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Using a new data set consisting of 135,095 randomly selected United States adults, including 19,299 psychedelic users, we examine the associations between psychedelic use and mental health. After adjusting for sociodemographics, other drug use and childhood depression, we found no significant associations between lifetime use of psychedelics and increased likelihood of past year serious psychological distress, mental health treatment, suicidal thoughts, suicidal plans and suicide attempt, depression and anxiety. We failed to find evidence that psychedelic use is an independent risk factor for mental health problems. Psychedelics are not known to harm the brain or other body organs or to cause addiction or compulsive use; serious adverse events involving psychedelics are extremely rare. Overall, it is difficult to see how prohibition of psychedelics can be justified as a public health measure.<\/jats:p>","DOI":"10.1177\/0269881114568039","type":"journal-article","created":{"date-parts":[[2015,3,5]],"date-time":"2015-03-05T21:04:16Z","timestamp":1425589456000},"page":"270-279","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":254,"title":["Psychedelics not linked to mental health problems or suicidal behavior: A population study"],"prefix":"10.1177","volume":"29","author":[{"given":"P\u00e5l-\u00d8rjan","family":"Johansen","sequence":"first","affiliation":[{"name":"EmmaSofia, Oslo, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teri Suzanne","family":"Krebs","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Norwegian University of Science and Technology, Trondheim, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2015,3,5]]},"reference":[{"key":"bibr1-0269881114568039","volume-title":"Diagnostic and Statistical Manual of Mental Health Disorders","author":"American Psychiatric Association","year":"1994","edition":"4"},{"key":"bibr2-0269881114568039","volume-title":"The Moment: Wild, Poignant, Life-Changing Stories from 125 Writers and Artists Famous & Obscure","author":"Baum D","year":"2012"},{"key":"bibr3-0269881114568039","doi-asserted-by":"publisher","DOI":"10.1177\/2045125314527985"},{"key":"bibr4-0269881114568039","unstructured":"BMA (2012) Risk: What\u2019s your perspective? 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