{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T01:29:22Z","timestamp":1777858162681,"version":"3.51.4"},"reference-count":24,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2003,6,1]],"date-time":"2003-06-01T00:00:00Z","timestamp":1054425600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Psychopharmacol"],"published-print":{"date-parts":[[2003,6]]},"abstract":"<jats:p>The effects of gabapentin, 400 mg and 800 mg, on anxiety induced by simulated public speaking (SPS) were investigated. Thirty-two normal male volunteers (aged 17-30 years) had their anxiety and mood evaluated by self-scales [Visual Analogue Mood Scale (VAMS) and Profile of Mood State (POMS)] during the SPS procedure. Physiological measures (heart rate and blood pressure) were taken. Treatment with gabapentin at 800 mg attenuated the anxiety of subjects that had a decrease on the VAMS item calm-excite. In addition, volunteers that received gabapentin at 400 mg and 800 mg showed a decrease in the hostility score in POMS. Our results suggest, in agreement with other studies, an anxiolytic potential to gabapentin.<\/jats:p>","DOI":"10.1177\/0269881103017002006","type":"journal-article","created":{"date-parts":[[2003,7,3]],"date-time":"2003-07-03T17:45:03Z","timestamp":1057254303000},"page":"184-188","source":"Crossref","is-referenced-by-count":33,"title":["Effects of Gabapentin on Anxiety Induced by Simulated Public Speaking"],"prefix":"10.1177","volume":"17","author":[{"given":"Joao","family":"Quevedo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatiana","family":"Barichello","sequence":"additional","affiliation":[{"name":"Laboratorio de Neurotoxicologia, Universidade do Extremo Sul Catarinense,                        Criciuma, Brasil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivan","family":"Izquierdo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monica R. 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