{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T09:10:05Z","timestamp":1789809005428,"version":"4.0.1"},"reference-count":21,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T00:00:00Z","timestamp":1789516800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Phlebology"],"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Chronic venous insufficiency (CVI) and varicose veins have been associated with restless legs syndrome (RLS), impaired sleep quality, and reduced quality of life. This study aimed to evaluate the effects of endovenous radiofrequency ablation (RFA) on RLS severity, daytime sleepiness, and sleep quality in patients with symptomatic venous insufficiency.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methodology<\/jats:title>\n                    <jats:p>This pre\u2013post intervention study included 160 consecutive patients with venous insufficiency who underwent endovenous RFA between January 2022 and January 2023. Restless legs syndrome severity, daytime sleepiness, and sleep quality were assessed before and within 3\u00a0months after surgery using the Restless Legs Syndrome Rating Scale (RLSS), Epworth Sleepiness Scale (ESS), and Pittsburgh Sleep Quality Index (PSQI), respectively. Changes in clinical scores following treatment were analyzed using appropriate statistical methods.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The mean age of the participants was 48.7 \u00b1 10.6\u00a0years, and 68.1% were female. Following RFA, RLSS scores decreased significantly from a median of 21 to 7 (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; 0.001), indicating a marked reduction in RLS severity. Sleep quality also improved significantly, with PSQI scores decreasing from a median of 6 to 4 (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; 0.001). The proportion of patients with poor sleep quality declined from 68.8% to 41.9% (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; 0.001). Although ESS scores decreased significantly (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u00a0&lt; 0.001), the prevalence of excessive daytime sleepiness did not change significantly after treatment (7.5% vs. 5.6%,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.317).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Endovenous radiofrequency ablation was associated with significant improvements in restless legs syndrome symptoms and sleep quality in patients with chronic venous insufficiency. These findings suggest that treatment of venous insufficiency may contribute to better sleep-related outcomes and should be considered in patients presenting with both venous symptoms and sleep disturbances.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/02683555261490768","type":"journal-article","created":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T23:12:41Z","timestamp":1789600361000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of endovenous radiofrequency ablation on restless legs syndrome severity and sleep quality in patients with chronic venous insufficiency"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2110-9967","authenticated-orcid":false,"given":"Zeynep Vildan","family":"Okudan Atay","sequence":"first","affiliation":[{"name":"Bak\u0131rk\u00f6y Dr. Sadi Konuk Training and Research Hospital"},{"name":"Forensic Medicine \u0130nstitution"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u0130brahim","family":"Ac\u0131r","sequence":"additional","affiliation":[{"name":"Oxford University Hospitals Trust"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0011-190X","authenticated-orcid":false,"given":"Mehmet","family":"Atay","sequence":"additional","affiliation":[{"name":"Bah\u00e7elievler Public Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vildan","family":"Yayla","sequence":"additional","affiliation":[{"name":"Bak\u0131rk\u00f6y Dr. Sadi Konuk Training and Research Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,9,16]]},"reference":[{"key":"e_1_3_7_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2021.12.024"},{"key":"e_1_3_7_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1389-9457(03)00010-8"},{"key":"e_1_3_7_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/jsr.13632"},{"key":"e_1_3_7_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/22.7.961"},{"issue":"4","key":"e_1_3_7_6_2","first-page":"380","article-title":"Sleep medicine: restless legs syndrome","volume":"115","author":"Bollu PC","year":"2018","unstructured":"Bollu PC, Yelam A, Thakkar MM. Sleep medicine: restless legs syndrome. Mo Med 2018; 115(4): 380\u2013387.","journal-title":"Mo Med"},{"key":"e_1_3_7_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2017.08.033"},{"key":"e_1_3_7_8_2","doi-asserted-by":"publisher","DOI":"10.1177\/026835550201700106"},{"issue":"3","key":"e_1_3_7_9_2","first-page":"258","article-title":"Chronic venous disease: health status of a population and care impact on this health status through quality-of-life questionnaires","volume":"24","author":"Guex JJ","year":"2005","unstructured":"Guex JJ, Myon E, Didier L, et al. Chronic venous disease: health status of a population and care impact on this health status through quality-of-life questionnaires. Int Angiol 2005; 24(3): 258\u2013264.","journal-title":"Int Angiol"},{"key":"e_1_3_7_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvir.2022.12.019"},{"key":"e_1_3_7_11_2","doi-asserted-by":"publisher","DOI":"10.1177\/0268355513483280"},{"key":"e_1_3_7_12_2","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/32.5.589"},{"key":"e_1_3_7_13_2","doi-asserted-by":"publisher","DOI":"10.1212\/CON.0000000000000488"},{"key":"e_1_3_7_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11325-022-02676-1"},{"issue":"4","key":"e_1_3_7_15_2","first-page":"e4368","article-title":"Treatment of leg veins for restless leg syndrome: a retrospective review","volume":"11","author":"Sundaresan S","year":"2019","unstructured":"Sundaresan S, Migden MR, Silapunt S. Treatment of leg veins for restless leg syndrome: a retrospective review. Cureus 2019; 11(4): e4368. https:\/\/doi.org\/10.7759\/cureus.4368","journal-title":"Cureus"},{"key":"e_1_3_7_16_2","doi-asserted-by":"publisher","DOI":"10.1258\/026835507781477145"},{"key":"e_1_3_7_17_2","first-page":"933","article-title":"Sleep quality, obstructive sleep apnea syndrome, and symptoms in patients with varicose veins: the effect of regular compression stocking use","volume":"32","author":"At\u0131k D","year":"2016","unstructured":"At\u0131k D, Erdo\u011fan Z, Karatepe H, et al. Sleep quality, obstructive sleep apnea syndrome, and symptoms in patients with varicose veins: the effect of regular compression stocking use. Acta Med Mediterr 2016; 32: 933\u2013940.","journal-title":"Acta Med Mediterr"},{"key":"e_1_3_7_18_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40119-021-00213-x"},{"key":"e_1_3_7_19_2","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/14.6.540"},{"key":"e_1_3_7_20_2","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/15.4.376"},{"key":"e_1_3_7_21_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.23397"},{"key":"e_1_3_7_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2014.05.009"}],"container-title":["Phlebology: The Journal of Venous Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02683555261490768","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/02683555261490768","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02683555261490768","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T08:20:18Z","timestamp":1789806018000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/02683555261490768"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,16]]},"references-count":21,"alternative-id":["10.1177\/02683555261490768"],"URL":"https:\/\/doi.org\/10.1177\/02683555261490768","relation":{},"ISSN":["0268-3555","1758-1125"],"issn-type":[{"value":"0268-3555","type":"print"},{"value":"1758-1125","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,16]]},"article-number":"02683555261490768"}}