{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T13:23:00Z","timestamp":1793193780673,"version":"4.5.0"},"reference-count":31,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2018,12,12]],"date-time":"2018-12-12T00:00:00Z","timestamp":1544572800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Rehabil"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>(1) To compare level of function, activity, health-related quality of life (HRQoL) and satisfaction in persons with a lower extremity amputation before surgery and 6- and 12-months after implantation of an osseointegration implant and (2) to report adverse events.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>Prospective cohort study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting:<\/jats:title>\n                    <jats:p>University medical centre.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Subjects:<\/jats:title>\n                    <jats:p>A total of 40 consecutive persons (median age: 56\u2009years) who received a transfemoral (31) or transtibial (9) osseointegration implant, between April 2014 and March 2016.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Intervention:<\/jats:title>\n                    <jats:p>Osseointegration implant surgery followed by a predefined rehabilitation programme.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main measures:<\/jats:title>\n                    <jats:p>Hip abductor strength, prosthetic use, back pain frequency, postoperative pain, mobility level (Timed-Up and Go (TUG) and wheelchair-boundedness), walking ability (6\u2009minute walking test (6MWT) and walking distance in daily life), HRQoL, satisfaction regarding the prosthesis, and adverse events.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Strength, prosthetic use, walking distance, HRQoL, and satisfaction level increased significantly at 6- and 12-month follow-up compared to baseline ( P \u2a7d 0.002). The TUG showed no change at 6-month follow-up ( P = 0.420) but improved significantly at 12-month follow-up compared to baseline ( P = 0.005). Wheelchair-boundedness decreased from 12\/40 participants at baseline to 0 at follow-ups. The 6MWT ( P \u2a7e 0.038) and back pain ( P \u2a7e 0.437) did not change over time. Stump pain was present in 28\/39 and 22\/40 of the participants at 6-and 12-month follow-up, respectively. The major adverse events were managed successfully and included three dual-cone breakages and four bone fractures. An uneventful course was completed by 19\/31 transfemoral and 4\/9 transtibial bone-anchored prostheses users.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Bone-anchored prostheses lead to improved performance and appear to be safe, so they might be considered for persons with socket-related problems.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0269215518815215","type":"journal-article","created":{"date-parts":[[2018,12,12]],"date-time":"2018-12-12T04:46:16Z","timestamp":1544589976000},"page":"450-464","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":68,"title":["Functional performance and safety of bone-anchored prostheses in persons with a transfemoral or transtibial amputation: a prospective one-year follow-up cohort study"],"prefix":"10.1177","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6158-6901","authenticated-orcid":false,"given":"Ruud A","family":"Leijendekkers","sequence":"first","affiliation":[{"name":"Department of Orthopaedics, Physical Therapy, Radboud University Medical Center, Nijmegen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerben","family":"van Hinte","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Physical Therapy, Radboud University Medical Center, Nijmegen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan Paul","family":"Fr\u00f6lke","sequence":"additional","affiliation":[{"name":"Department of Surgery, Radboud University Medical Center, Nijmegen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hendrik","family":"van de Meent","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation, Radboud University Medical Center, Nijmegen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Femke","family":"Atsma","sequence":"additional","affiliation":[{"name":"Department of IQ Healthcare, Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria WG","family":"Nijhuis-van der Sanden","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Physical Therapy, Radboud University Medical Center, Nijmegen, The Netherlands"},{"name":"Department of Rehabilitation, Radboud University Medical Center, Nijmegen, The Netherlands"},{"name":"Department of IQ Healthcare, Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas J","family":"Hoogeboom","sequence":"additional","affiliation":[{"name":"Department of IQ Healthcare, Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2018,12,12]]},"reference":[{"key":"bibr1-0269215518815215","doi-asserted-by":"publisher","DOI":"10.1080\/09638288.2016.1186752"},{"key":"bibr2-0269215518815215","doi-asserted-by":"publisher","DOI":"10.1007\/s00113-016-0302-1"},{"key":"bibr3-0269215518815215","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.16.01295"},{"key":"bibr4-0269215518815215","doi-asserted-by":"publisher","DOI":"10.1186\/s12891-016-1341-z"},{"key":"bibr5-0269215518815215","doi-asserted-by":"publisher","DOI":"10.1080\/09593985.2016.1265620"},{"key":"bibr6-0269215518815215","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2013.05.020"},{"key":"bibr7-0269215518815215","unstructured":"Leijendekkers RA, Hoogeboom TJ, van Hinte G, et al. 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