{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T18:07:37Z","timestamp":1777918057507,"version":"3.51.4"},"reference-count":13,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2020,3,18]],"date-time":"2020-03-18T00:00:00Z","timestamp":1584489600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Faculty of Health at Witten\/Herdecke University, Germany.","award":["project IFF 2017-16"],"award-info":[{"award-number":["project IFF 2017-16"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Palliat Med"],"published-print":{"date-parts":[[2020,6]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Multidrug-resistant organisms are a growing challenge and burden to patient care. To date, there are only data concerning the prevalence of methicillin-resistant Staphylococcus aureus infections. Thus, numbers of other multidrug-resistant organisms can only be extrapolated and inferred from more or less comparable cohorts.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>To evaluate the prevalence of multidrug-resistant organisms on palliative care in-patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>A prospective cohort analysis<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting\/participants:<\/jats:title>\n                    <jats:p>A University Hospital\u2013bound palliative care unit, in which all patients admitted to the unit were screened for inclusion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>In total, 304 patients were included in this study. The prevalence for methicillin-resistant Staphylococcus aureus of 5.2% (95% confidence interval: 2.9%\u20138.4%), for vancomycin-resistant Enterococcus faecium of 10.5% (95% confidence interval: 7.2%\u201314.8%), for Ciprofloxacin-resistant-extended spectrum beta-lactamases isolates of 5.8% (95% confidence interval: 3.4%\u20139.3%) and Ciprofloxacin-resistant Carbapenem-resistant Gram-negative bacteria of 0.3% (95% confidence interval: 0%\u20131.3%) was calculated. Except for methicillin-resistant Staphylococcus aureus, patients carrying a multidrug-resistant organism had a significant longer duration of hospitalization. Median length of stay was 12\u2009days (interquartile range: 14.5, no multidrug-resistant organisms), 14.5\u2009days (interquartile range: 15, methicillin-resistant Staphylococcus aureus), 21\u2009days (interquartile range: 16.5, vancomycin-resistant enterococci), 22\u2009days (interquartile range: 20.75, Ciprofloxacin-resistant-extended spectrum beta-lactamases) and 32\u2009days (interquartile range: 22.00) for patients carrying two organisms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>There is a high prevalence of all multidrug-resistant organisms within the hospitalized palliative care patients. However, the multidrug-resistant organisms do not seem to impact the survival within this cohort. Further studies should evaluate additional end-points, for example, quality of life, which are of special interest in this cohort.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0269216320911591","type":"journal-article","created":{"date-parts":[[2020,3,18]],"date-time":"2020-03-18T09:41:37Z","timestamp":1584524497000},"page":"776-783","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Prevalence of multidrug-resistant organisms on palliative care patients in a university hospital\u2013bound palliative care unit: A prospective cohort analysis"],"prefix":"10.1177","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7737-5466","authenticated-orcid":false,"given":"Tobias Georg","family":"Strapatsas","sequence":"first","affiliation":[{"name":"Faculty of Health, Witten\/Herdecke University, Witten, Germany"},{"name":"Department of Emergency Medicine, M\u00f6nchengladbach Municipal Hospital, M\u00f6nchengladbach, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Viola","family":"Simons","sequence":"additional","affiliation":[{"name":"Medical Clinic 1, Division of Oncology and Palliative Care, HELIOS Klinikum Wuppertal, Wuppertal, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beniam","family":"Ghebremedhin","sequence":"additional","affiliation":[{"name":"Institute for Medical Laboratory Diagnostics, Center for Clinical and Translational Research, HELIOS University Hospital Wuppertal, Witten\/Herdecke University, Wuppertal, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Parviz","family":"Ahmad-Nejad","sequence":"additional","affiliation":[{"name":"Institute for Medical Laboratory Diagnostics, Center for Clinical and Translational Research, HELIOS University Hospital Wuppertal, Witten\/Herdecke University, Wuppertal, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oliver","family":"Schmalz","sequence":"additional","affiliation":[{"name":"Medical Clinic 1, Division of Oncology and Palliative Care, HELIOS Klinikum Wuppertal, Wuppertal, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,3,18]]},"reference":[{"key":"bibr1-0269216320911591","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1186\/s12879-017-2271-6","volume":"17","author":"Walter J","year":"2017","journal-title":"BMC Infect Dis"},{"key":"bibr2-0269216320911591","doi-asserted-by":"publisher","DOI":"10.1177\/1049909112452335"},{"key":"bibr3-0269216320911591","doi-asserted-by":"publisher","DOI":"10.1177\/0269216316637772"},{"key":"bibr4-0269216320911591","doi-asserted-by":"publisher","DOI":"10.1177\/0269216315595158"},{"key":"bibr5-0269216320911591","doi-asserted-by":"publisher","DOI":"10.1089\/jpm.2016.0301"},{"key":"bibr6-0269216320911591","doi-asserted-by":"publisher","DOI":"10.1177\/1178224217749233"},{"key":"bibr7-0269216320911591","doi-asserted-by":"publisher","DOI":"10.1177\/0269216315622125"},{"key":"bibr8-0269216320911591","doi-asserted-by":"publisher","DOI":"10.1177\/0269216311425709"},{"key":"bibr9-0269216320911591","doi-asserted-by":"publisher","DOI":"10.1097\/01.SMJ.0000050683.36014.2E"},{"key":"bibr10-0269216320911591","volume-title":"R: a language and environment for statistical computing","author":"R Core Team","year":"2018"},{"key":"bibr11-0269216320911591","unstructured":"Wickham H. 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