{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T20:24:09Z","timestamp":1792095849549,"version":"4.4.0"},"reference-count":33,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2020,12,14]],"date-time":"2020-12-14T00:00:00Z","timestamp":1607904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"CNPq\/Pibic"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Rehabil"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To investigate the effect of low-level laser therapy (LLLT) combined with exercise on shoulder pain and disability in patients with subacromial impingement syndrome (SIS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>Randomised controlled trial.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting:<\/jats:title>\n                    <jats:p>Pontifical Catholic University.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Subjects:<\/jats:title>\n                    <jats:p>We enrolled 120 subacromial impingement syndrome patients<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Intervention:<\/jats:title>\n                    <jats:p>Groups I ( n\u2009=\u200942), II ( n\u2009=\u200942) and III ( n\u2009=\u200936) were treated with Low-level laser therapy and exercise, exercise only and Low-level laser therapy only, respectively. Interventions were conducted three times a week for 8\u2009weeks.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main outcome measures:<\/jats:title>\n                    <jats:p>The primary outcome was the change in shoulder pain and disability index (SPADI). Secondary outcomes included changes in the numeric pain rating scale and medication intake.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Average ages of patients in groups I, II and III were 51.9\u2009\u00b1\u20098.7\u2009years, 56.0\u2009\u00b1\u200910.4\u2009years and 54.2\u2009\u00b1\u20097.1\u2009years, respectively. Pain scores at baseline ( P\u2009=\u20090.829), 2\u2009months ( P\u2009=\u20090.057) and 3\u2009months follow-ups ( p\u2009=\u20090.004) were 6.8 (4.7\u20137.7), 0.2 (0.0\u20130.5) and 0.3 (0.0\u20131.0) for group I; 6.6 (5.7\u20138.0), 0.5 (0.2\u20132.0) and 0.2 (0.0\u20133.3) for group II; and 6.5 (5.1\u20137.4), 2.4 (0.1\u20136.7) and 4.0 (2.0\u20135.0) for group III, respectively. SPADI scores at baseline ( P\u2009=\u20090.029), 2\u2009months ( P\u2009&lt;\u20090.001) and 3\u2009months follow-ups ( P\u2009=\u20090.001) were 60.8 (37.7\u201370.8), 3.8 (0.0\u201310.8) and 2.3 (0.8\u201310.8) for group I; 61.5 (41.5\u201371.5), 9.2 (3.8\u201329.2) and 14.2 (1.5\u201338.0) for the group II; and 73.3 (59.2\u201380.8), 34.2 (16.9\u201354.6) and 33.1 (22.3\u201349.2) for the group III, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Low-level laser therapy combined with exercises reduce pain intensity, improve shoulder function and reduces pain intensity and medication intake over 3\u2009months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical Trial Registration number:<\/jats:title>\n                    <jats:p>NCT 02725749<\/jats:p>\n                  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