{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T16:41:08Z","timestamp":1790786468602,"version":"4.1.0"},"reference-count":23,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2017,10,5]],"date-time":"2017-10-05T00:00:00Z","timestamp":1507161600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Rehabil"],"published-print":{"date-parts":[[2018,5]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>The technique called Lee Silverman Voice Treatment (LSVT)-LOUD has previously been used to improve voice quality in people with Parkinson\u2019s disease. The objective of this study was to assess the effectiveness of an alternate intervention, LSVT-BIG (signifying big movements), to improve functional mobility.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>Systematic review with meta-analysis of randomized trials.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Data sources:<\/jats:title>\n                    <jats:p>Medline, Embase, CINAHL, AgeLine, Scopus and Cochrane Library were searched from inception to September 2017 using multiple search terms related to Parkinson\u2019s disease and LSVT-BIG.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Review method:<\/jats:title>\n                    <jats:p>Two researchers searched the literature for studies of the LSVT-BIG intervention of 16 sessions, delivered by a certified instructor over four weeks, to any other intervention. Outcomes related to functional ability were included. Study quality was appraised using the Cochrane Risk of Bias tool.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Four studies were included, reporting on three randomized trials of 84 participants with mild Parkinson\u2019s disease. Compared to physiotherapy exercises, or a shorter training protocol, there was a significant improvement in motor function assessed with the Unified Parkinson\u2019s Disease Rating Scale part III (mean difference = \u22123.20, 95% confidence interval = \u22125.18 to \u22121.23) and a trend towards faster Timed Up and Go performance (mean difference = \u22120.47, 95% confidence interval = \u22120.99 to 0.06) and 10-metre walk test (mean difference = \u22120.53, 95% confidence interval = \u22121.07 to 0.01).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Compared to shorter format LSVT-BIG or general exercise, LSVT-BIG was more effective at improving motor function. This provides preliminary, moderate quality evidence that amplitude-oriented training is effective in reducing motor impairments for people with mild Parkinson\u2019s disease.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0269215517734385","type":"journal-article","created":{"date-parts":[[2017,10,5]],"date-time":"2017-10-05T05:14:39Z","timestamp":1507180479000},"page":"607-618","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":71,"title":["Lee Silverman Voice Treatment (LSVT)-BIG to improve motor function in people with Parkinson\u2019s disease: a systematic review and meta-analysis"],"prefix":"10.1177","volume":"32","author":[{"given":"Michelle N","family":"McDonnell","sequence":"first","affiliation":[{"name":"School of Health Sciences, University of South Australia, Adelaide, SA, Australia"},{"name":"Stroke and Rehabilitation Research Group, Sansom Institute for Health Research, University of South Australia, Adelaide, SA, Australia"},{"name":"Alliance for Research in Exercise, Nutrition and Activity, University of South Australia, Adelaide, SA, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Briony","family":"Rischbieth","sequence":"additional","affiliation":[{"name":"School of Health Sciences, University of South Australia, Adelaide, SA, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tenille T","family":"Schammer","sequence":"additional","affiliation":[{"name":"School of Health Sciences, University of South Australia, Adelaide, SA, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chantel","family":"Seaforth","sequence":"additional","affiliation":[{"name":"School of Health Sciences, University of South Australia, Adelaide, SA, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex J","family":"Shaw","sequence":"additional","affiliation":[{"name":"School of Health Sciences, University of South Australia, Adelaide, SA, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna C","family":"Phillips","sequence":"additional","affiliation":[{"name":"School of Health Sciences, University of South Australia, Adelaide, SA, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2017,10,5]]},"reference":[{"key":"bibr1-0269215517734385","volume-title":"Lee Silverman Voice Treatment: a practical guide to treating the voice and speech disorders in Parkinson disease","author":"Ramig L","year":"1995"},{"key":"bibr2-0269215517734385","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.71.4.493"},{"key":"bibr3-0269215517734385","doi-asserted-by":"publisher","DOI":"10.1002\/1531-8257(200101)16:1<79::AID-MDS1013>3.0.CO;2-H"},{"key":"bibr4-0269215517734385","first-page":"391946","volume":"2012","author":"Fox C","year":"2012","journal-title":"Parkinsons Dis"},{"key":"bibr5-0269215517734385","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2007.131045"},{"key":"bibr6-0269215517734385","doi-asserted-by":"publisher","DOI":"10.1007\/s00221-005-0179-7"},{"key":"bibr7-0269215517734385","doi-asserted-by":"publisher","DOI":"10.2522\/ptj.20130232"},{"key":"bibr8-0269215517734385","doi-asserted-by":"publisher","DOI":"10.1186\/2046-4053-4-1"},{"key":"bibr9-0269215517734385","doi-asserted-by":"publisher","DOI":"10.1017\/S1355617714000046"},{"key":"bibr10-0269215517734385","unstructured":"Higgins JPT, Green S. 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