{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T23:55:56Z","timestamp":1792799756480,"version":"4.5.0"},"reference-count":27,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2023,4,17]],"date-time":"2023-04-17T00:00:00Z","timestamp":1681689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Medical Innovation Project of Fujian Provincial Health Commission","award":["2018-CXB-10"],"award-info":[{"award-number":["2018-CXB-10"]}]},{"name":"Key Laboratory of Cardio-Thoracic Surgery (Fujian Medical University), Fujian Province University.","id":[{"id":"https:\/\/ror.org\/050s6ns64","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Fujian Provincial Finance Special Project","award":["2021XH019"],"award-info":[{"award-number":["2021XH019"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Rehabil"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To determine the safety and efficacy of early postoperative mobilization in patients who have undergone surgical repair of acute type A aortic dissection.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Randomized controlled trial.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Heart Medical Center.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Subjects<\/jats:title>\n                    <jats:p>Seventy-seven patients with acute type A aortic dissection were assessed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Intervention<\/jats:title>\n                    <jats:p>Patients were randomly allocated into: (1) the control group (usual care) ( n\u2009\u2009=\u2009\u200938) and (2) the intervention group (early goal-directed mobilization) ( n\u2009\u2009=\u2009\u200939).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Measures<\/jats:title>\n                    <jats:p>The primary outcome was the patient's functional status. The secondary outcomes included vital signs, serious adverse events, muscle strength, intensive care unit-acquired weakness, grip strength, duration of mechanical ventilation, length of stay, readmission rate, and health-related quality of life after 3 months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The vital signs of the patients were within the tolerable ranges during the entire intervention. No serious exercise-related adverse events were observed in the intervention group. The Barthel Index score ( P\u2009\u2009=\u2009\u20090.013), Medical Research Council score ( P\u2009\u2009=\u2009\u20090.001), grip strength ( P\u2009\u2009=\u2009\u20090.001), and health-related quality of life ( P\u2009\u2009=\u2009\u20090.001) were higher in the intervention group. Intensive care unit acquired weakness ( P\u2009\u2009=\u2009\u20090.019), duration of mechanical ventilation ( P\u2009\u2009=\u2009\u20090.002), intensive care unit stay ( P\u2009\u2009=\u2009\u20090.002), and total length of stay ( P\u2009\u2009=\u2009\u20090.010) were lower in the intervention group. Patients in the intervention group had a higher physical health-related quality of life ( P\u2009\u2009=\u2009\u20090.015) at 3 months post-surgery. There was no difference in readmission rates.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Delivery of early goal-directed mobilization in acute type A aortic dissection was safe and facilitated the recovery of daily living ability, shorter hospital stay, and improved quality of life after discharge.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/02692155231169822","type":"journal-article","created":{"date-parts":[[2023,4,18]],"date-time":"2023-04-18T02:28:39Z","timestamp":1681784919000},"page":"1311-1321","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":19,"title":["Early goal-directed mobilization in patients with acute type A aortic dissection: A randomized controlled trial"],"prefix":"10.1177","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6890-7552","authenticated-orcid":false,"given":"Yanjuan","family":"Lin","sequence":"first","affiliation":[{"name":"Department of Nursing, Fujian Medical University Union Hospital, Fuzhou, Fujian, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting","family":"Liang","sequence":"additional","affiliation":[{"name":"Department of Nursing, Fujian Medical University, Fuzhou, Fujian, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xu","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Nursing, Women and Children's Hospital, School of Medicine, Xiamen University, Xiamen, Fujian, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanchun","family":"Peng","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sailan","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xizhen","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liangwan","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,4,17]]},"reference":[{"key":"bibr1-02692155231169822","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2020.07.061"},{"key":"bibr2-02692155231169822","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.117.031264"},{"key":"bibr3-02692155231169822","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000004181"},{"key":"bibr4-02692155231169822","doi-asserted-by":"publisher","DOI":"10.1186\/s12877-020-01823-1"},{"key":"bibr5-02692155231169822","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0223151"},{"key":"bibr6-02692155231169822","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11082107"},{"key":"bibr7-02692155231169822","first-page":"1","volume":"0","author":"Ambrosetti M","year":"2020","journal-title":"Eur J Prev 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