{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:05:55Z","timestamp":1787018755092,"version":"build-2736575974"},"reference-count":34,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2017,9,12]],"date-time":"2017-09-12T00:00:00Z","timestamp":1505174400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Rehabil"],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To examine the impact of perceived limitations, stigma and sense of coherence on quality of life in multiple sclerosis patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>Cross-sectional survey.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting:<\/jats:title>\n                    <jats:p>Department of Neurology, University Medical Center Groningen, the Netherlands.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Subjects:<\/jats:title>\n                    <jats:p>Multiple sclerosis patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main measures:<\/jats:title>\n                    <jats:p>World Health Organization Quality of Life \u2013 abbreviated version, Stigma Scale for Chronic Illness, Sense of Coherence Scale, background and disease-related questions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>In total, 185 patients (61% response rate) participated in the study with moderate to severe limitations. Stigma was highly prevalent but low in severity. Patients with a higher sense of coherence experienced a lower level of limitations ( B = \u22120.063, P &lt; 0.01) and less stigma (enacted stigma B = \u22120.030, P &lt; 0.01; self-stigma B = \u22120.037, P &lt; 0.01). Patients with a higher level of limitations experienced more stigma (enacted stigma B = 0.044, P &lt; 0.05; self-stigma B = 0.063, P &lt; 0.01). Patients with a higher sense of coherence experienced better quality of life (physical health B = 0.059, P &lt; 0.01; psychological health B = 0.062, P &lt; 0.01; social relationships B = 0.052, P &lt; 0.01; environmental aspects B = 0.030, P &lt; 0.01). Patients with a higher level of limitations experienced poorer quality of life (physical health B = \u22120.364, P &lt; 0.01; psychological health B = \u22120.089, P &lt; 0.05) and patients with more stigma also experienced poorer quality of life (self-stigma: physical health B = \u22120.073, P &lt; 0.01; psychological health B = \u22120.089, P &lt; 0.01; social relationships B = \u22120.124, P &lt; 0.01; environmental aspects B = \u22120.052, P &lt; 0.01, and enacted stigma: physical health B = \u22120.085, P &lt; 0.10).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Patients with less perceived limitations and stigma and a higher level of sense of coherence experienced better quality of life. Patients with a higher sense of coherence experienced a lower level of limitations and less stigma.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0269215517730670","type":"journal-article","created":{"date-parts":[[2017,9,12]],"date-time":"2017-09-12T07:57:51Z","timestamp":1505203071000},"page":"536-545","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":46,"title":["The impact of self-perceived limitations, stigma and sense of coherence on quality of life in multiple sclerosis patients: results of a cross-sectional study"],"prefix":"10.1177","volume":"32","author":[{"given":"Feddrik","family":"Broersma","sequence":"first","affiliation":[{"name":"Department of Health Sciences, Community and Occupational Medicine, University Medical Center Groningen (UMCG), University of Groningen, Groningen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barth","family":"Oeseburg","sequence":"additional","affiliation":[{"name":"Wenckebach Institute, University Medical Center Groningen (UMCG), University of Groningen, Groningen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacob","family":"Dijkstra","sequence":"additional","affiliation":[{"name":"Department of Sociology, Faculty of Behavioural and Social Sciences, University of Groningen, Groningen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klaske","family":"Wynia","sequence":"additional","affiliation":[{"name":"Department of Health Sciences, Community and Occupational Medicine, University Medical Center Groningen (UMCG), University of Groningen, Groningen, The Netherlands"},{"name":"Department of Neurology, University Medical Center Groningen (UMCG), University of Groningen, Groningen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2017,9,12]]},"reference":[{"key":"bibr1-0269215517730670","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)61620-7"},{"key":"bibr2-0269215517730670","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-9566.2009.01161.x"},{"key":"bibr3-0269215517730670","doi-asserted-by":"publisher","DOI":"10.1080\/095401200750003798"},{"key":"bibr4-0269215517730670","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ps.52.12.1615"},{"key":"bibr5-0269215517730670","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.2008.01241.x"},{"key":"bibr6-0269215517730670","doi-asserted-by":"publisher","DOI":"10.1080\/1354850021000015203"},{"key":"bibr7-0269215517730670","doi-asserted-by":"publisher","DOI":"10.1177\/0269215513487234"},{"key":"bibr8-0269215517730670","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1080\/19401183.1986.12461516","volume":"126","author":"Antonovsky H","year":"1986","journal-title":"J Soc Psychol"},{"key":"bibr9-0269215517730670","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v21.i21.6713"},{"key":"bibr10-0269215517730670","doi-asserted-by":"publisher","DOI":"10.1186\/s12883-014-0193-0"},{"key":"bibr11-0269215517730670","doi-asserted-by":"publisher","DOI":"10.1136\/jech.2005.041616"},{"key":"bibr12-0269215517730670","doi-asserted-by":"publisher","DOI":"10.1037\/0278-6133.18.4.383"},{"key":"bibr13-0269215517730670","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2006.090654"},{"key":"bibr14-0269215517730670","doi-asserted-by":"publisher","DOI":"10.1177\/0269215517695374"},{"key":"bibr15-0269215517730670","volume-title":"The Multiple Sclerosis Impact Profile (MSIP), an ICF-based outcome measure for disability and disability perception in MS: development and psychometric testing","author":"Wynia K","year":"2008"},{"key":"bibr16-0269215517730670","doi-asserted-by":"publisher","DOI":"10.1177\/1352458511423935"},{"key":"bibr17-0269215517730670","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000000560"},{"key":"bibr18-0269215517730670","doi-asserted-by":"publisher","DOI":"10.1177\/135245850100700311"},{"key":"bibr19-0269215517730670","doi-asserted-by":"publisher","DOI":"10.1080\/09638280701476193"},{"key":"bibr20-0269215517730670","doi-asserted-by":"publisher","DOI":"10.1080\/09638280701256868"},{"key":"bibr21-0269215517730670","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291798006667"},{"key":"bibr22-0269215517730670","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-009-9475-1"},{"key":"bibr23-0269215517730670","doi-asserted-by":"publisher","DOI":"10.1016\/0277-9536(93)90033-Z"},{"key":"bibr24-0269215517730670","unstructured":"Pottie CMH. Antonovsky\u2019s sense of coherence en zijn operationalisatie van dit concept in een voor vlaanderen aangepaste vragenlijst. Unpublished Master\u2019s Thesis, KU Leuven, Leuven, 1990 (in Dutch)."},{"key":"bibr25-0269215517730670","doi-asserted-by":"publisher","DOI":"10.5334\/pb-52-4-368"},{"key":"bibr26-0269215517730670","volume-title":"Multiple regression: testing and interpreting interactions","author":"Aiken LS","year":"1991"},{"key":"bibr27-0269215517730670","doi-asserted-by":"publisher","DOI":"10.1002\/9780470515075"},{"key":"bibr28-0269215517730670","doi-asserted-by":"publisher","DOI":"10.1186\/s12883-016-0621-4"},{"key":"bibr29-0269215517730670","volume-title":"Multiple sclerose: epidemiologie en kwaliteit van leven","author":"Zwanikken CP.","year":"1997"},{"key":"bibr30-0269215517730670","doi-asserted-by":"publisher","DOI":"10.2147\/PPA.S109520"},{"key":"bibr31-0269215517730670","unstructured":"Hoeymans N, Melse JM, Schoemaker CG. Gezondheid en determinanten. Deelrapport van de VTV 2010 Van gezond naar beter (in Dutch). Available at: http:\/\/www.vtv2010.nl\/object_binary\/o9228_rivm02-gezondheid-en-determanten-vtv-2010.pdf (accessed 14 November 2016)."},{"key":"bibr32-0269215517730670","doi-asserted-by":"publisher","DOI":"10.1080\/09638288.2016.1198430"},{"key":"bibr33-0269215517730670","doi-asserted-by":"publisher","DOI":"10.1177\/0269215513501525"},{"key":"bibr34-0269215517730670","doi-asserted-by":"publisher","DOI":"10.1186\/1752-4458-2-3"}],"container-title":["Clinical Rehabilitation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0269215517730670","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0269215517730670","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0269215517730670","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T16:53:43Z","timestamp":1777395223000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0269215517730670"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9,12]]},"references-count":34,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,4]]}},"alternative-id":["10.1177\/0269215517730670"],"URL":"https:\/\/doi.org\/10.1177\/0269215517730670","relation":{},"ISSN":["0269-2155","1477-0873"],"issn-type":[{"value":"0269-2155","type":"print"},{"value":"1477-0873","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,9,12]]}}}