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However, its effectiveness and implementation requirements in palliative care remain unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>This study evaluates the effectiveness of and implementation requirements for telehealth in palliative care patients with advanced cancer.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>This was designed as a systematic review and meta-analysis with narrative synthesis (registered; CRD42024581786). The effects on patients\u2019 quality of life, symptom burden, and depression were analyzed using a random-effects meta-analysis of randomized controlled trials. A narrative synthesis was conducted for all included studies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Data sources:<\/jats:title>\n                    <jats:p>MEDLINE, Embase, and Cochrane Library databases were searched in September 2025. Eligible studies comprised controlled trials, observational studies, and qualitative studies involving adults with advanced cancer who received telehealth in palliative care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Of the 4232 records screened, 42 met the inclusion criteria, and six were eligible for meta-analysis. Telehealth interventions primarily involved videoconferencing, telephone, or text-based communication. Telehealth in palliative care demonstrated significant improvement in quality of life (standardized mean difference: 0.81; 95% CI: 0.09-1.53) and reduction in symptom burden (standardized mean difference: \u22121.44; 95% CI: \u22122.24 to \u22120.65) but had no significant effects on depression. Implementation requirements included trained multiprofessional teams, accessible digital infrastructure, sustainable reimbursement mechanisms, and standardized outcome measurements.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Telehealth in palliative care may help improve quality of life and alleviate symptom burden among patients with advanced cancer. Future research should identify optimal delivery models and examine equity-related barriers to support wider implementation and policy development.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/02692163251403395","type":"journal-article","created":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T12:44:51Z","timestamp":1767098691000},"page":"588-607","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Effectiveness of and implementation requirements for telehealth in palliative care patients with advanced cancer: A systematic review and meta-analysis"],"prefix":"10.1177","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7864-9289","authenticated-orcid":false,"given":"Arisa","family":"Kawashima","sequence":"first","affiliation":[{"name":"Division of Integrated Health Sciences, Nagoya University Graduate School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9165-5501","authenticated-orcid":false,"given":"Taiji","family":"Noguchi","sequence":"additional","affiliation":[{"name":"Department of Community Health and Preventive Medicine, Hamamatsu University School of Medicine, Shizuoka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3522-1845","authenticated-orcid":false,"given":"Taiki","family":"Furukawa","sequence":"additional","affiliation":[{"name":"Medical IT Center, Nagoya University Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2540-148X","authenticated-orcid":false,"given":"Akiko","family":"Unesoko","sequence":"additional","affiliation":[{"name":"Department of Nursing, Konan Kosei Hospital, Aichi, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shintaro","family":"Togashi","sequence":"additional","affiliation":[{"name":"National Institute of Public Health, Wako-shi, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuki","family":"Sato","sequence":"additional","affiliation":[{"name":"Division of Integrated Health Sciences, Nagoya University Graduate School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,12,30]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2024.47649"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1200\/JOP.18.00234"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2024.02.572"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2024.13964"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.2196\/16218"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2015.63.0830"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1089\/pmr.2020.0075"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.2196\/54244"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmjspcare-2015-001016"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1089\/jpm.2020.0117"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1177\/1357633X211048952"},{"issue":"8","key":"e_1_3_3_13_2","first-page":"451","article-title":"Telehealth palliative care interventions for patients with advanced cancer: a scoping review","volume":"31","author":"Mathews JJ","year":"2023","unstructured":"Mathews JJ, Chow R, Wennberg E, et al. 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