{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T11:48:35Z","timestamp":1768564115036,"version":"3.49.0"},"reference-count":26,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2008,5,1]],"date-time":"2008-05-01T00:00:00Z","timestamp":1209600000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Rehabil"],"published-print":{"date-parts":[[2008,5]]},"abstract":"<jats:p> Objective: To evaluate the effect of whole body vibration on the mobility of long-term immobilized children and adolescents with a severe form of osteogenesis imperfecta. Osteogenesis imperfecta is a hereditary primary bone disorder with a prevalence from 1 in 10000 to 1 in 20000 births. Most of these children are suffering from long-term immobilization after recurrent fractures. Due to the immobilization they are affected by loss of muscle (sarcopenia) and secondary loss of bone mass. <\/jats:p><jats:p> Subjects: Whole body vibration was applied to eight children and adolescents (osteogenesis imperfecta type 3, N=5; osteogenesis imperfecta type 4, N=3) over a period of six months. <\/jats:p><jats:p> Interventions and results: Whole body vibration was applied by a vibrating platform (Galileo Systems) constructed on a tilting-table. Success of treatment was assessed by measuring alterations of the tilting-angle and evaluating the mobility (Brief Assessment of Motor Function). All individuals were characterized by improved muscle force documented by an increased tilting-angle (median = 35 degrees) or by an increase in ground reaction force (median at start=30.0 [N\/kg] (14.48\u2014134.21); median after six months = 146.0 [N\/kg] (42.46\u2014245.25). <\/jats:p><jats:p> Conclusions: Whole body vibration may be a promising approach to improve mobility in children and adolescents severely affected with osteogenesis imperfecta. <\/jats:p>","DOI":"10.1177\/0269215507080763","type":"journal-article","created":{"date-parts":[[2008,4,25]],"date-time":"2008-04-25T14:20:28Z","timestamp":1209133228000},"page":"387-394","source":"Crossref","is-referenced-by-count":46,"title":["Results of a prospective pilot trial on mobility after whole body vibration in children and adolescents with osteogenesis imperfecta"],"prefix":"10.1177","volume":"22","author":[{"given":"Oliver","family":"Semler","sequence":"first","affiliation":[{"name":"Children's Hospital, University of Cologne, Cologne, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oliver","family":"Fricke","sequence":"additional","affiliation":[{"name":"Children's Hospital, University of Cologne, Cologne, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katharina","family":"Vezyroglou","sequence":"additional","affiliation":[{"name":"Children's Hospital, University of Cologne, Cologne, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christina","family":"Stark","sequence":"additional","affiliation":[{"name":"Children's Hospital, University of Cologne, Cologne, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angelika","family":"Stabrey","sequence":"additional","affiliation":[{"name":"Children's Hospital, University of Cologne, Cologne, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eckhard","family":"Schoenau","sequence":"additional","affiliation":[{"name":"Children's Hospital, 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