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A tryptophan depletion study in panic disorder patients recovered on paroxetine\u201d by Bell and colleagues \u2013 reprinted in this issue of the Journal \u2013 reports on a study undertaken in the halcyon days of David Nutt\u2019s Psychopharmacology Unit at the University of Bristol, England. In this invited commentary authors of the original work discuss the impact of this paper on the field of acute tryptophan depletion research (especially in the field of clinical anxiety disorders) and the development of disorder-specific anxiogenic provocations over the past decade.<\/jats:p>","DOI":"10.1177\/0269881116655321","type":"journal-article","created":{"date-parts":[[2016,6,22]],"date-time":"2016-06-22T15:33:49Z","timestamp":1466609629000},"page":"1137-1140","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Don\u2019t panic. 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