{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T23:15:27Z","timestamp":1782170127636,"version":"3.54.5"},"reference-count":52,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T00:00:00Z","timestamp":1766707200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T00:00:00Z","timestamp":1766707200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100006041","name":"Innovate UK","doi-asserted-by":"publisher","award":["10,047,799"],"award-info":[{"award-number":["10,047,799"]}],"id":[{"id":"10.13039\/501100006041","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100018693","name":"HORIZON EUROPE","doi-asserted-by":"crossref","award":["101057043"],"award-info":[{"award-number":["101057043"]}],"id":[{"id":"10.13039\/100018693","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100023232","name":"National Institute for Health Research Applied Research Collaboration South London","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100023232","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000269","name":"Economic and Social Research Council","doi-asserted-by":"publisher","award":["ES\/Z50337X\/1"],"award-info":[{"award-number":["ES\/Z50337X\/1"]}],"id":[{"id":"10.13039\/501100000269","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Palliat Med"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Mobility loss is a common symptom in people with advanced cancer and is associated with reduced function and quality of life. While its physical consequences are well documented, less is known about how individuals and their families experience and adapt to these changes over time.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>To explore how individuals with advanced cancer and their caregivers experience and respond to mobility loss.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>A qualitative longitudinal study using Interpretative Phenomenological Analysis. Participants completed two semi-structured interviews, with follow-ups prompted by changes in mobility.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting\/participants:<\/jats:title>\n                    <jats:p>Twelve participants (10 people with advanced cancer, 2 caregivers) were recruited from hospital services, hospices, and cancer charities across England. Interviews were conducted 6\u201324\u2009weeks apart in person, online, or via telephone.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Four interrelated themes were identified: (i)\n                      <jats:italic toggle=\"yes\">Fractured embodiment: Loss of the mobile self<\/jats:italic>\n                      ; (ii)\n                      <jats:italic toggle=\"yes\">Mobility as a cornerstone: Disruption to the fabric of daily life<\/jats:italic>\n                      ; (iii)\n                      <jats:italic toggle=\"yes\">Resisting and reframing loss of mobility<\/jats:italic>\n                      ; and (iv)\n                      <jats:italic toggle=\"yes\">Mobility loss: The unseen symptom<\/jats:italic>\n                      . Mobility loss disrupted identity, agency, and participation, and led to reconfigured family roles. Coping with mobility change was dynamic and involved reframing expectations and negotiating autonomy. Participants often faced delayed or absent support, with unmet mobility needs frequently overlooked by clinicians.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Mobility loss in advanced cancer is not only a symptom of disease, but also a personal and relational disruption. Recognising it as a multidimensional experience underscores the need for holistic, anticipatory care that supports both physical functioning and the emotional realities of serious illness.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/02692163251400115","type":"journal-article","created":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T11:50:04Z","timestamp":1766749804000},"page":"206-216","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["The unseen symptom: A longitudinal qualitative interview study exploring mobility loss in people with advanced cancer"],"prefix":"10.1177","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-1462-5960","authenticated-orcid":false,"given":"Carmine","family":"Petrasso","sequence":"first","affiliation":[{"name":"Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, King\u2019s College London, England, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0516-0102","authenticated-orcid":false,"given":"Lisa Jane","family":"Brighton","sequence":"additional","affiliation":[{"name":"Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, King\u2019s College London, England, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0189-0952","authenticated-orcid":false,"given":"Matthew","family":"Maddocks","sequence":"additional","affiliation":[{"name":"Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, King\u2019s College London, England, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9478-8932","authenticated-orcid":false,"given":"Joanne","family":"Bayly","sequence":"additional","affiliation":[{"name":"Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, King\u2019s College London, England, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,12,26]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/onco.13751"},{"key":"e_1_3_3_3_2","article-title":"The association between having assistive devices and activities of daily living ability and health-related quality of life: an exploratory cross-sectional study among people with advanced cancer","volume":"28","author":"Funch A","year":"2019","unstructured":"Funch A, Kruse NB, la Cour K, et al. The association between having assistive devices and activities of daily living ability and health-related quality of life: an exploratory cross-sectional study among people with advanced cancer. Eur J Cancer Care 2019; 28: e13002.","journal-title":"Eur J Cancer Care"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-018-4437-1"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/geront\/gnq013"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejon.2014.06.005"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.19.00470"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1080\/09638288.2020.1820587"},{"key":"e_1_3_3_9_2","first-page":"569","article-title":"Non-pharmacological interventions targeting mobility among people with advanced cancer: a systematic review","volume":"32","author":"Petrasso C","year":"2024","unstructured":"Petrasso C, Bayly J, Arculeo S, et al. Non-pharmacological interventions targeting mobility among people with advanced cancer: a systematic review. Support Care Cancer 2024; 32: 569.","journal-title":"Support Care Cancer"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctrv.2017.10.006"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-024-03743-8"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.3390\/cancers14061368"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2019.07.005"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1136\/spcare-2024-004940"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1589\/jpts.37.12"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/jan.12215"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1097\/PHM.0000000000001622"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0169071"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2288-13-14"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1093\/intqhc\/mzm042"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1177\/1049732315617444"},{"key":"e_1_3_3_22_2","first-page":"51","volume-title":"Qualitative psychology: a practical guide to research methods","author":"Smith JA","year":"2003","unstructured":"Smith JA, Osborn M. Interpretative phenomenological analysis. In: Smith JA (ed.) Qualitative psychology: a practical guide to research methods. Sage Publications. Inc, 2003, pp.51\u201380."},{"key":"e_1_3_3_23_2","first-page":"204","article-title":"Ontology to outcome: a critical analysis of psychology research","volume":"15","author":"Grace JD","year":"2015","unstructured":"Grace JD, Priest H. Ontology to outcome: a critical analysis of psychology research. J Crit Psychol Couns Psychother 2015; 15: 204\u2013213.","journal-title":"J Crit Psychol Couns Psychother"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.radi.2019.11.092"},{"key":"e_1_3_3_25_2","first-page":"1","article-title":"A practical guide to reflexivity in qualitative research: AMEE Guide No. 149","volume":"45","author":"Olmos-Vega FM","year":"2022","unstructured":"Olmos-Vega FM, Stalmeijer RE, Varpio L, et al. A practical guide to reflexivity in qualitative research: AMEE Guide No. 149. Med Teach 2022; 45: 1\u201311.","journal-title":"Med Teach"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/0147-1767(85)90062-8"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1093\/acprof:oso\/9780199669653.001.0001"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1111\/1467-9566.ep11339939"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1186\/1472-684X-10-15"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1002\/pon.5453"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12877-022-02998-5"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.3390\/healthcare12101042"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1111\/1467-9566.ep10491512"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1089\/jpm.2013.0338"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-025-96861-3"},{"key":"e_1_3_3_36_2","volume-title":"The absent body","author":"Leder D","year":"1990","unstructured":"Leder D. The absent body. University of Chicago Press, 1990."},{"key":"e_1_3_3_37_2","doi-asserted-by":"publisher","DOI":"10.1017\/S1478951515000620"},{"key":"e_1_3_3_38_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmjspcare-2014-000744"},{"key":"e_1_3_3_39_2","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2019.00783"},{"key":"e_1_3_3_40_2","doi-asserted-by":"publisher","DOI":"10.1093\/oncolo\/oyad253"},{"key":"e_1_3_3_41_2","volume-title":"Stress, appraisal, and coping","author":"Lazarus RS","year":"1984","unstructured":"Lazarus RS, Folkman S. Stress, appraisal, and coping. Springer, 1984."},{"key":"e_1_3_3_42_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-008-0461-x"},{"key":"e_1_3_3_43_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jgo.2015.01.004"},{"key":"e_1_3_3_44_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2020.07.030"},{"key":"e_1_3_3_45_2","doi-asserted-by":"publisher","DOI":"10.3390\/healthcare10061005"},{"key":"e_1_3_3_46_2","doi-asserted-by":"publisher","DOI":"10.5965\/19847246242023e0116"},{"key":"e_1_3_3_47_2","first-page":"57","volume-title":"The rejected body: Feminist philosophical reflections on disability","author":"Wendell S","year":"1996","unstructured":"Wendell S (ed.). The social construction of disability. In: The rejected body: Feminist philosophical reflections on disability. Routledge, 1996, pp.57\u201371."},{"key":"e_1_3_3_48_2","article-title":"Integrated short-term palliative rehabilitation to improve quality of life and equitable care access in incurable cancer (INSPIRE): a multinational European research project","volume":"17","author":"Bayly J","year":"2023","unstructured":"Bayly J, Ahmedzai HH, Blandini MG, et al. Integrated short-term palliative rehabilitation to improve quality of life and equitable care access in incurable cancer (INSPIRE): a multinational European research project. PalliatCare 2023; 17: 26323524231179979.","journal-title":"PalliatCare"},{"key":"e_1_3_3_49_2","doi-asserted-by":"publisher","DOI":"10.1177\/02692163211015574"},{"key":"e_1_3_3_50_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2022-063938"},{"key":"e_1_3_3_51_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2025.02.383"},{"key":"e_1_3_3_52_2","volume-title":"The World Health Organization Quality of Life (WHOQOL)","author":"World Health Organisation","year":"2012","unstructured":"World Health Organisation. The World Health Organization Quality of Life (WHOQOL). Geneva: World Health Organisation, 2012."},{"key":"e_1_3_3_53_2","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21639"}],"container-title":["Palliative Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02692163251400115","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/02692163251400115","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02692163251400115","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T06:45:13Z","timestamp":1778913913000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/02692163251400115"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,26]]},"references-count":52,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["10.1177\/02692163251400115"],"URL":"https:\/\/doi.org\/10.1177\/02692163251400115","relation":{},"ISSN":["0269-2163","1477-030X"],"issn-type":[{"value":"0269-2163","type":"print"},{"value":"1477-030X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,26]]}}}