{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T06:15:06Z","timestamp":1790835306587,"version":"4.1.0"},"reference-count":53,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2020,6,10]],"date-time":"2020-06-10T00:00:00Z","timestamp":1591747200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1065571"],"award-info":[{"award-number":["APP1065571"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Palliat Med"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Chronic breathlessness is a disabling syndrome that profoundly impacts patients\u2019 and caregivers\u2019 lives. Driving is important for most people, including those with advanced disease. Regular, low-dose, sustained-release morphine safely reduces breathlessness, but little is known about its impact on driving.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>To understand patients\u2019 and caregivers\u2019 (1) perspectives and experiences of driving with chronic breathlessness; and (2) perceived impact of regular, low-dose, sustained-release morphine on driving.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>A qualitative study embedded in a pragmatic, phase III, randomised, placebo-controlled trial of low-dose, sustained-release morphine (\u2a7d32\u2009mg\/24\u2009h) for chronic breathlessness. Semi-structured interviews were conducted immediately after participants withdrew or completed the randomised, placebo-controlled trial. Informed by grounded theory, a constant comparative approach to analysis was adopted.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting\/participants:<\/jats:title>\n                    <jats:p>Participants were recruited from an outpatients palliative care service in Adelaide, Australia. Participants included patients ( n\u2009=\u200913) with severe breathlessness associated with chronic obstructive pulmonary disease and their caregivers ( n\u2009=\u20099).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Participants were interviewed at home. Eleven received morphine 8\u201332\u2009mg. Three themes emerged: (1) independence; (2) breathlessness\u2019 impact on driving; and (3) driving while taking regular, low-dose, sustained-release morphine.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Driving contributed to a sense of identity and independence. Being able to drive increased the physical and social space available to patients and caregivers, their social engagement and well-being. Patients reported breathlessness at rest may impair driving skills, while the introduction of sustained-release morphine seemed to have no self-reported impact on driving. Investigating this last perception objectively, especially in terms of safety, is the subject of ongoing work.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0269216320929549","type":"journal-article","created":{"date-parts":[[2020,6,10]],"date-time":"2020-06-10T05:24:05Z","timestamp":1591766645000},"page":"1078-1087","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Patients\u2019 and caregivers\u2019 experiences of driving with chronic breathlessness before and after regular low-dose sustained-release morphine: A qualitative study"],"prefix":"10.1177","volume":"34","author":[{"given":"Diana H","family":"Ferreira","sequence":"first","affiliation":[{"name":"Palliative and Supportive Services, Flinders University, Bedford Park, SA, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5272-3057","authenticated-orcid":false,"given":"Jason W","family":"Boland","sequence":"additional","affiliation":[{"name":"Wolfson Palliative Care Research Centre, Hull York Medical School, University of Hull, Hull, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Slavica","family":"Kochovska","sequence":"additional","affiliation":[{"name":"IMPACCT, Faculty of Health, University of Technology Sydney, Ultimo, NSW, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aaron","family":"Honson","sequence":"additional","affiliation":[{"name":"Palliative and Supportive Services, Flinders University, Bedford Park, SA, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3691-8230","authenticated-orcid":false,"given":"Jane L","family":"Phillips","sequence":"additional","affiliation":[{"name":"IMPACCT, Faculty of Health, University of Technology Sydney, Ultimo, NSW, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1988-1250","authenticated-orcid":false,"given":"David C","family":"Currow","sequence":"additional","affiliation":[{"name":"Palliative and Supportive Services, Flinders University, Bedford Park, SA, Australia"},{"name":"Wolfson Palliative Care Research Centre, Hull York Medical School, University of Hull, Hull, UK"},{"name":"IMPACCT, Faculty of Health, University of Technology Sydney, Ultimo, NSW, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,6,10]]},"reference":[{"key":"bibr1-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.02277-2016"},{"key":"bibr2-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2009.01.006"},{"key":"bibr3-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2005.06.007"},{"key":"bibr4-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1136\/thoraxjnl-2016-209908"},{"key":"bibr5-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1378\/chest.121.5.1434"},{"key":"bibr6-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2702.2008.01005.x"},{"key":"bibr7-0269216320929549","doi-asserted-by":"publisher","DOI":"10.12968\/ijpn.2008.14.11.31756"},{"key":"bibr8-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1111\/nhs.12073"},{"key":"bibr9-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1177\/1471301218762838"},{"key":"bibr10-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/60.3.399"},{"key":"bibr11-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.13931"},{"key":"bibr12-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1186\/2193-1801-3-79"},{"key":"bibr13-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1177\/0269216318773956"},{"key":"bibr14-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2010.11.021"},{"key":"bibr15-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1513\/AnnalsATS.201501-034OC"},{"key":"bibr16-0269216320929549","unstructured":"Australian Public Assessment Report for morphine sulphate pentahydrate\n                      . Report PM-2017-01592-1-5 FINAL 21, March 2019. MaynePharma International Pty Ltd, https:\/\/www.tga.gov.au\/sites\/default\/files\/auspar-morphine-sulfate-pentahydrate-190321.pdf (accessed 30 January 2020)."},{"key":"bibr17-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1080\/09687637.2017.1344620"},{"key":"bibr18-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1177\/0269216317746583"},{"key":"bibr19-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2017-018100"},{"key":"bibr20-0269216320929549","doi-asserted-by":"publisher","DOI":"10.31887\/DCNS.2011.13.2\/npatsopoulos"},{"key":"bibr21-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9681(67)90041-0"},{"key":"bibr22-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1002\/pon.1725"},{"key":"bibr23-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1136\/thx.54.7.581"},{"key":"bibr24-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1093\/occmed\/kqm162"},{"key":"bibr25-0269216320929549","doi-asserted-by":"publisher","DOI":"10.12968\/ijpn.2015.21.11.557"},{"key":"bibr26-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1016\/j.pec.2012.11.007"},{"key":"bibr27-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2288-9-47"},{"key":"bibr28-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1097\/00006199-196807000-00014"},{"key":"bibr29-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1080\/17482620600858399"},{"key":"bibr30-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1023\/A:1020909529486"},{"key":"bibr31-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1089\/jpm.2010.0050"},{"key":"bibr32-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1093\/intqhc\/mzm042"},{"key":"bibr33-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1016\/j.tra.2006.05.004"},{"key":"bibr34-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1080\/01634372.2010.522231"},{"key":"bibr35-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2702.2002.00651.x"},{"key":"bibr36-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2648.2010.05604.x"},{"key":"bibr37-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1177\/082585971102700302"},{"key":"bibr38-0269216320929549","doi-asserted-by":"publisher","DOI":"10.2147\/COPD.S139188"},{"key":"bibr39-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpain.2010.09.008"},{"key":"bibr40-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/297371"},{"key":"bibr41-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1017\/S1041610215001441"},{"key":"bibr42-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.111758"},{"key":"bibr43-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1177\/1479972315571926"},{"key":"bibr44-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1097\/SPC.0000000000000281"},{"key":"bibr45-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1111\/imj.13571"},{"key":"bibr46-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3959(94)00204-R"},{"key":"bibr47-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1016\/j.aap.2005.03.002"},{"key":"bibr48-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1016\/j.trf.2010.11.011"},{"key":"bibr49-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1017\/S0714980816000015"},{"key":"bibr50-0269216320929549","doi-asserted-by":"publisher","DOI":"10.3390\/geriatrics1010006"},{"key":"bibr51-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1016\/j.pmn.2003.11.002"},{"key":"bibr52-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2019.10.022"},{"key":"bibr53-0269216320929549","doi-asserted-by":"publisher","DOI":"10.1136\/bmjresp-2015-000092"}],"container-title":["Palliative Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0269216320929549","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0269216320929549","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0269216320929549","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T18:30:02Z","timestamp":1777660202000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0269216320929549"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,10]]},"references-count":53,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2020,9]]}},"alternative-id":["10.1177\/0269216320929549"],"URL":"https:\/\/doi.org\/10.1177\/0269216320929549","relation":{},"ISSN":["0269-2163","1477-030X"],"issn-type":[{"value":"0269-2163","type":"print"},{"value":"1477-030X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,6,10]]}}}