{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T16:06:24Z","timestamp":1791389184786,"version":"4.3.3"},"reference-count":36,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2024,10,3]],"date-time":"2024-10-03T00:00:00Z","timestamp":1727913600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Rehabil"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate the effectiveness of osteopathic manipulative treatment (OMT) associated with transcranial direct current stimulation (tDCS) in reducing pain, disability, and improving quality of life in participants with non-specific chronic low back pain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>A randomised double-blind clinical trial.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Clinical outpatient unit.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Subjects<\/jats:title>\n                    <jats:p>72 participants with non-specific chronic low back pain were randomised into three groups: active tDCS + OMT ( n = 24), sham tDCS + sham OMT ( n = 24), and sham tDCS + OMT ( n = 24).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interventions<\/jats:title>\n                    <jats:p>Evaluations were performed before, after the intervention, and one month post-intervention. tDCS consisted of ten 20-minute sessions over two weeks (five sessions per week). OMT was administered once per week, with two sessions conducted before the first and sixth tDCS sessions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main measures<\/jats:title>\n                    <jats:p>Pain, disability, and quality of life were assessed at baseline, after two weeks, and at one month of follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The visual analogue scale showed a significant decrease in all groups ( p &lt; 0.001). However, tDCS + OMT and sham tDCS + OMT demonstrated a clinically significant reduction compared to the sham combination (effect size n\u00b2 = 0.315). Roland-Morris scores decreased across all groups without specific group effects. EuroQoL 5-Dimension 3-Level improvement was observed only in the tDCS + OMT and sham tDCS + OMT groups (significant difference between T2 and T0, p = 0.002).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The combination of OMT and tDCS did not provide clinically significant improvement over OMT alone in participants with non-specific chronic low back pain.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/02692155241274718","type":"journal-article","created":{"date-parts":[[2024,10,3]],"date-time":"2024-10-03T20:22:28Z","timestamp":1727986948000},"page":"1609-1621","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":12,"title":["Effects of osteopathic manipulative treatment associated with transcranial direct current stimulation in individuals with chronic low back pain: A double-blind, randomised placebo-controlled trial"],"prefix":"10.1177","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7387-5559","authenticated-orcid":false,"given":"Danilo","family":"Armbrust","sequence":"first","affiliation":[{"name":"Santa Casa School of Medical Sciences of S\u00e3o Paulo, S\u00e3o Paulo, Brazil"},{"name":"Department of Physiotherapy, Faculty Anhanguera of Sorocaba, Sorocaba, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guilherme Peixoto Tinoco","family":"Ar\u00eaas","sequence":"additional","affiliation":[{"name":"Physiology Department, Federal University of Amazonas, Manaus, Amazonas, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos Luques","family":"Fonseca","sequence":"additional","affiliation":[{"name":"Santa Casa School of Medical Sciences of S\u00e3o Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2068-2606","authenticated-orcid":false,"given":"Fernando Zanela da Silva","family":"Ar\u00eaas","sequence":"additional","affiliation":[{"name":"Federal University of Esp\u00edrito Santo, Esp\u00edrito Santo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nat\u00e1lia de Almeida Carvalho","family":"Duarte","sequence":"additional","affiliation":[{"name":"University Center of An\u00e1polis, An\u00e1polis, Goi\u00e1s, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia Ata\u00edde Alves","family":"Santana","sequence":"additional","affiliation":[{"name":"Physiology Department, Federal University of Amazonas, Manaus, Amazonas, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8851-2769","authenticated-orcid":false,"given":"Arislander Jonathan 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