{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T07:31:04Z","timestamp":1777534264383,"version":"3.51.4"},"reference-count":29,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2020,10,23]],"date-time":"2020-10-23T00:00:00Z","timestamp":1603411200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100016274","name":"omron healthcare","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100016274","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Rehabil"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>We would like to determine whether electrotherapy, specifically microcurrent therapy, increases function and decreases pain in people who have acute knee pain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>Randomized, double-blinded, placebo-controlled clinical trial.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting:<\/jats:title>\n                    <jats:p>University laboratory and patient home.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Subjects:<\/jats:title>\n                    <jats:p>A total of 52 subjects (35 females and 17 males) with acute knee pain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Intervention:<\/jats:title>\n                    <jats:p>Treatment group ( n\u2009=\u200926) wore the active microcurrent therapy device at home for 3\u2009hours per day for 4\u2009weeks and the control group ( n\u2009=\u200926) wore the placebo for 3\u2009hours per day for 4\u2009weeks.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Measures:<\/jats:title>\n                    <jats:p>Numeric Pain Rating Scale (NPRS) and Short Form 12 (SF-12) health scale were used to measure the pain level and the functionality of the participants. Secondary assessments included musculoskeletal ultrasound imaging (MSK US) and Lower Extremity Functional Scale (LEFS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>A total of 52 subjects completed the study; 26 in the treatment group and 26 in the control group. Microcurrent therapy significantly reduced pain over 4\u2009weeks. Especially week three was significant ( P\u2009&lt;\u20090.01) after adjusting for the family-wise error rate. The analysis on SF-12 revealed those with microcurrent therapy showed an increasing trend in the improvement of physical function score until week three.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>An active microcurrent therapy device decreased knee pain and increased function. Microcurrent therapy may be an alternative or used with a pharmacological approach for people with acute knee pain.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0269215520965320","type":"journal-article","created":{"date-parts":[[2020,10,23]],"date-time":"2020-10-23T13:41:38Z","timestamp":1603460498000},"page":"390-398","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Efficacy of microcurrent therapy for treatment of acute knee pain: A randomized double-blinded controlled clinical trial"],"prefix":"10.1177","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6270-0446","authenticated-orcid":false,"given":"Daryl","family":"Lawson","sequence":"first","affiliation":[{"name":"Department of Physical Therapy, Western Michigan University, Kalamazoo, MI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin H","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Statistics, Western Michigan University, Kalamazoo, MI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyun Bin","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Statistics, Western Michigan University, Kalamazoo, MI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nan","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy, Elon University, Elon, NC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tracy","family":"Llewellyn","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy, Elon University, Elon, NC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shozo","family":"Takamatsu","sequence":"additional","affiliation":[{"name":"OMRON Healthcare, Inc., Muko City, Kyoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,10,23]]},"reference":[{"key":"bibr1-0269215520965320","unstructured":"Centers for Disease Control and Prevention. 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