{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T03:17:55Z","timestamp":1792034275082,"version":"4.4.0"},"reference-count":25,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2020,11,23]],"date-time":"2020-11-23T00:00:00Z","timestamp":1606089600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"The science and technology planning project of Suzhou","award":["SYS2019102"],"award-info":[{"award-number":["SYS2019102"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Rehabil"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To explore effects of repetitive transcranial magnetic stimulation (rTMS) combined with transcranial direct current stimulation (tDCS) on motor function and cortex excitability in subacute stroke patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>Randomized controlled trial.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting:<\/jats:title>\n                    <jats:p>Inpatient hospitals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Subjects:<\/jats:title>\n                    <jats:p>\n                      Sixty-five participants were randomly assigned to four groups: sham, 1Hz rTMS, cathodic tDCS combined with 1Hz rTMS (tDCS\n                      <jats:sup>-<\/jats:sup>\n                      \/rTMS\n                      <jats:sup>-<\/jats:sup>\n                      ) and anodic tDCS combined with 1Hz rTMS (tDCS\n                      <jats:sup>+<\/jats:sup>\n                      \/rTMS\n                      <jats:sup>-<\/jats:sup>\n                      ).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interventions:<\/jats:title>\n                    <jats:p>Four interventions were used, including sham, 1Hz rTMS, and cathodal or anodal tDCS, followed by 1Hz rTMS over contralesional motor cortex, which continued for four weeks.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main measures:<\/jats:title>\n                    <jats:p>Outcome measures were motor function and cortical excitability, evaluated by Fugl-Meyer Assessment, National Institutes of Health Stroke Scale and Barthel Index, resting Motion Threshold, Motor Evoked Potentials and Central Motor Conduction Time, assessed at baseline, four weeks and eight weeks.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      At four weeks after interventions, Fugl-Meyer Assessment lower limb change score in tDCS\n                      <jats:sup>+<\/jats:sup>\n                      \/rTMS\n                      <jats:sup>-<\/jats:sup>\n                      group was significantly larger than other three groups ( P &lt; 0.001). There were significant differences in bilateral Motor Evoked Potentials changes between tDCS\n                      <jats:sup>+<\/jats:sup>\n                      \/rTMS\n                      <jats:sup>-<\/jats:sup>\n                      group and sham group ( P &lt; 0.05). At eight weeks, compared to other groups, National Institutes of Health Stroke Scale ( P = 0.003), Barthel Index ( P = 0.002), FMA lower limb score ( P &lt; 0.001), and bilateral resting Motion Threshold, Motor Evoked Potentials ( P &lt; 0.05) showed significant changes in tDCS\n                      <jats:sup>+<\/jats:sup>\n                      \/rTMS\n                      <jats:sup>-<\/jats:sup>\n                      group. Furthermore, Fugl-Meyer Assessment lower limb change score was associated with increased ipsilesional Motor Evoked Potentials ( r = 0.703 P &lt; 0.001) in tDCS+\/rTMS- group.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>1Hz rTMS combined with anode tDCS stimulation protocol could be a preferable rehabilitative strategy for motor recovery in subacute stroke patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0269215520972940","type":"journal-article","created":{"date-parts":[[2020,11,23]],"date-time":"2020-11-23T04:25:22Z","timestamp":1606105522000},"page":"718-727","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":43,"title":["Effects of repetitive transcranial magnetic stimulation combined with transcranial direct current stimulation on motor function and cortex excitability in subacute stroke patients: A randomized controlled trial"],"prefix":"10.1177","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5473-290X","authenticated-orcid":false,"given":"Yan","family":"Gong","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China"},{"name":"Department of Physical Medicine and Rehabilitation, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, Jiangsu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xian-Ming","family":"Long","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, Jiangsu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiu-Ying","family":"Cai","sequence":"additional","affiliation":[{"name":"Department of Neurology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"Ye","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, 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