{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T18:09:35Z","timestamp":1777918175681,"version":"3.51.4"},"reference-count":5,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2022,2,17]],"date-time":"2022-02-17T00:00:00Z","timestamp":1645056000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Palliat Med"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Severe, cancer-related facial oedema can impair vision. It can result from lymphatic and\/or venous obstruction due to disease and\/or treatment related fibrosis. There is very limited data on the use of directly applied hypertonic packs for the relief of periorbital oedema.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case:<\/jats:title>\n                    <jats:p>A 63\u2009year old man with recurrent laryngeal squamous cell carcinoma developed functional blindness secondary to periorbital oedema in the setting of severe facial swelling. This was refractory to maximal facial lymphatic massage available in the community setting.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Possible courses of action:<\/jats:title>\n                    <jats:p>Management dilemmas included what non-medical interventions may relieve his periorbital oedema and thereby restore his vision outside of daily lymphatic massage from a qualified physiotherapist.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Formulation of management plan:<\/jats:title>\n                    <jats:p>The patient agreed to an initial dry hypertonic pack with a great functional improvement of his vision. He was taught how to do this so that he could repeat ad libitum.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Outcome:<\/jats:title>\n                    <jats:p>The patient had previously expressed that his most distressing thought was the prospect of becoming functionally blind prior to dying. The provision of an easy additional therapy to relieve his visual obstruction provided him with much comfort. He passed away peacefully a few weeks later.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Lessons:<\/jats:title>\n                    <jats:p>The case demonstrates that application of a dry hypertonic pack can relieve periorbital oedema in the setting of facial oedema in cases which are refractory to the combination of self-massage, cold-compress application, and daily lymphatic massage by a certified physiotherapist.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Research avenues:<\/jats:title>\n                    <jats:p>A case series to define incidence of adverse effects and duration of treatment effectiveness.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/02692163211069768","type":"journal-article","created":{"date-parts":[[2022,2,18]],"date-time":"2022-02-18T00:02:32Z","timestamp":1645142552000},"page":"555-559","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Hypertonic packs to reverse blindness caused by facial lymphoedema in the setting of head and neck cancer \u2013 A case report"],"prefix":"10.1177","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9695-9109","authenticated-orcid":false,"given":"Taylan","family":"Gurgenci","sequence":"first","affiliation":[{"name":"Department of Palliative Care, St Vincent\u2019s Private Hospital, Brisbane, QLD, Australia"},{"name":"Faculty of Medicine, The University of Queensland, Saint Lucia, QLD, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosalind","family":"Cree","sequence":"additional","affiliation":[{"name":"Department of Palliative Care, St Vincent\u2019s Private Hospital, Brisbane, QLD, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melissa","family":"Jessop","sequence":"additional","affiliation":[{"name":"Department of Palliative Care, St Vincent\u2019s Private Hospital, Brisbane, QLD, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan","family":"Lomas","sequence":"additional","affiliation":[{"name":"Department of Ear Nose and Throat Surgery, Toowoomba Hospital, Queensland Health, Brisbane, QLD, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Phillip","family":"Good","sequence":"additional","affiliation":[{"name":"Department of Palliative Care, St Vincent\u2019s Private Hospital, Brisbane, QLD, Australia"},{"name":"Mater Research Institute, The University of Queensland, South Brisbane, QLD, Australia"},{"name":"Department of Palliative Care, Mater Health Services, Brisbane, QLD, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,2,17]]},"reference":[{"issue":"4","key":"bibr1-02692163211069768","first-page":"676","volume":"8","author":"O\u2019Donnell TF","year":"2020","journal-title":"JVS Venous"},{"key":"bibr2-02692163211069768","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2019.05.024"},{"key":"bibr3-02692163211069768","doi-asserted-by":"publisher","DOI":"10.1097\/MOO.0b013e3283393799"},{"key":"bibr4-02692163211069768","doi-asserted-by":"publisher","DOI":"10.1002\/pon.4884"},{"issue":"1","key":"bibr5-02692163211069768","first-page":"72","volume":"5","author":"Towers A","year":"2010","journal-title":"J Lymphoedema"}],"container-title":["Palliative Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02692163211069768","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/02692163211069768","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02692163211069768","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T18:32:50Z","timestamp":1777660370000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/02692163211069768"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2,17]]},"references-count":5,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,3]]}},"alternative-id":["10.1177\/02692163211069768"],"URL":"https:\/\/doi.org\/10.1177\/02692163211069768","relation":{},"ISSN":["0269-2163","1477-030X"],"issn-type":[{"value":"0269-2163","type":"print"},{"value":"1477-030X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,2,17]]}}}