{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T18:12:34Z","timestamp":1777918354095,"version":"3.51.4"},"reference-count":33,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2024,12,17]],"date-time":"2024-12-17T00:00:00Z","timestamp":1734393600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Mesothelioma UK","award":["Mesothelioma UK (MUK) 2021 Grant Award"],"award-info":[{"award-number":["Mesothelioma UK (MUK) 2021 Grant Award"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Palliat Med"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Pleural mesothelioma is a rare and incurable cancer, with complex physical and psychological symptoms. Despite recent advances in treatment, prognosis remains poor (average 8\u201315\u2009months) with a lack of research on palliative and end-of-life care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>To examine markers suggestive of quality palliative and end-of-life care, including receipt of specialist palliative care, advance care planning, fewer unplanned hospital admissions at end-of-life. To compare variables with socio-economic position to identify if inequalities exist.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>A cohort study, retrospectively reviewing the medical notes from diagnosis to death for all patients diagnosed with pleural mesothelioma between 01\/01\/2016 and 31\/12\/2021.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting\/participants:<\/jats:title>\n                    <jats:p>Over 5\u2009years, n\u2009=\u2009181 patients were diagnosed with pleural mesothelioma across Teesside (north-east England), n\u2009=\u200930 were alive at study commencement and excluded. For the 151-patient cohort, demographics were as follows: 92% male, 79% aged 70\u201389\u2009years and 26% in the lowest socio-economic quintile (based on area-level deprivation).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Median survival was 246\u2009days. Within the final 90\u2009days of life, 69% of patients had at least 1 unplanned hospital admission, with 20% having 3+ (range 0\u20137). Those with the highest socio-economic position had less admissions on average. Specialist palliative care was received by patients, at home 34%, in hospital 26%, in hospice 11%. Do Not Attempt Cardiopulmonary Resuscitation (DNACPR) decisions, were in the final 24\u2009h of life for 18% of patients (median 7\u2009days). Disease specific findings included police attendance for expected deaths and lack of signposting.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Patients with pleural mesothelioma have unplanned admissions to hospital towards the end of life, with possible inequalities; they receive late advance care planning and face challenges unique to their disease. It is important that patients receive high quality palliative end-of-life care through accessing specialist palliative care or have guidance\/signposting to other potential sources of support.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/02692163241302454","type":"journal-article","created":{"date-parts":[[2024,12,17]],"date-time":"2024-12-17T03:25:07Z","timestamp":1734405907000},"page":"286-297","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Palliative and end-of-life care for patients with pleural mesothelioma: A cohort study"],"prefix":"10.1177","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6811-1255","authenticated-orcid":false,"given":"Donna","family":"Wakefield","sequence":"first","affiliation":[{"name":"North Tees & Hartlepool NHS Foundation Trust, Stockton-On-Tees, Stockton, UK"},{"name":"Population Health Sciences Institute, Faculty of Medical Sciences, Newcastle University, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tom","family":"Ward","sequence":"additional","affiliation":[{"name":"South Tees Hospitals NHS Foundation Trust, Middlesbrough, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-5926-605X","authenticated-orcid":false,"given":"Hannah","family":"Edge","sequence":"additional","affiliation":[{"name":"South Tees Hospitals NHS Foundation Trust, Middlesbrough, UK"},{"name":"Teesside Hospice, Middlesbrough, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1440-9953","authenticated-orcid":false,"given":"Catriona R","family":"Mayland","sequence":"additional","affiliation":[{"name":"The University of Sheffield, Sheffield, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1785-7054","authenticated-orcid":false,"given":"Clare","family":"Gardiner","sequence":"additional","affiliation":[{"name":"The University of Sheffield, Sheffield, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,12,17]]},"reference":[{"key":"bibr1-02692163241302454","doi-asserted-by":"publisher","DOI":"10.5772\/intechopen.103669"},{"key":"bibr2-02692163241302454","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtho.2023.01.095"},{"key":"bibr3-02692163241302454","doi-asserted-by":"publisher","DOI":"10.1177\/02692163211007379"},{"key":"bibr4-02692163241302454","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2354.2009.01162.x"},{"key":"bibr5-02692163241302454","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.20315"},{"key":"bibr6-02692163241302454","doi-asserted-by":"publisher","DOI":"10.1016\/j.hoc.2005.09.003"},{"issue":"3","key":"bibr7-02692163241302454","volume":"2","author":"MacLeod N","year":"2015","journal-title":"Rep Radiother Oncol"},{"key":"bibr8-02692163241302454","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejon.2016.09.007"},{"key":"bibr9-02692163241302454","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-023-03410-4"},{"issue":"4","key":"bibr10-02692163241302454","first-page":"491","volume":"1","author":"Robinson BM.","year":"2012","journal-title":"Ann Cardiothorac Surg"},{"key":"bibr11-02692163241302454","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2018.00205"},{"key":"bibr12-02692163241302454","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6604879"},{"key":"bibr13-02692163241302454","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdr602"},{"key":"bibr14-02692163241302454","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2003.03.059"},{"key":"bibr15-02692163241302454","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1000678"},{"key":"bibr16-02692163241302454","doi-asserted-by":"publisher","DOI":"10.1136\/thoraxjnl-2018-212380"},{"key":"bibr17-02692163241302454","doi-asserted-by":"publisher","DOI":"10.1111\/jan.15277"},{"key":"bibr18-02692163241302454","doi-asserted-by":"crossref","unstructured":"Davies JM, Sleeman KE, Leniz J, Wilson R, Higginson IJ, Verne J, Maddocks M, Murtagh FE. 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