{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T10:06:19Z","timestamp":1790417179163,"version":"4.1.0"},"reference-count":41,"publisher":"SAGE Publications","issue":"9","license":[{"start":{"date-parts":[[2021,3,28]],"date-time":"2021-03-28T00:00:00Z","timestamp":1616889600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100006309","name":"Riisfort Fonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006309","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002739","name":"Aarhus Universitets Forskningsfond","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002739","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004836","name":"Det Frie Forskningsr\u00e5d","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004836","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007605","name":"aarhus universitet","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007605","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Psychopharmacol"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>The six-item version of the Positive and Negative Syndrome Scale (PANSS-6) has shown promise as a brief measure of the severity of core symptoms of schizophrenia. However, since all prior analyses of the PANSS-6 were based on data extracted from studies using the full 30-item PANSS (PANSS-30), it remains unknown whether it is possible to obtain valid information for the PANSS-6 ratings via a brief interview, such as the Simplified Negative and Positive Symptoms Interview (SNAPSI).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims:<\/jats:title>\n                    <jats:p>We aimed to validate the PANSS-6 ratings obtained via the SNAPSI using the PANSS-6 scores extracted from the PANSS-30 ratings obtained via the comprehensive Structured Clinical Interview for PANSS (SCI-PANSS) as the gold-standard reference.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>The PANSS-6 ratings based on the SNAPSI and the PANSS-30 ratings based on the SCI-PANSS were conducted by independent raters with established inter-rater reliability.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Seventy-seven inpatients with schizophrenia ( M\n                      <jats:sub>age<\/jats:sub>\n                      \u2009=\u200935.1\u2009\u00b1\u200911.7\u2009years; males\u2009=\u200957%; paranoid schizophrenia\u2009=\u200975%) participated in the study. The intraclass correlation coefficient (ICC) of the PANSS-6 total scores obtained using the SNAPSI and the PANSS-30-derived PANSS-6 total scores via the SCI-PANSS was 0.77 ( p\u2009&lt;\u20090.001). The ICC for the PANSS-6 total score and the PANSS-30-derived PANSS-8 (Andreasen\u2019s remission criteria) was 0.75 ( p\u2009&lt;\u20090.001). Spearman\u2019s rank correlation coefficient for changes in PANSS-6 total scores via the SNAPSI and changes in PANSS-30-derived PANSS-6 total scores was 0.70 ( p\u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Using the SNAPSI to rate the PANSS-6 enables a focused and brief assessment of the severity of core symptoms of schizophrenia, which facilitates measurement-based care and clinical decision making in the treatment of schizophrenia.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0269881121996890","type":"journal-article","created":{"date-parts":[[2021,3,29]],"date-time":"2021-03-29T02:47:10Z","timestamp":1616986030000},"page":"1081-1090","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":20,"title":["Clinical validation of ratings on the six-item Positive and Negative Syndrome Scale obtained via the Simplified Negative and Positive Symptoms Interview"],"prefix":"10.1177","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6221-9601","authenticated-orcid":false,"given":"Pernille","family":"K\u00f8lb\u00e6k","sequence":"first","affiliation":[{"name":"Psychosis Research Unit, Aarhus University Hospital \u2013 Psychiatry, Aarhus, Denmark"},{"name":"Department of Clinical Medicine, Aarhus University, Aarhus, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Dines","sequence":"additional","affiliation":[{"name":"Psychosis Research Unit, Aarhus University Hospital \u2013 Psychiatry, Aarhus, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tine","family":"Holm","sequence":"additional","affiliation":[{"name":"Psychosis Research Unit, Aarhus University Hospital \u2013 Psychiatry, Aarhus, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne B","family":"Blicher","sequence":"additional","affiliation":[{"name":"Psychosis Research Unit, Aarhus University Hospital \u2013 Psychiatry, Aarhus, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rune D","family":"S\u00f8rensen","sequence":"additional","affiliation":[{"name":"Psychosis Research Unit, Aarhus University Hospital \u2013 Psychiatry, Aarhus, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathrine M","family":"O\u2019Leary","sequence":"additional","affiliation":[{"name":"Psychosis Research Unit, Aarhus University Hospital \u2013 Psychiatry, Aarhus, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra G","family":"Feller","sequence":"additional","affiliation":[{"name":"Psychosis Research Unit, Aarhus University Hospital \u2013 Psychiatry, Aarhus, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chanette W","family":"Buus","sequence":"additional","affiliation":[{"name":"Psychosis Research Unit, Aarhus University Hospital \u2013 Psychiatry, Aarhus, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cecilie M","family":"Nielsen","sequence":"additional","affiliation":[{"name":"Psychosis Research Unit, Aarhus University Hospital \u2013 Psychiatry, Aarhus, Denmark"},{"name":"Department of Clinical Medicine, Aarhus University, Aarhus, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Opler","sequence":"additional","affiliation":[{"name":"MedAvante-ProPhase Inc., New York, USA"},{"name":"Department of Psychiatry, New York University School of Medicine, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ole","family":"Mors","sequence":"additional","affiliation":[{"name":"Psychosis Research Unit, Aarhus University Hospital 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