{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T13:12:01Z","timestamp":1791119521438,"version":"4.1.0"},"reference-count":27,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2004,3,1]],"date-time":"2004-03-01T00:00:00Z","timestamp":1078099200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Psychopharmacol"],"published-print":{"date-parts":[[2004,3]]},"abstract":"<jats:p>We report on three males with prominent apathy as part of the symptom complex of depression or organic brain disease. Significant clinical responses were observed following treatment with bupropion, an antidepressant with dopamine (DA) reuptake activity. We present clinical evidence in support of the hypothesis that remission in these patients occurred as a consequence of bupropion-induced increases in central DA neurotransmission.<\/jats:p>","DOI":"10.1177\/0269881104043284","type":"journal-article","created":{"date-parts":[[2004,4,21]],"date-time":"2004-04-21T21:27:18Z","timestamp":1082582838000},"page":"133-135","source":"Crossref","is-referenced-by-count":58,"title":["Bupropion in the management of apathy"],"prefix":"10.1177","volume":"18","author":[{"given":"C.","family":"Corcoran","sequence":"first","affiliation":[{"name":"Department of Psychiatry, Beaumont Hospital, Dublin, Ireland."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. L.","family":"Wong","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Beaumont Hospital, Dublin, Ireland."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"O\u2019Keane","sequence":"additional","affiliation":[{"name":"Department of Perinatal Psychiatry, Institute of Psychiatry,                        King\u2019s College London, De Crespigny Park, London, UK."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2004,3,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1080\/026990599121458"},{"key":"atypb2","unstructured":"Ascher J A, Cole J O, Colin J N, Feighner J P, Ferris R M, Fibiger H C, Golden R N, Martin P, Potter W Z, Richelson E, Susler F (1995) Bupropion: a review of its mechanism of antidepressant activity . J Clin Psychiatry 56: 395\u2013401"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.54.8.718"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/117.4.859"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1993.00540080076020"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.44.12.2308"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1016\/S0028-3932(02)00108-2"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/118.1.279"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1007\/s002130000665"},{"key":"atypb10","doi-asserted-by":"crossref","unstructured":"Hughes J R, Stead L F, Lancaster T (2003) Antidepressants for smoking cessation . Cochrane Database Syst Rev 2: CD000031","DOI":"10.1002\/14651858.CD000031"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1007\/s11940-002-0005-5"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.1080\/026990598122908"},{"key":"atypb13","doi-asserted-by":"publisher","DOI":"10.1080\/026990597123430"},{"key":"atypb14","doi-asserted-by":"publisher","DOI":"10.1176\/jnp.10.3.314"},{"key":"atypb15","doi-asserted-by":"crossref","unstructured":"Lindvall O, Stenevi U (1978) Dopamine and noradrenaline neurons projecting to the septal area in the rat . Cell Tissue Res 190: 383\u2013407","DOI":"10.1007\/BF00219554"},{"key":"atypb16","doi-asserted-by":"publisher","DOI":"10.1176\/jnp.7.1.23"},{"key":"atypb17","doi-asserted-by":"publisher","DOI":"10.1016\/0165-0327(93)90040-Q"},{"key":"atypb18","doi-asserted-by":"publisher","DOI":"10.1016\/0165-1781(91)90040-V"},{"key":"atypb19","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.46.1.130"},{"key":"atypb20","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-002-1166-3"},{"key":"atypb21","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.24.11.1625"},{"key":"atypb22","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3999(02)00428-2"},{"key":"atypb23","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.157.1.75"},{"key":"atypb24","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-4328(97)00153-8"},{"key":"atypb25","doi-asserted-by":"publisher","DOI":"10.1002\/syn.10084"},{"key":"atypb26","unstructured":"Yudofsky S C, Hales R E (2002) Textbook of neuropsychiatry and clinical neurosciences, 4th edn, p. 746. American Psychiatric Press, Inc., Washington, DC"},{"key":"atypb27","doi-asserted-by":"publisher","DOI":"10.1176\/jnp.14.3.296"}],"container-title":["Journal of Psychopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0269881104043284","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0269881104043284","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:08:55Z","timestamp":1777507735000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0269881104043284"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,3]]},"references-count":27,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2004,3]]}},"alternative-id":["10.1177\/0269881104043284"],"URL":"https:\/\/doi.org\/10.1177\/0269881104043284","relation":{},"ISSN":["0269-8811","1461-7285"],"issn-type":[{"value":"0269-8811","type":"print"},{"value":"1461-7285","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,3]]}}}