{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T14:06:32Z","timestamp":1792677992558,"version":"4.5.0"},"reference-count":624,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2020,11,11]],"date-time":"2020-11-11T00:00:00Z","timestamp":1605052800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Psychopharmacol"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:p>This paper introduces a new construct, the \u2018pivotal mental state\u2019, which is defined as a hyper-plastic state aiding rapid and deep learning that can mediate psychological transformation. We believe this new construct bears relevance to a broad range of psychological and psychiatric phenomena. We argue that pivotal mental states serve an important evolutionary function, that is, to aid psychological transformation when actual or perceived environmental pressures demand this. We cite evidence that chronic stress and neurotic traits are primers for a pivotal mental state, whereas acute stress can be a trigger. Inspired by research with serotonin 2A receptor agonist psychedelics, we highlight how activity at this particular receptor can robustly and reliably induce pivotal mental states, but we argue that the capacity for pivotal mental states is an inherent property of the human brain itself. Moreover, we hypothesize that serotonergic psychedelics hijack a system that has evolved to mediate rapid and deep learning when its need is sensed. We cite a breadth of evidences linking stress via a variety of inducers, with an upregulated serotonin 2A receptor system (e.g. upregulated availability of and\/or binding to the receptor) and acute stress with 5-HT release, which we argue can activate this primed system to induce a pivotal mental state. The pivotal mental state model is multi-level, linking a specific molecular gateway (increased serotonin 2A receptor signaling) with the inception of a hyper-plastic brain and mind state, enhanced rate of associative learning and the potential mediation of a psychological transformation.<\/jats:p>","DOI":"10.1177\/0269881120959637","type":"journal-article","created":{"date-parts":[[2020,11,11]],"date-time":"2020-11-11T05:18:38Z","timestamp":1605071918000},"page":"319-352","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":133,"title":["Pivotal mental states"],"prefix":"10.1177","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7253-4664","authenticated-orcid":false,"given":"Ari","family":"Brouwer","sequence":"first","affiliation":[{"name":"Centre for Psychedelic Research, Imperial College London, London, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6062-7150","authenticated-orcid":false,"given":"Robin Lester","family":"Carhart-Harris","sequence":"additional","affiliation":[{"name":"Centre for Psychedelic Research, Imperial College London, London, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,11,11]]},"reference":[{"key":"bibr1-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00575.2014"},{"key":"bibr2-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/0028-3908(95)00136-0"},{"key":"bibr3-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2011.04.007"},{"key":"bibr4-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/S0028-3908(97)00048-8"},{"key":"bibr5-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-0173(99)00046-6"},{"key":"bibr6-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1037\/tra0000471"},{"key":"bibr7-0269881120959637","doi-asserted-by":"crossref","unstructured":"Alamia A, Timmermann C, VanRullen R, et al. (2020) DMT alters cortical travelling waves. Available at: https:\/\/doi.org\/10.1101\/2020.05.06.080937","DOI":"10.1101\/2020.05.06.080937"},{"key":"bibr8-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2006.06.069"},{"key":"bibr9-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1097\/FBP.0b013e3282effc0d"},{"key":"bibr10-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1159\/000125347"},{"key":"bibr11-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1038\/nn1399"},{"key":"bibr12-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-8993(98)00368-0"},{"key":"bibr13-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1080\/08039488.2016.1276624"},{"key":"bibr14-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1037\/emo0000442"},{"key":"bibr15-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2011.01.015"},{"key":"bibr16-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2005.04.026"},{"key":"bibr17-0269881120959637","first-page":"131","volume":"33","author":"Anisman H","year":"2008","journal-title":"J Psychiatr Neurosci"},{"key":"bibr18-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1007\/s12031-010-9449-3"},{"key":"bibr19-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/0306-4522(91)90128-B"},{"key":"bibr20-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2017-016025"},{"key":"bibr21-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2018.06.012"},{"key":"bibr22-0269881120959637","first-page":"163","volume":"44","author":"Audenaert K","year":"2003","journal-title":"J Nucl Med"},{"key":"bibr23-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1177\/0146167210367491"},{"key":"bibr24-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/S0361-9230(01)00614-1"},{"key":"bibr25-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.pscychresns.2013.12.005"},{"key":"bibr26-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2006.07.018"},{"key":"bibr27-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1038\/sj.npp.1300430"},{"key":"bibr28-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1111\/bjp.12230"},{"key":"bibr29-0269881120959637","first-page":"27","volume":"6","author":"Ballard C","year":"2019","journal-title":"J Prev Alzheimers Dis"},{"key":"bibr30-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1177\/0269881116678781"},{"key":"bibr31-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-59282-y"},{"key":"bibr32-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1007\/7854_2017_474"},{"key":"bibr33-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.paid.2017.06.004"},{"key":"bibr34-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1177\/0956797616668510"},{"key":"bibr35-0269881120959637","doi-asserted-by":"publisher","DOI":"10.4081\/ni.2017.7043"},{"key":"bibr36-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2009.01.038"},{"key":"bibr37-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2004.11.002"},{"key":"bibr38-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2830-16.2016"},{"key":"bibr39-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1177\/0022167817706884"},{"key":"bibr40-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1037\/a0017376"},{"key":"bibr41-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3245-10.2010"},{"key":"bibr42-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1017\/S1461145712000168"},{"key":"bibr43-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2011.08.005"},{"key":"bibr44-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1001\/archneurpsyc.1956.02330240050004"},{"key":"bibr45-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/S0306-4522(97)00282-0"},{"key":"bibr46-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.2006.163.9.1580"},{"key":"bibr47-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-183X.2006.00280.x"},{"key":"bibr48-0269881120959637","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1096\/fasebj.2019.33.1_supplement.503.12","volume":"33","author":"Billac G","year":"2019","journal-title":"FASEB J"},{"key":"bibr49-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1038\/sj.npp.1300206"},{"key":"bibr50-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/S0306-4522(02)00810-2"},{"key":"bibr51-0269881120959637","volume":"95","author":"Bloche MG","year":"2016","journal-title":"Tex L Rev"},{"key":"bibr52-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1177\/0269881114565144"},{"key":"bibr53-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.pnpbp.2015.03.002"},{"key":"bibr54-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1002\/jclp.21965"},{"key":"bibr55-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1038\/sj.npp.1301584"},{"key":"bibr56-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-199801000-00015"},{"key":"bibr57-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1966.01730150016003"},{"key":"bibr58-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1080\/15299732.2014.970265"},{"key":"bibr59-0269881120959637","doi-asserted-by":"publisher","DOI":"10.4324\/9781315639550"},{"key":"bibr60-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.191.51.s38"},{"key":"bibr61-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-9384(97)00482-4"},{"key":"bibr62-0269881120959637","first-page":"31","volume":"51","author":"Brown GL","year":"1990","journal-title":"J Clin Psychiat"},{"key":"bibr63-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1089\/acm.2005.11.711"},{"key":"bibr64-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/133.6.696"},{"key":"bibr65-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-079X.1992.tb00020.x"},{"key":"bibr66-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00213.2015"},{"key":"bibr67-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/7.3.516"},{"key":"bibr68-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2003.08.004"},{"key":"bibr69-0269881120959637","first-page":"190","volume":"6","author":"Butelman ER","year":"2015","journal-title":"Front Pharmacol"},{"key":"bibr70-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1002\/jclp.20006"},{"key":"bibr71-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-006-0635-5"},{"key":"bibr72-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/0196-9781(89)90096-X"},{"key":"bibr73-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1021\/acschemneuro.8b00134"},{"key":"bibr74-0269881120959637","volume-title":"The Hero with a Thousand Faces","author":"Campbell J","year":"2008"},{"key":"bibr75-0269881120959637","volume-title":"The Incorruptible Flesh: Bodily Mutation and Mortification in Religion and Folklore","author":"Camporesi P","year":"1988"},{"key":"bibr76-0269881120959637","first-page":"239","volume":"15","author":"Cangas AJ","year":"2008","journal-title":"Philo Psychia Psychol"},{"key":"bibr77-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.ienj.2011.05.005"},{"key":"bibr78-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1177\/0269881116662634"},{"key":"bibr79-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2016.08.107"},{"key":"bibr80-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbu016"},{"key":"bibr81-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1080\/15294145.2007.10773557"},{"key":"bibr82-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1002\/wps.20555"},{"key":"bibr83-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2018.03.010"},{"key":"bibr84-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1097\/YCO.0000000000000467"},{"key":"bibr85-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-017-4771-x"},{"key":"bibr86-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/S2215-0366(16)30065-7"},{"key":"bibr87-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1177\/0269881113494107"},{"key":"bibr88-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-017-4701-y"},{"key":"bibr89-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1119598109"},{"key":"bibr90-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awq010"},{"key":"bibr91-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1124\/pr.118.017160"},{"key":"bibr92-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1038\/npp.2017.84"},{"key":"bibr93-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291715002901"},{"key":"bibr94-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-014-3714-z"},{"key":"bibr95-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbs117"},{"key":"bibr96-0269881120959637","doi-asserted-by":"publisher","DOI":"10.3389\/fnhum.2014.00020"},{"key":"bibr97-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1518377113"},{"key":"bibr98-0269881120959637","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2014.00255"},{"key":"bibr99-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1177\/0269881117725915"},{"key":"bibr100-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-13282-7"},{"key":"bibr101-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1177\/0269881118754710"},{"key":"bibr102-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1017\/S1461145713001405"},{"key":"bibr103-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1159\/000464106"},{"key":"bibr104-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/9064046"},{"key":"bibr105-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1007\/s00221-013-3579-0"},{"key":"bibr106-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3223(03)00236-1"},{"key":"bibr107-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2015.09.006"},{"key":"bibr108-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen.2016.11.015"},{"key":"bibr109-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/0028-3908(94)90075-2"},{"key":"bibr110-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/0091-3057(94)00297-V"},{"key":"bibr111-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1007\/BF00215473"},{"key":"bibr112-0269881120959637","doi-asserted-by":"publisher","DOI":"10.3390\/genes8010014"},{"key":"bibr113-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1017\/S1461145714000455"},{"key":"bibr114-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1017\/S0140525X12000477"},{"key":"bibr115-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/0005-7967(86)90011-2"},{"key":"bibr116-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2014.11.016"},{"key":"bibr117-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcbs.2020.01.005"},{"key":"bibr118-0269881120959637","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.06346"},{"key":"bibr119-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbw006"},{"key":"bibr120-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.physbeh.2016.11.017"},{"key":"bibr121-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291710000802"},{"key":"bibr122-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1177\/0269881116650087"},{"key":"bibr123-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbm028"},{"key":"bibr124-0269881120959637","doi-asserted-by":"publisher","DOI":"10.2174\/1570159X15666170911121027"},{"key":"bibr125-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-70474-6_14"},{"key":"bibr126-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbp020"},{"key":"bibr127-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0213456"},{"key":"bibr128-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1177\/136346159803500401"},{"key":"bibr129-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1111\/jcmm.13310"},{"key":"bibr130-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)62106-6"},{"key":"bibr131-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.euroneuro.2019.05.007"},{"key":"bibr132-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2016.01.053"},{"key":"bibr133-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcbs.2019.11.004"},{"key":"bibr134-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcbs.2019.11.004"},{"key":"bibr135-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2016.03.017"},{"key":"bibr136-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.pnpbp.2005.08.005"},{"key":"bibr137-0269881120959637","first-page":"123","volume":"2","author":"De Paulis T","year":"2001","journal-title":"Curr Opin Invest Dr"},{"key":"bibr138-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpr.2012.09.007"},{"key":"bibr139-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1177\/026988119100500414"},{"key":"bibr140-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-45812-w"},{"key":"bibr141-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1007\/s11089-013-0584-y"},{"key":"bibr142-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2014.08.037"},{"key":"bibr143-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2013.12.002"},{"key":"bibr144-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1093\/acprof:oso\/9780195137507.001.0001"},{"key":"bibr145-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1038\/nrn3027"},{"key":"bibr146-0269881120959637","volume-title":"The Brain That Changes Itself: Stories of Personal Triumph from the Frontiers of Brain Science","author":"Doidge N","year":"2007"},{"key":"bibr147-0269881120959637","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2018.01341"},{"key":"bibr148-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1038\/npp.2016.82"},{"key":"bibr149-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-011-2434-x"},{"key":"bibr150-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.socscimed.2016.05.033"},{"key":"bibr151-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1093\/jaarel\/LXIII.3.539"},{"key":"bibr152-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2004.10.004"},{"key":"bibr153-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1097\/00005053-195812000-00006"},{"key":"bibr154-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-psych-122216-011732"},{"key":"bibr155-0269881120959637","doi-asserted-by":"publisher","DOI":"10.5665\/sleep.2230"},{"key":"bibr156-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1186\/1471-244X-13-50"},{"key":"bibr157-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1126\/science.847460"},{"key":"bibr158-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-9280.2008.02056.x"},{"key":"bibr159-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1001\/archgenpsychiatry.2011.56"},{"key":"bibr160-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1177\/0957154X17692197"},{"key":"bibr161-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1038\/sj.npp.1301656"},{"key":"bibr162-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1111\/acps.12904"},{"key":"bibr163-0269881120959637","volume-title":"Asceticism in Early Taoist Religion","author":"Eskildsen S","year":"1998"},{"key":"bibr164-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1109\/HRI.2013.6483531"},{"key":"bibr165-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/S0893-133X(00)00211-6"},{"key":"bibr166-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1821332116"},{"key":"bibr167-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1163\/9789004225343_012"},{"key":"bibr168-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2014.07.024"},{"key":"bibr169-0269881120959637","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2019.00412"},{"key":"bibr170-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/1.1.1"},{"key":"bibr171-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/S0306-4530(97)00052-8"},{"key":"bibr172-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.pnpbp.2012.03.015"},{"key":"bibr173-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-012-2795-9"},{"key":"bibr174-0269881120959637","doi-asserted-by":"publisher","DOI":"10.3389\/neuro.08.003.2007"},{"key":"bibr175-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/9.1.73"},{"key":"bibr176-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1080\/09540261.2018.1481827"},{"key":"bibr177-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2019.116790"},{"key":"bibr178-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-49987-0"},{"key":"bibr179-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2012.12.018"},{"key":"bibr180-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2014.12.002"},{"key":"bibr181-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1177\/0269881117714049"},{"key":"bibr182-0269881120959637","volume-title":"The Transforming Power of Affect: A Model for Accelerated Change","author":"Fosha D","year":"2000"},{"key":"bibr183-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sby125"},{"key":"bibr184-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3223(02)01378-1"},{"key":"bibr185-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-8993(02)03548-5"},{"key":"bibr186-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291714000592"},{"key":"bibr187-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1080\/01973531003738387"},{"key":"bibr188-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1971.03190110067020"},{"key":"bibr189-0269881120959637","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2018.00579"},{"key":"bibr190-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2007.07.009"},{"key":"bibr191-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5381.1984.tb16495.x"},{"key":"bibr192-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3940(02)00029-0"},{"key":"bibr193-0269881120959637","first-page":"402","volume":"57","author":"Galynker I","year":"1996","journal-title":"J Clin Psychiat"},{"key":"bibr194-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1517\/13543784.2016.1121995"},{"key":"bibr195-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2017.01.021"},{"key":"bibr196-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.brat.2005.07.008"},{"key":"bibr197-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2005.07.042"},{"key":"bibr198-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1002\/j.1556-6678.2011.tb00096.x"},{"key":"bibr199-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1037\/rel0000025"},{"key":"bibr200-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1177\/0269881114555249"},{"key":"bibr201-0269881120959637","volume-title":"The Third Man Factor","author":"Geiger J","year":"2009"},{"key":"bibr202-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1097\/MED.0b013e32835bc703"},{"key":"bibr203-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-3057(02)00844-4"},{"key":"bibr204-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/S0893-133X(99)00123-2"},{"key":"bibr205-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.tips.2008.06.006"},{"key":"bibr206-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1207\/s15327582ijpr1601_5"},{"key":"bibr207-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/0024-3205(84)90436-3"},{"key":"bibr208-0269881120959637","first-page":"330","volume":"208","author":"Gimpl MP","year":"1979","journal-title":"J Pharmacol Exp Ther"},{"key":"bibr209-0269881120959637","unstructured":"Girn M, Roseman L, Bernhardt B, et al. (2020) LSD flattens the functional hierarchy of the human brain."},{"key":"bibr210-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1007\/s10781-012-9164-1"},{"key":"bibr211-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2019.01.028"},{"key":"bibr212-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.tins.2008.12.005"},{"key":"bibr213-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0447.2002._10424.x"},{"key":"bibr214-0269881120959637","volume-title":"The Scientist in the Crib: Minds, Brains, and How Children Learn","author":"Gopnik A","year":"1999"},{"key":"bibr215-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-70474-6_15"},{"key":"bibr216-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-3057(98)00106-3"},{"key":"bibr217-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1055\/s-2005-916185"},{"key":"bibr218-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2012.08.034"},{"key":"bibr219-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0214377"},{"key":"bibr220-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1177\/0269881116675513"},{"key":"bibr221-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-011-2358-5"},{"key":"bibr222-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1177\/0269881117731279"},{"key":"bibr223-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1177\/0269881108094300"},{"key":"bibr224-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-006-0457-5"},{"key":"bibr225-0269881120959637","volume-title":"Spiritual Emergency: When Personal Transformation Becomes a Crisis","author":"Grof S","year":"1989"},{"key":"bibr226-0269881120959637","doi-asserted-by":"crossref","DOI":"10.1515\/9781438433950","volume-title":"Holotropic Breathwork","author":"Grof S","year":"2010"},{"key":"bibr227-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpr.2011.04.003"},{"key":"bibr228-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2008.07.011"},{"key":"bibr229-0269881120959637","volume-title":"Faces in the Clouds: A New Theory of Religion","author":"Guthrie SE","year":"1995"},{"key":"bibr230-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1038\/npp.2017.167"},{"key":"bibr231-0269881120959637","first-page":"1061","volume":"6","author":"Haider S","year":"2000","journal-title":"Med Sci Monitor"},{"key":"bibr232-0269881120959637","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2018.00897"},{"key":"bibr233-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2010.11.012"},{"key":"bibr234-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1086\/696041"},{"key":"bibr235-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2013.12111395"},{"key":"bibr236-0269881120959637","volume-title":"The Spiritual Nature of Man: A Study of Contemporary Religious Experiences","author":"Hardy A","year":"1979"},{"key":"bibr237-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1177\/0269881116677852"},{"key":"bibr238-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-8993(03)03033-6"},{"key":"bibr239-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/0166-4328(96)00068-X"},{"key":"bibr240-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1101\/lm.60803"},{"key":"bibr241-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-003-1640-6"},{"key":"bibr242-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.physbeh.2010.04.027"},{"key":"bibr243-0269881120959637","volume-title":"A Liberated Mind: How to Pivot toward What Matters","author":"Hayes SC","year":"2019"},{"key":"bibr244-0269881120959637","volume-title":"Relational Frame Theory: A Post-Skinnerian Account of Human Language and Cognition","author":"Hayes SC","year":"2013"},{"key":"bibr245-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1348\/135910708X332936"},{"key":"bibr246-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1177\/0269881115598338"},{"key":"bibr247-0269881120959637","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2018.01549"},{"key":"bibr248-0269881120959637","volume-title":"Confrontation with the Unconscious: Jungian Depth Psychology and Psychedelic Experience","author":"Hill SJ","year":"2013"},{"key":"bibr249-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.socscimed.2017.03.024"},{"key":"bibr250-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1007\/s11013-016-9493-8"},{"key":"bibr251-0269881120959637","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2014.01133"},{"key":"bibr252-0269881120959637","volume-title":"Becoming the Iceman","author":"Hof W","year":"2011"},{"key":"bibr253-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0159023"},{"key":"bibr254-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbp006"},{"key":"bibr255-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-813323-1.00004-9"},{"key":"bibr256-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291717003397"},{"key":"bibr257-0269881120959637","first-page":"353","volume":"21","author":"Hunt HT","year":"2000","journal-title":"J Mind Behav"},{"key":"bibr258-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1037\/1089-2680.11.3.209"},{"key":"bibr259-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1038\/s41386-018-0076-y"},{"key":"bibr260-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-04840-2"},{"key":"bibr261-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.neures.2009.02.014"},{"key":"bibr262-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-3806(97)00149-1"},{"key":"bibr263-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1007\/s00360-017-1130-5"},{"key":"bibr264-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2004.04.040"},{"key":"bibr265-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1007\/s00127-013-0811-y"},{"key":"bibr266-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1093\/med:psych\/9780198523536.003.0011"},{"key":"bibr267-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-70474-6_17"},{"key":"bibr268-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.ynstr.2017.06.001"},{"key":"bibr269-0269881120959637","doi-asserted-by":"publisher","DOI":"10.4324\/9780203398470"},{"key":"bibr270-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2016.1031"},{"key":"bibr271-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2017.2943"},{"key":"bibr272-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.93.21.11962"},{"key":"bibr273-0269881120959637","volume-title":"The Origin of Consciousness in the Breakdown of the Bicameral Mind","author":"Jaynes J","year":"1976"},{"key":"bibr274-0269881120959637","doi-asserted-by":"publisher","DOI":"10.3390\/ijms17111918"},{"key":"bibr275-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2015.12.007"},{"key":"bibr276-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1159\/000026634"},{"key":"bibr277-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2011.01.016"},{"key":"bibr278-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.tics.2006.02.002"},{"key":"bibr279-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1080\/09540261.2018.1509544"},{"key":"bibr280-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1177\/0269881114548296"},{"key":"bibr281-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1177\/0269881108093587"},{"key":"bibr282-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1177\/0269881105053281"},{"key":"bibr283-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.b.30555"},{"key":"bibr284-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0905884106"},{"key":"bibr285-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.162.1.65"},{"key":"bibr286-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1111\/nyas.12261"},{"key":"bibr287-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-015-3951-9"},{"key":"bibr288-0269881120959637","first-page":"24S","volume":"21","author":"Jouvet M","year":"1999","journal-title":"Neuropsychoph"},{"key":"bibr289-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2018.06.034"},{"key":"bibr290-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2012.10.003"},{"key":"bibr291-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2005.11.005"},{"key":"bibr292-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1038\/mp.2014.148"},{"key":"bibr293-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.tins.2013.01.003"},{"key":"bibr294-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2826.2006.01422.x"},{"key":"bibr295-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2011.09.011"},{"key":"bibr296-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.110.080499"},{"key":"bibr297-0269881120959637","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph16245147"},{"key":"bibr298-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1097\/NMD.0000000000000362"},{"key":"bibr299-0269881120959637","volume-title":"Bifurcation Theory: An Introduction with Applications to Partial Differential Equations","volume":"156","author":"Kielh\u00f6fer H","year":"2011"},{"key":"bibr300-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.2005.00623.x"},{"key":"bibr301-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1037\/0022-006X.71.4.692"},{"key":"bibr302-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1503\/jpn.180087"},{"key":"bibr303-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5381.1974.tb08611.x"},{"key":"bibr304-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbs151"},{"key":"bibr305-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1993.01820160076009"},{"key":"bibr306-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1186\/cc8952"},{"key":"bibr307-0269881120959637","doi-asserted-by":"publisher","DOI":"10.3109\/15563657508988063"},{"key":"bibr308-0269881120959637","volume-title":"After the Ecstasy, the Laundry: How the Heart Grows Wise on the Spiritual Path","author":"Kornfield J","year":"2001"},{"key":"bibr309-0269881120959637","volume-title":"Stealing Fire: How Silicon Valley, the Navy SEALs, and Maverick Scientists Are Revolutionizing the Way We Live and Work","author":"Kotler S","year":"2017"},{"key":"bibr310-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychires.2015.07.020"},{"key":"bibr311-0269881120959637","doi-asserted-by":"publisher","DOI":"10.2174\/1573413713666170619092629"},{"key":"bibr312-0269881120959637","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2017.00814"},{"key":"bibr313-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1159\/000108125"},{"key":"bibr314-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2008.10.011"},{"key":"bibr315-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1007\/BF02245281"},{"key":"bibr316-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(94)91916-X"},{"key":"bibr317-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-017-4699-1"},{"key":"bibr318-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1177\/0269881119857204"},{"key":"bibr319-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1080\/15299732.2016.1194358"},{"key":"bibr320-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1080\/03085140500054545"},{"key":"bibr321-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1080\/13546805.2015.1137213"},{"key":"bibr322-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2015.05.049"},{"key":"bibr323-0269881120959637","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.08m04807"},{"key":"bibr324-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1097\/00005053-196312000-00007"},{"key":"bibr325-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2012.11.017"},{"key":"bibr326-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.23234"},{"key":"bibr327-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.22833"},{"key":"bibr328-0269881120959637","first-page":"104","volume":"4","author":"Lee H","year":"2007","journal-title":"Psychiat Invest"},{"key":"bibr329-0269881120959637","volume-title":"Acid Dreams: The Complete Social History of LSD: The CIA, the Sixties, and Beyond","author":"Lee MA","year":"1992"},{"key":"bibr330-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.concog.2015.11.012"},{"key":"bibr331-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1423936112"},{"key":"bibr332-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-016-4453-0"},{"key":"bibr333-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/S0893-133X(00)00126-3"},{"key":"bibr334-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/S0191-8869(96)00143-2"},{"key":"bibr335-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.concog.2019.05.008"},{"key":"bibr336-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1038\/s12276-018-0073-6"},{"key":"bibr337-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1971.03190200079023"},{"key":"bibr338-0269881120959637","doi-asserted-by":"publisher","DOI":"10.3389\/fnhum.2017.00316"},{"key":"bibr339-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1186\/s13041-018-0404-5"},{"key":"bibr340-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1037\/a0015127"},{"key":"bibr341-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2019.05.060"},{"key":"bibr342-0269881120959637","volume-title":"The Spiritual Exercises of St. Ignatius of Loyola","author":"Loyola SI","year":"2007"},{"key":"bibr343-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbw137"},{"key":"bibr344-0269881120959637","first-page":"155","volume":"17","author":"Lukoff D","year":"1985","journal-title":"J Transpersonal Psy"},{"key":"bibr345-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1097\/SMJ.0b013e318060072f"},{"key":"bibr346-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1177\/0022167818767511"},{"key":"bibr347-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2018.05.022"},{"key":"bibr348-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.164.5.637"},{"key":"bibr349-0269881120959637","unstructured":"Lyons T (2020) The acute and long-term effects of psilocybin in healthy volunteers, April. Available at: https:\/\/www.youtube.com\/watch?v=tSC-hu5BWTA"},{"key":"bibr350-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1177\/0269881117748902"},{"key":"bibr351-0269881120959637","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2018.01721"},{"key":"bibr352-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1177\/0269881111420188"},{"key":"bibr353-0269881120959637","first-page":"23","volume":"39","author":"Macmillan S","year":"2013","journal-title":"J Mediev Relig Cult"},{"key":"bibr354-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1038\/s41386-019-0324-9"},{"key":"bibr355-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.euroneuro.2020.02.001"},{"key":"bibr356-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1038\/nn.2529"},{"key":"bibr357-0269881120959637","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2018.00256"},{"key":"bibr358-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1080\/13811118.2017.1417185"},{"key":"bibr359-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1021\/acschemneuro.5b00031"},{"key":"bibr360-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1608282113"},{"key":"bibr361-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1080\/13651501.2017.1305111"},{"key":"bibr362-0269881120959637","volume-title":"Spiritual Bypassing: When Spirituality Disconnects Us from What Really Matters","author":"Masters RA","year":"2010"},{"key":"bibr363-0269881120959637","volume-title":"The Varieties of Psychedelic Experience: The Classic Guide to the Effects of LSD on the Human Psyche","author":"Masters RA","year":"2000"},{"key":"bibr364-0269881120959637","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.20552"},{"key":"bibr365-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1007\/BF02245187"},{"key":"bibr366-0269881120959637","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2015.01071"},{"key":"bibr367-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2014.12.019"},{"key":"bibr368-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.janxdis.2010.08.010"},{"key":"bibr369-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.neuro.22.1.105"},{"key":"bibr370-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1080\/10253890.2019.1631794"},{"key":"bibr371-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.116.195826"},{"key":"bibr372-0269881120959637","first-page":"13","volume-title":"Military Life: The Psychology of Serving in Peace and Combat: Operational Stress","author":"McGurk D","year":"2006"},{"key":"bibr373-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/0006-3223(94)00152-S"},{"key":"bibr374-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1017\/CBO9780511605529"},{"key":"bibr375-0269881120959637","doi-asserted-by":"crossref","DOI":"10.5040\/9798400642470","volume-title":"Dreams and Visions: How Religious Ideas Emerge in Sleep and Dreams","author":"McNamara P","year":"2016"},{"key":"bibr376-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1017\/9781316817094"},{"key":"bibr377-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1037\/13238-000"},{"key":"bibr378-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1385\/NMM:1:3:197"},{"key":"bibr379-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1002\/da.20627"},{"key":"bibr380-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.161.6.975"},{"key":"bibr381-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.coph.2011.02.007"},{"key":"bibr382-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1038\/npp.2009.176"},{"key":"bibr383-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/S0149-7634(99)00067-6"},{"key":"bibr384-0269881120959637","doi-asserted-by":"publisher","DOI":"10.5334\/jcr.174"},{"key":"bibr385-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.160.1.90"},{"key":"bibr386-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1177\/0269881116675511"},{"key":"bibr387-0269881120959637","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2016.00299"},{"key":"bibr388-0269881120959637","volume-title":"Quantum Change: When Epiphanies and Sudden Insights Transform Ordinary Lives","author":"Miller WR","year":"2001"},{"key":"bibr389-0269881120959637","doi-asserted-by":"publisher","DOI":"10.3389\/fnhum.2017.00245"},{"key":"bibr390-0269881120959637","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2018.01475"},{"key":"bibr391-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1111\/bdi.12439"},{"key":"bibr392-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1037\/0021-843X.94.3.384"},{"key":"bibr393-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1007\/s12035-012-8232-6"},{"key":"bibr394-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-04496-y"},{"key":"bibr395-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2014.07.041"},{"key":"bibr396-0269881120959637","doi-asserted-by":"publisher","DOI":"10.4088\/PCC.18l02355"},{"key":"bibr397-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.schbul.a033442"},{"key":"bibr398-0269881120959637","first-page":"2425","volume":"123","author":"M\u00f8ller P","year":"2003","journal-title":"Tidsskrift for den Norske laegeforening: tidsskrift for praktisk medicin, ny raekke"},{"key":"bibr399-0269881120959637","volume-title":"The Myth of the Chemical Cure: A Critique of Psychiatric Drugs","author":"Moncrieff J","year":"2008"},{"key":"bibr400-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.pnpbp.2006.02.013"},{"key":"bibr401-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-70474-6_13"},{"key":"bibr402-0269881120959637","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v67n1110"},{"key":"bibr403-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-70474-6_7"},{"key":"bibr404-0269881120959637","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.33746"},{"key":"bibr405-0269881120959637","doi-asserted-by":"publisher","DOI":"10.12740\/PP\/OnlineFirst\/63514"},{"key":"bibr406-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2014.08.009"},{"key":"bibr407-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3940(80)90242-6"},{"key":"bibr408-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1097\/FBP.0000000000000459"},{"key":"bibr409-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-019-05445-3"},{"key":"bibr410-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1176\/appi.neuropsych.11090214"},{"key":"bibr411-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1152\/ajplegacy.1971.220.6.1746"},{"key":"bibr412-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtherbio.2016.03.010"},{"key":"bibr413-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpain.2008.06.007"},{"key":"bibr414-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1177\/0022167817714692."},{"key":"bibr415-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1002\/syn.20460"},{"key":"bibr416-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2019.02.018"},{"key":"bibr417-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0075426"},{"key":"bibr418-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1017\/CBO9781139941297.017"},{"key":"bibr419-0269881120959637","first-page":"309","volume-title":"Handbook of Behavioral Neuroscience","volume":"31","author":"Neugebauer V","year":"2020"},{"key":"bibr420-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1097\/NMD.0000000000000523"},{"key":"bibr421-0269881120959637","unstructured":"Nichols CD, Nichols DE (2019) DMT in the Mammalian Brain: A Critical Appraisal. Available at: https:\/\/www.aliusresearch.org\/nichols-nichols-endogenous-dmt.html"},{"key":"bibr422-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1124\/pr.115.011478"},{"key":"bibr423-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3940(95)11805-7"},{"key":"bibr424-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-8993(00)03020-1"},{"key":"bibr425-0269881120959637","doi-asserted-by":"publisher","DOI":"10.4103\/0976-3147.193532"},{"key":"bibr426-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1080\/02791072.2017.1312643"},{"key":"bibr427-0269881120959637","doi-asserted-by":"publisher","DOI":"10.3389\/fnhum.2016.00269"},{"key":"bibr428-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2020.03.020"},{"key":"bibr429-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1038\/nrn3530"},{"key":"bibr430-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijdevneu.2013.10.007"},{"key":"bibr431-0269881120959637","first-page":"203","volume":"361","author":"Olivier B","year":"1990","journal-title":"Prog Clin Biol Res"},{"key":"bibr432-0269881120959637","volume-title":"Celibacy and Religious Traditions","author":"Olson C","year":"2008"},{"key":"bibr433-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1177\/1179069518800508"},{"key":"bibr434-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1080\/10503307.2019.1633484"},{"key":"bibr435-0269881120959637","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2018.00447"},{"key":"bibr436-0269881120959637","doi-asserted-by":"publisher","DOI":"10.4159\/9780674915510"},{"key":"bibr437-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1590\/1516-4446-2014-1496"},{"key":"bibr438-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1007\/s007020170077"},{"key":"bibr439-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.b.30197"},{"key":"bibr440-0269881120959637","first-page":"787","volume":"256","author":"Owens MJ","year":"1991","journal-title":"J Pharmacol Exp Ther"},{"key":"bibr441-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.159.3.419"},{"key":"bibr442-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2016.06.002"},{"key":"bibr443-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1017\/S0954579417001274"},{"key":"bibr444-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1053\/comp.2003.50017"},{"key":"bibr445-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.concog.2016.05.010"},{"key":"bibr446-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.113.141937"},{"key":"bibr447-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1177\/0269881120909409"},{"key":"bibr448-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.physbeh.2011.01.006"},{"key":"bibr449-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1093\/acprof:oso\/9780198717959.001.0001"},{"key":"bibr450-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2006.09.050"},{"key":"bibr451-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2015.01.029"},{"key":"bibr452-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1038\/sj.npp.1300819"},{"key":"bibr453-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-002-1357-y"},{"key":"bibr454-0269881120959637","first-page":"5","volume":"3","author":"Perry JW","year":"1977","journal-title":"J Alter St Conscious"},{"key":"bibr455-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1098\/rsif.2014.0873"},{"key":"bibr456-0269881120959637","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2018.00132"},{"key":"bibr457-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2016.3803"},{"key":"bibr458-0269881120959637","doi-asserted-by":"publisher","DOI":"10.3389\/fnbeh.2015.00048"},{"key":"bibr459-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1038\/npp.2017.80"},{"key":"bibr460-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1038\/npp.2016.84"},{"key":"bibr461-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1093\/ijnp\/pyx047"},{"key":"bibr462-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1017\/S0140525X17002138"},{"key":"bibr463-0269881120959637","volume-title":"How to Change Your Mind: What the New Science of Psychedelics Teaches Us about Consciousness, Dying, Addiction, Depression, and Transcendence","author":"Pollan M","year":"2019"},{"key":"bibr464-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1017\/S0140525X1700214X"},{"key":"bibr465-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1038\/sj.mp.4001511"},{"key":"bibr466-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2003.10.008"},{"key":"bibr467-0269881120959637","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.35082"},{"key":"bibr468-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2016.12.030"},{"key":"bibr469-0269881120959637","first-page":"711","volume-title":"Handbook of Behavioral Neuroscience","volume":"31","author":"Quednow BB","year":"2020"},{"key":"bibr470-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1038\/npp.2011.228"},{"key":"bibr471-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/17.4.555"},{"key":"bibr472-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/20.1.191"},{"key":"bibr473-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-7893.2011.00281.x"},{"key":"bibr474-0269881120959637","volume-title":"Understanding Religious Conversion","author":"Rambo LR","year":"1993"},{"key":"bibr475-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2014.07.024"},{"key":"bibr476-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1038\/4580"},{"key":"bibr477-0269881120959637","volume-title":"Serotonin Receptors in Neurobiology","author":"Raote I","year":"2007"},{"key":"bibr478-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1038\/sj.npp.1301553"},{"key":"bibr479-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1001\/archgenpsychiatry.2009.176"},{"key":"bibr480-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.euroneuro.2016.04.008"},{"key":"bibr481-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/0014-2999(86)90014-2"},{"key":"bibr482-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sby129"},{"key":"bibr483-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1007\/s00127-008-0359-4"},{"key":"bibr484-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1111\/eip.12451"},{"key":"bibr485-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/S0893-133X(01)00366-9"},{"key":"bibr486-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.2005.04251.x"},{"key":"bibr487-0269881120959637","first-page":"185","volume":"14","author":"Rhodes RF","year":"1987","journal-title":"Jpn J Relig Stud"},{"key":"bibr488-0269881120959637","doi-asserted-by":"publisher","DOI":"10.7312\/columbia\/9780231174060.001.0001"},{"key":"bibr489-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1038\/nrn1409"},{"key":"bibr490-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1038\/sj.npp.1301305"},{"key":"bibr491-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2013.01.012"},{"key":"bibr492-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-3057(97)00509-1"},{"key":"bibr493-0269881120959637","doi-asserted-by":"publisher","DOI":"10.3389\/fnbeh.2018.00233"},{"key":"bibr494-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.beth.2017.08.008"},{"key":"bibr495-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1023\/A:1007895817502"},{"key":"bibr496-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-010-2004-7"},{"key":"bibr497-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1177\/0269881119855974"},{"key":"bibr498-0269881120959637","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2017.00974"},{"key":"bibr499-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1017\/S0140525X17002151"},{"key":"bibr500-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1177\/0269881116675512"},{"key":"bibr501-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1002\/da.10059"},{"key":"bibr502-0269881120959637","volume-title":"Reality Is Not What It Seems: The Journey to Quantum Gravity","author":"Rovelli C","year":"2018"},{"key":"bibr503-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2017.12.040"},{"key":"bibr504-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1007\/BF00441948"},{"key":"bibr505-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtherbio.2004.12.001"},{"key":"bibr506-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1254\/jjp.89.89"},{"key":"bibr507-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8223(21)14634-6"},{"key":"bibr508-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0773.1998.tb01410.x"},{"key":"bibr509-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-183X.2011.00708.x"},{"key":"bibr510-0269881120959637","unstructured":"Salvation (n.d.) [Def. 3 a.b.] Merriam-Webster.com. Available at: https:\/\/www.merriam-webster.com\/dictionary\/salvation (accessed 13 August 2019)."},{"key":"bibr511-0269881120959637","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2018.00007"},{"key":"bibr512-0269881120959637","first-page":"1","volume":"42","author":"Savage C","year":"1955","journal-title":"Psychoanal Rev"},{"key":"bibr513-0269881120959637","first-page":"405","volume":"17","author":"Savage C","year":"1956","journal-title":"J Clin Exp Psychopat"},{"key":"bibr514-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-8993(03)02832-4"},{"key":"bibr515-0269881120959637","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2018.00177"},{"key":"bibr516-0269881120959637","doi-asserted-by":"publisher","DOI":"10.2174\/157015912799362724"},{"key":"bibr517-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0216643"},{"key":"bibr518-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1038\/npp.2014.38"},{"key":"bibr519-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2014.11.015"},{"key":"bibr520-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1080\/17522439.2016.1264992"},{"key":"bibr521-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2016.09.032"},{"key":"bibr522-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.187.2.101"},{"key":"bibr523-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.191.51.s9"},{"key":"bibr524-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbt134"},{"key":"bibr525-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1002\/wps.20369"},{"key":"bibr526-0269881120959637","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2019.00138"},{"key":"bibr527-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.tics.2013.09.007"},{"key":"bibr528-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2010.09.039"},{"key":"bibr529-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1093\/oso\/9780199252923.001.0001"},{"key":"bibr530-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2008.11.036"},{"key":"bibr531-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1080\/02791072.1986.10472368"},{"key":"bibr532-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1017\/S0140525X17001893"},{"key":"bibr533-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1007\/s12576-019-00703-7"},{"key":"bibr534-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2019-029342"},{"key":"bibr535-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcbs.2019.11.002"},{"key":"bibr536-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2019.04.009"},{"key":"bibr537-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2182-17.2018"},{"key":"bibr538-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2019.03.056"},{"key":"bibr539-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijdevneu.2017.10.005"},{"issue":"7","key":"bibr540-0269881120959637","volume-title":"The Sun Dance of the Plains Indians: Its Development and Diffusion","volume":"16","author":"Spier L","year":"1921"},{"key":"bibr541-0269881120959637","volume-title":"Mysticism and Philosophy","author":"Stace WT","year":"1960"},{"key":"bibr542-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1017\/S1092852918001013"},{"key":"bibr543-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(83)92590-4"},{"key":"bibr544-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1080\/13674670903357844"},{"key":"bibr545-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1503\/jpn.180190"},{"key":"bibr546-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbn176"},{"key":"bibr547-0269881120959637","first-page":"73","volume-title":"Stress: Concepts, Cognition, Emotion, and Behavior","author":"Steptoe A","year":"2016"},{"key":"bibr548-0269881120959637","volume-title":"Handbook of Life Stress, Cognition, and Health","author":"Sterling P","year":"1988"},{"key":"bibr549-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1111\/jne.12374"},{"key":"bibr550-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1097\/00005053-198410000-00001"},{"key":"bibr551-0269881120959637","volume-title":"DMT: The Spirit Molecule: A Doctor\u2019s Revolutionary Research into the Biology of Near-Death and Mystical Experiences","author":"Strassman RJ","year":"2000"},{"key":"bibr552-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0030800"},{"key":"bibr553-0269881120959637","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2012.00041"},{"key":"bibr554-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3223(96)00499-4"},{"key":"bibr555-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.concog.2013.03.007"},{"key":"bibr556-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0012650"},{"key":"bibr557-0269881120959637","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2016.00423"},{"key":"bibr558-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-017-4613-x"},{"key":"bibr559-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.jgg.2013.06.004"},{"key":"bibr560-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.22562"},{"key":"bibr561-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/0014-2999(95)00620-6"},{"key":"bibr562-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/S1359-1789(98)00005-6"},{"key":"bibr563-0269881120959637","first-page":"377","volume-title":"Handbook of Behavioral Neuroscience","volume":"31","author":"Teran FA","year":"2020"},{"key":"bibr564-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpr.2017.03.007"},{"key":"bibr565-0269881120959637","volume-title":"Poster presented at Insight 2019","author":"Timmermann C","year":"2019"},{"key":"bibr566-0269881120959637","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2018.01424"},{"key":"bibr567-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.beth.2017.05.005"},{"key":"bibr568-0269881120959637","doi-asserted-by":"crossref","first-page":"1456","DOI":"10.1176\/ajp.156.9.1456","volume":"156","author":"Turecki G","year":"1999","journal-title":"Am J Psychiatry"},{"key":"bibr569-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2004.12.002"},{"key":"bibr570-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.17-08-02785.1997"},{"key":"bibr571-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1111\/acps.12714"},{"key":"bibr572-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(01)07100-8"},{"key":"bibr573-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291701004044"},{"key":"bibr574-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0040187"},{"key":"bibr575-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291711001826"},{"key":"bibr576-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbs050"},{"key":"bibr577-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-8993(99)02307-0"},{"key":"bibr578-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2007.07030423"},{"key":"bibr579-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1002\/syn.21750"},{"key":"bibr580-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2020.01.033"},{"key":"bibr581-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/S0893-133X(96)00246-1"},{"key":"bibr582-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1097\/00001756-199812010-00024"},{"key":"bibr583-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1038\/tp.2015.67"},{"key":"bibr584-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1525\/aa.1956.58.2.02a00040"},{"key":"bibr585-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1177\/0022167882223004"},{"key":"bibr586-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1080\/09540261.2018.1474088"},{"key":"bibr587-0269881120959637","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2018.00303"},{"key":"bibr588-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2015.07.018"},{"key":"bibr589-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1177\/0022167817709585"},{"key":"bibr590-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcbs.2019.12.004"},{"key":"bibr591-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1038\/pr.2013.66"},{"key":"bibr592-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1007\/s002130050605"},{"key":"bibr593-0269881120959637","volume-title":"Millennialism, Persecution, and Violence: Historical Cases","author":"Wessinger C","year":"2000"},{"key":"bibr594-0269881120959637","volume-title":"Anatomy of an Epidemic: Magic Bullets, Psychiatric Drugs, and the Astonishing Rise of Mental Illness in America","author":"Whitaker R","year":"2011"},{"key":"bibr595-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1002\/jclp.20001"},{"key":"bibr596-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1159\/000457960"},{"key":"bibr597-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.cognition.2017.05.018"},{"key":"bibr598-0269881120959637","volume-title":"The Big Book of Alcoholics Anonymous (Including 12 Steps, Guides & Prayers)","author":"Wilson B","year":"2015"},{"key":"bibr599-0269881120959637","doi-asserted-by":"crossref","DOI":"10.1093\/oso\/9780195151381.001.0001","volume-title":"Asceticism","author":"Wimbush VL","year":"2002"},{"key":"bibr600-0269881120959637","doi-asserted-by":"publisher","DOI":"10.13140\/RG.2.1.4381.2720."},{"key":"bibr601-0269881120959637","first-page":"129","volume-title":"Collected Papers: Through Pediatric to Psychoanalysis","author":"Winnicott D","year":"1935"},{"key":"bibr602-0269881120959637","volume-title":"Ode Intimations of Immortality from Recollections of Early Childhood","author":"Woodsworth W","year":"1884"},{"key":"bibr603-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-7893.2009.00116.x"},{"key":"bibr604-0269881120959637","volume-title":"Depression and Other Common Mental Disorders: Global Health Estimates","author":"World Health Organization","year":"2017"},{"key":"bibr605-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1007\/BF02244319"},{"key":"bibr606-0269881120959637","first-page":"2288","volume":"11","author":"Xiang M","year":"2019","journal-title":"Am J Transl Res"},{"key":"bibr607-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2016.02.020"},{"key":"bibr608-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0048741"},{"key":"bibr609-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1007\/BF02246047"},{"key":"bibr610-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-018-5119-x"},{"key":"bibr611-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1093\/ijnp\/pyy036"},{"key":"bibr612-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/0091-3057(95)00045-X"},{"key":"bibr613-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-017-4684-8"},{"key":"bibr614-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.108.143461"},{"key":"bibr615-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/0014-2999(92)90304-M"},{"key":"bibr616-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1001\/archgenpsychiatry.2010.101"},{"key":"bibr617-0269881120959637","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2017.02350"},{"key":"bibr618-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2012.06.007"},{"key":"bibr619-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2016.04.033"},{"key":"bibr620-0269881120959637","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2015.00225"},{"key":"bibr621-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1038\/tp.2016.238"},{"key":"bibr622-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-8993(01)02283-1"},{"key":"bibr623-0269881120959637","doi-asserted-by":"crossref","unstructured":"Zhao X, Meyers KT, Marballi KK, et al. (2019) Environment rapidly upregulates serotonin 2A receptor expression via the immediate early gene Egr3. bioRxiv, 634410.","DOI":"10.1101\/634410"},{"key":"bibr624-0269881120959637","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2019.107747"}],"container-title":["Journal of Psychopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0269881120959637","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0269881120959637","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0269881120959637","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:10:23Z","timestamp":1777507823000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0269881120959637"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,11]]},"references-count":624,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,4]]}},"alternative-id":["10.1177\/0269881120959637"],"URL":"https:\/\/doi.org\/10.1177\/0269881120959637","relation":{},"ISSN":["0269-8811","1461-7285"],"issn-type":[{"value":"0269-8811","type":"print"},{"value":"1461-7285","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,11,11]]}}}