:49Z","timestamp":1767594169000},"page":"669-674","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Treatment of anterior saphenous vein incompetence with mechanochemical endovenous ablation"],"prefix":"10.1177","volume":"41","author":[{"given":"Marianne E.","family":"Witte","sequence":"first","affiliation":[{"name":"Nij Smellinghe Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7641-1322","authenticated-orcid":false,"given":"Suzanne","family":"Holewijn","sequence":"additional","affiliation":[{"name":"Rijnstate Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel M. P. J.","family":"Reijnen","sequence":"additional","affiliation":[{"name":"Rijnstate Hospital"},{"name":"University of Twente"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5011-4124","authenticated-orcid":false,"given":"Clark J.","family":"Zeebregts","sequence":"additional","affiliation":[{"name":"University of Groningen"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,1,4]]},"reference":[{"key":"e_1_3_6_2_2","first-page":"219","article-title":"Mechanochemical endovenous occlusion of varicose veins using the ClariVein\u00ae device","volume":"26","author":"Witte ME","year":"2015","unstructured":"Witte ME, Reijnen MMPJ, de Vries JP, et al. Mechanochemical endovenous occlusion of varicose veins using the ClariVein\u00ae device. Surg Technol Int 2015; 26: 219\u2013225.","journal-title":"Surg Technol Int"},{"key":"e_1_3_6_3_2","doi-asserted-by":"publisher","DOI":"10.1177\/0268355517702068"},{"key":"e_1_3_6_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvsv.2018.12.014"},{"key":"e_1_3_6_5_2","doi-asserted-by":"publisher","DOI":"10.1177\/0268355519861464"},{"key":"e_1_3_6_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0741-5214(97)70084-3"},{"key":"e_1_3_6_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2021.12.024"},{"key":"e_1_3_6_8_2","first-page":"66","article-title":"What a phlebologist should know about the anterior accessory saphenous vein?","volume":"26","author":"De Maeseneer M","year":"2019","unstructured":"De Maeseneer M. What a phlebologist should know about the anterior accessory saphenous vein? Phlebolymphology 2019; 26: 66\u201371.","journal-title":"Phlebolymphology"},{"key":"e_1_3_6_9_2","volume-title":"Introduction to the RUC: the AMA\/Specialty Society RVS Update Committee","author":"American Medical Association","year":"2023","unstructured":"American Medical Association. Introduction to the RUC: the AMA\/Specialty Society RVS Update Committee. : American Medical Association, 2023."},{"key":"e_1_3_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvsv.2024.101967"},{"key":"e_1_3_6_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2008.11.035"},{"key":"e_1_3_6_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvsv.2021.08.010"},{"key":"e_1_3_6_13_2","first-page":"36","article-title":"Endovenous thermal ablation of the anterior accessory great saphenous vein","author":"Laredo J","year":"2010","unstructured":"Laredo J, Lee BB, Neville RF. Endovenous thermal ablation of the anterior accessory great saphenous vein. Endovasc Today 2010: 36\u201339.","journal-title":"Endovasc Today"},{"key":"e_1_3_6_14_2","first-page":"1117","article-title":"A single-center experience of anterior accessory great saphenous vein treatment using endothermal ablation","volume":"10","author":"Chahine E","year":"2022","unstructured":"Chahine E, Zang J, Siracuse JJ, et al. A single-center experience of anterior accessory great saphenous vein treatment using endothermal ablation. J Vasc Surg Venous Lymphat Disord 2022; 10: 1117\u20131122.","journal-title":"J Vasc Surg Venous Lymphat Disord"},{"key":"e_1_3_6_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2025.04.038"}],"container-title":["Phlebology: The Journal of Venous Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02683555251413984","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/02683555251413984","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02683555251413984","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T23:21:18Z","timestamp":1787095278000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/02683555251413984"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,4]]},"references-count":14,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1177\/02683555251413984"],"URL":"https:\/\/doi.org\/10.1177\/02683555251413984","relation":{},"ISSN":["0268-3555","1758-1125"],"issn-type":[{"value":"0268-3555","type":"print"},{"value":"1758-1125","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,4]]}}}