{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T18:05:53Z","timestamp":1777917953239,"version":"3.51.4"},"reference-count":15,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T00:00:00Z","timestamp":1527811200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100001027","name":"Department of Health and Ageing, Australian Government","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001027","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Palliat Med"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Translating research evidence into clinical practice often has a long lag time.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>To determine the impact of a phase III randomised controlled trial on palliative care clinicians\u2019 self-reported practice change.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>Online survey about use of octreotide in managing inoperable malignant bowel obstruction due to cancer or its treatments distributed in November 2016, 2\u2009years after the first publication of the study in a peer-reviewed journal. Demographic, self-reported practice and the reasons underpinning this were collected. Responses were aggregated to \u2018practice modified\u2019 or \u2018practice not modified\u2019. A multinomial regression model explored predictors of practice change.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting:<\/jats:title>\n                    <jats:p>Members of the Australian New Zealand Society of Palliative Medicine.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Response rate was 20.8% (106\/509): 55.6% were aged &gt;50\u2009years, 56.5% were female and 77% had previously prescribed octreotide for this clinical indication. Out of 106 respondents, 52 (49.1%) indicated modified practice (60.9% of those who had previously prescribed octreotide in this setting). In those who reported practice change, most frequently octreotide was now used when other therapies failed; for not changing practice, \u2018more confirmatory evidence was needed\u2019 was most often cited. In the regression model, older age (clinician age\u2009=\u200950\u201359\u2009years; relative risk\u2009=\u20090.147; 95% confidence interval\u2009=\u20090.024\u20130.918; p\u2009=\u20090.04) and having practices with lower proportions of people treated with octreotide (0%\u201320%; relative risk\u2009=\u20090.039; 95% confidence interval\u2009=\u20090.002\u20130.768; p\u2009=\u20090.033) predicted greater self-reported practice change.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Clinician-reported change in practice in the survey is seen in the majority of respondents. This suggests that there is a cohort of \u2018early adopters\u2019 within palliative care practice as new evidence becomes available.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0269216318778460","type":"journal-article","created":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T11:15:06Z","timestamp":1527851706000},"page":"1363-1368","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Clinician-reported changes in octreotide prescribing for malignant bowel obstruction as a result of an adequately powered phase III study: A transnational, online survey"],"prefix":"10.1177","volume":"32","author":[{"given":"Rachel","family":"Campbell","sequence":"first","affiliation":[{"name":"Flinders Medical Centre, Bedford Park, SA, Australia"},{"name":"Marie Curie Hospice, Belfast, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikki","family":"McCaffrey","sequence":"additional","affiliation":[{"name":"Deakin Health Economics, Centre for Population Health Research, School of Health and Social Development, Deakin University, Geelong, VIC, Australia"},{"name":"Improving Palliative, Aged and Chronic Care through Clinical Research and Translation (IMPACCT), Faculty of Health, University of Technology Sydney, Ultimo, NSW, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda","family":"Brown","sequence":"additional","affiliation":[{"name":"Improving Palliative, Aged and Chronic Care through Clinical Research and Translation (IMPACCT), Faculty of Health, University of Technology Sydney, Ultimo, NSW, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meera R","family":"Agar","sequence":"additional","affiliation":[{"name":"Improving Palliative, Aged and Chronic Care through Clinical Research and Translation (IMPACCT), Faculty of Health, University of Technology Sydney, Ultimo, NSW, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katherine","family":"Clark","sequence":"additional","affiliation":[{"name":"Northern Sydney Local Health District Cancer and Palliative Care Network, Royal North Shore Hospital, St Leonards, NSW, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1988-1250","authenticated-orcid":false,"given":"David C","family":"Currow","sequence":"additional","affiliation":[{"name":"Improving Palliative, Aged and Chronic Care through Clinical Research and Translation (IMPACCT), Faculty of Health, University of Technology Sydney, Ultimo, NSW, Australia"},{"name":"Wolfson Palliative Care Research Centre, University of Hull, Hull, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2018,6,1]]},"reference":[{"key":"bibr1-0269216318778460","first-page":"CD000259","volume":"13","author":"Ivers N","year":"2012","journal-title":"Cochrane Database Syst Rev"},{"key":"bibr2-0269216318778460","first-page":"CD003030","volume":"2009","author":"Forsetlund L","year":"2009","journal-title":"Cochrane Database Syst Rev"},{"key":"bibr3-0269216318778460","first-page":"CD000125","volume":"2011","author":"Flodgren G","year":"2011","journal-title":"Cochrane Database Syst Rev"},{"key":"bibr4-0269216318778460","doi-asserted-by":"publisher","DOI":"10.1258\/jrsm.2011.110180"},{"key":"bibr5-0269216318778460","doi-asserted-by":"publisher","DOI":"10.2147\/CMAR.S29297"},{"key":"bibr6-0269216318778460","first-page":"CD001219","volume":"2000","author":"Feuer DJ","year":"2000","journal-title":"Cochrane Database Syst Rev"},{"key":"bibr7-0269216318778460","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-009-0609-3"},{"key":"bibr8-0269216318778460","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2014.09.013"},{"key":"bibr9-0269216318778460","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2016.05.032"},{"key":"bibr10-0269216318778460","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2014.07.013"},{"key":"bibr11-0269216318778460","doi-asserted-by":"publisher","DOI":"10.2196\/jmir.6.3.e34"},{"key":"bibr12-0269216318778460","unstructured":"Australian Institute of Health Welfare (AIHW). Medical practitioners workforce summary, 2015, https:\/\/www.aihw.gov.au\/getmedia\/34c49f50-8433-4373-8306-699fd2745958\/Palliative-care-workforce.pdf.aspx (accessed 7 January 2018)."},{"key":"bibr13-0269216318778460","doi-asserted-by":"publisher","DOI":"10.1071\/AH15012"},{"key":"bibr14-0269216318778460","doi-asserted-by":"publisher","DOI":"10.7326\/M15-1330"},{"key":"bibr15-0269216318778460","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2016.10.358"}],"container-title":["Palliative Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0269216318778460","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0269216318778460","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0269216318778460","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T18:27:08Z","timestamp":1777660028000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0269216318778460"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6,1]]},"references-count":15,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2018,9]]}},"alternative-id":["10.1177\/0269216318778460"],"URL":"https:\/\/doi.org\/10.1177\/0269216318778460","relation":{},"ISSN":["0269-2163","1477-030X"],"issn-type":[{"value":"0269-2163","type":"print"},{"value":"1477-030X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,6,1]]}}}