{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T07:10:23Z","timestamp":1777533023161,"version":"3.51.4"},"reference-count":23,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2025,4,28]],"date-time":"2025-04-28T00:00:00Z","timestamp":1745798400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Rehabil"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate changes in mobility in adults with recent major lower limb amputation participating in community-based rehabilitation. Second, to assess the impact of amputation level (transtibial versus transfemoral) on mobility changes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Cohort study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Rehabilitation Centre in Copenhagen Municipality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Subjects<\/jats:title>\n                    <jats:p>A total of 265 individuals with recent major lower limb amputations were prospectively recruited into a cohort from 2008 to 2022 as part of routine practice.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Four physiotherapists collected data on age, sex, level of amputation (transtibial\/transfemoral) and assessed mobility at start of walking out of parallel handrail (baseline) and at the end (follow-up) of rehabilitation. Mobility was assessed with the Timed-Up-and-Go test, 10-Meter Walk test, and 2-Minute Walk test. The impact of amputation level was analyzed using multivariable linear regression adjusted for age and sex.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 199 individuals (153 men) mean age of 64.9 (standard deviation 12.2) years had baseline and follow-up mobility data and were eligible for the study. Mobility significantly improved on all tests for individuals with both amputation levels after community rehabilitation. Multivariable analysis showed that individuals with transfemoral amputations on average improved with 17.9 seconds more (95% confidence interval: 12.7\u201323.1) than transtibial completing the Timed-Up-and-Go test. Contrary, transtibial walked 0.11 meter\/second faster (95% confidence interval: 0.02\u20130.20) and 7.2 meters (95% confidence interval: \u22121.4 to 15.8) longer in the 10-Meter Walk test and 2-Minute Walk test respectively than transfemoral amputees.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Adults with lower limb amputations improved their mobility signi\ufb01cantly from baseline to follow-up. Individuals with transfemoral amputations improved more than transtibial amputations on functional mobility.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/02692155251336566","type":"journal-article","created":{"date-parts":[[2025,4,28]],"date-time":"2025-04-28T03:09:12Z","timestamp":1745809752000},"page":"967-975","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Changes in mobility after community-based prosthesis fitting and rehabilitation in people with major lower limb amputations: a cohort study"],"prefix":"10.1177","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5432-8691","authenticated-orcid":false,"given":"Inger","family":"Mechlenburg","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, Aarhus University Hospital, Aarhus, Denmark"},{"name":"Department of Clinical Medicine, Aarhus University, Aarhus, Denmark"},{"name":"Department of Public Health, Aarhus University, Aarhus, Denmark"},{"name":"Research Center for Activity and Prevention, VIA University College, Aarhus N, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4666-4622","authenticated-orcid":false,"given":"Lisa Urup","family":"T\u00f8nning","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Aarhus University Hospital, Aarhus, Denmark"},{"name":"Department of Clinical Medicine, Aarhus University, Aarhus, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rikke","family":"\u00d8rholst","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Aarhus University Hospital, Aarhus, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cecilie","family":"Iversen","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Aarhus University Hospital, Aarhus, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kajsa","family":"Lindberg","sequence":"additional","affiliation":[{"name":"Health and Rehabilitation Centre Vanl\u00f8se, Copenhagen Municipality, Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Morten Tange","family":"Kristensen","sequence":"additional","affiliation":[{"name":"Department of Physical and Occupational Therapy, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark"},{"name":"Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,4,28]]},"reference":[{"key":"e_1_3_3_2_2","volume-title":"Kortl\u00e6gning af regionale og kommunale tilbud om rehabilitering til personer der f\u00e5r amputeret ben i Danmark","author":"Mars\u00e5 URMTVATBMA-DOZK","year":"2021","unstructured":"Mars\u00e5 URMTVATBMA-DOZK. Kortl\u00e6gning af regionale og kommunale tilbud om rehabilitering til personer der f\u00e5r amputeret ben i Danmark. Nyborg, Denmark: REHPA, Videncenter for Rehabilitering og Palliation, 2021. www.rehpa.dk."},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/icvts\/ivr075"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1080\/09638288.2023.2240231"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2017-016030"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/jocn.13716"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/ggi.14874"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2017.12.033"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arrct.2020.100084"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2010.12.097"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1682\/JRRD.2014.09.0210"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.3109\/03093649509167999"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD005260.pub3"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.0040297"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1093\/ptj\/pzy107"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1519\/00139143-200831020-00003"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1519\/JPT.0000000000000080"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2019.06.021"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.284.6329.1607"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12955-018-1055-z"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pmrj.2015.05.006"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1080\/17483107.2019.1684581"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12603-009-0246-z"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1097\/00002281-200209000-00017"}],"container-title":["Clinical Rehabilitation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02692155251336566","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/02692155251336566","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02692155251336566","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T16:50:54Z","timestamp":1777395054000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/02692155251336566"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,28]]},"references-count":23,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["10.1177\/02692155251336566"],"URL":"https:\/\/doi.org\/10.1177\/02692155251336566","relation":{},"ISSN":["0269-2155","1477-0873"],"issn-type":[{"value":"0269-2155","type":"print"},{"value":"1477-0873","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,28]]}}}