{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T18:08:25Z","timestamp":1792001305533,"version":"4.4.0"},"reference-count":18,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2006,5,1]],"date-time":"2006-05-01T00:00:00Z","timestamp":1146441600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Psychopharmacol"],"published-print":{"date-parts":[[2006,5]]},"abstract":"<jats:p>In recent years working memory de.cits have been reported in users of MDMA (3,4-methylenedioxymethamphetamine, ecstasy). The current study aimed to assess the impact of MDMA use on three separate central executive processes (set shifting, inhibition and memory updating) and also on \u00ebprefrontal\u00ed mediated social and emotional judgement processes. Fifteen polydrug ecstasy users and 15 polydrug non-ecstasy user controls completed a general drug use questionnaire, the Brixton Spatial Anticipation task (set shifting), Backward Digit Span procedure (memory updating), Inhibition of Return (inhibition), an emotional intelligence scale, the Tromso Social Intelligence Scale and the Dysexecutive Questionnaire (DEX). Compared with MDMA-free polydrug controls, MDMA polydrug users showed impairments in set shifting and memory updating, and also in social and emotional judgement processes. The latter two de.cits remained signi.cant after controlling for other drug use. These data lend further support to the proposal that cognitive processes mediated by the prefrontal cortex may be impaired by recreational ecstasy use.<\/jats:p>","DOI":"10.1177\/0269881106063269","type":"journal-article","created":{"date-parts":[[2006,3,30]],"date-time":"2006-03-30T08:05:45Z","timestamp":1143705945000},"page":"385-388","source":"Crossref","is-referenced-by-count":69,"title":["MDMA polydrug users show processspecific central executive impairments                 coupled with impaired social and emotional judgement processes"],"prefix":"10.1177","volume":"20","author":[{"given":"J. L.","family":"Reay","sequence":"first","affiliation":[{"name":"Human Cognitive Neuroscience Unit, Division of Psychology, Northumbria                         University, Newcastle upon Tyne, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Hamilton","sequence":"additional","affiliation":[{"name":"Cognition and Communication Research Centre, Division of Psychology,                         Northumbria University, Newcastle upon Tyne, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. O.","family":"Kennedy","sequence":"additional","affiliation":[{"name":"Human Cognitive Neuroscience Unit, Division of Psychology, Northumbria                         University, Newcastle upon Tyne, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. B.","family":"Scholey","sequence":"additional","affiliation":[{"name":"Human Cognitive Neuroscience Unit, Division of Psychology, Northumbria                         University, Newcastle upon Tyne, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2006,5,1]]},"reference":[{"key":"atypb1","volume-title":"The Hayling and Brixton tests","author":"Burgess P W","year":"1997"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1348\/0007126042369785"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1016\/S1364-6613(99)01388-1"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-004-1832-8"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1006\/cogp.1999.0734"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1016\/j.coph.2004.08.007"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1002\/hup.351"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1016\/S1041-6080(99)80131-9"},{"key":"atypb9","volume-title":"The Psychology of Attention","author":"Posner J","year":"1984"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1016\/j.addbeh.2004.02.022"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1016\/S0191-8869(98)00001-4"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.1111\/1467-9450.00242"},{"key":"atypb13","doi-asserted-by":"publisher","DOI":"10.1016\/j.addbeh.2004.04.015"},{"key":"atypb14","doi-asserted-by":"publisher","DOI":"10.1348\/000712600161772"},{"key":"atypb15","doi-asserted-by":"publisher","DOI":"10.1002\/hup.586"},{"key":"atypb16","doi-asserted-by":"publisher","DOI":"10.1002\/hup.670"},{"key":"atypb17","volume-title":"Behavioural Assessment of the Dysexecutive Syndrome (BADS)","author":"Wilson B A","year":"1996"},{"key":"atypb18","first-page":"1292","volume":"7","author":"Zakzanis K K","year":"2001","journal-title":"Med Sci Monit"}],"container-title":["Journal of Psychopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0269881106063269","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0269881106063269","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:09:51Z","timestamp":1777507791000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0269881106063269"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,5]]},"references-count":18,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2006,5]]}},"alternative-id":["10.1177\/0269881106063269"],"URL":"https:\/\/doi.org\/10.1177\/0269881106063269","relation":{},"ISSN":["0269-8811","1461-7285"],"issn-type":[{"value":"0269-8811","type":"print"},{"value":"1461-7285","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,5]]}}}