{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T18:23:14Z","timestamp":1788891794500,"version":"build-2803163510"},"reference-count":37,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2021,1,20]],"date-time":"2021-01-20T00:00:00Z","timestamp":1611100800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100000896","name":"Coleman Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000896","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009157","name":"National Institute on Disability, Independent Living, and Rehabilitation Research","doi-asserted-by":"publisher","award":["H133G06055"],"award-info":[{"award-number":["H133G06055"]}],"id":[{"id":"10.13039\/100009157","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Rehabil"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To investigate an intensive asynchronous computer-based treatment delivered remotely with clinician oversight to people with aphasia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>Single-blind, randomized placebo-controlled trial.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting:<\/jats:title>\n                    <jats:p>Free-standing urban rehabilitation hospital.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants:<\/jats:title>\n                    <jats:p>Adults with aphasia (at least six months post-onset).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interventions:<\/jats:title>\n                    <jats:p>\n                      Experimental treatment was Web ORLA\n                      <jats:sup>\u00ae<\/jats:sup>\n                      (Oral Reading for Language in Aphasia) which provides repeated choral and independent reading aloud of sentences with a virtual therapist. Placebo was a commercially available computer game. Participants were instructed to practice 90\u2009minutes\/day, six days\/week for six weeks.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main measures:<\/jats:title>\n                    <jats:p>Change in Language Quotient of the Western Aphasia Battery-Revised from pre-treatment to post-treatment and pre-treatment to six weeks following the end of treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      32 participants (19 Web ORLA\n                      <jats:sup>\u00ae<\/jats:sup>\n                      , 13 Control) completed the intervention and post-treatment assessment; 27 participants (16 Web ORLA\n                      <jats:sup>\u00ae<\/jats:sup>\n                      , 11 Control) completed the follow-up assessment six weeks after treatment had ended. Web ORLA\n                      <jats:sup>\u00ae<\/jats:sup>\n                      treatment resulted in significant improvements in language performance from pre-treatment to immediately post-treatment ( X\u2009=\u20092.96; SD\u2009=\u20094.32; P\u2009&lt;\u20090.01; ES\u2009=\u20090.68) and from pre-treatment to six weeks following the end of treatment ( X\u2009=\u20094.53; SD\u2009=\u20093.16; P\u2009&lt;\u20090.001; ES\u2009=\u20091.43). There was no significant difference in the gain from pre-treatment to post-treatment for the Web ORLA\n                      <jats:sup>\u00ae<\/jats:sup>\n                      versus Control groups. However, the Web ORLA\n                      <jats:sup>\u00ae<\/jats:sup>\n                      group showed significantly greater gains at the six-week follow-up than the control group ( X\u2009=\u20092.70; SD\u2009=\u20091.01; P\u2009=\u20090.013; ES\u2009=\u20091.92).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>\n                      Results provide evidence for improved language outcomes following intensive, web-based delivery of ORLA\n                      <jats:sup>\u00ae<\/jats:sup>\n                      to individuals with chronic aphasia. Findings underscore the value of combining clinician oversight with the flexibility of asynchronous practice.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0269215520988475","type":"journal-article","created":{"date-parts":[[2021,1,20]],"date-time":"2021-01-20T22:53:10Z","timestamp":1611183190000},"page":"976-987","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":40,"title":["Web-based Oral Reading for Language in Aphasia (Web ORLA\n                    <sup>\u00ae<\/sup>\n                    ): A pilot randomized control trial"],"prefix":"10.1177","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3754-4450","authenticated-orcid":false,"given":"Leora R","family":"Cherney","sequence":"first","affiliation":[{"name":"Think and Speak Lab, Shirley Ryan AbilityLab, Chicago, IL, USA"},{"name":"Departments of Physical Medicine and Rehabilitation and Communication Sciences and 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