{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,10]],"date-time":"2026-05-10T15:26:17Z","timestamp":1778426777496,"version":"3.51.4"},"reference-count":79,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T00:00:00Z","timestamp":1764201600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T00:00:00Z","timestamp":1764201600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100009473","name":"Universidad de M\u00e1laga","doi-asserted-by":"publisher","award":["C\u00e1tedra Imbrain: Neurociencia Integrada y Bienest"],"award-info":[{"award-number":["C\u00e1tedra Imbrain: Neurociencia Integrada y Bienest"]}],"id":[{"id":"10.13039\/100009473","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006461","name":"Agencia de Innovaci\u00f3n y Desarrollo de Andaluc\u00eda","doi-asserted-by":"publisher","award":["EMERGIA 2020-39318"],"award-info":[{"award-number":["EMERGIA 2020-39318"]}],"id":[{"id":"10.13039\/501100006461","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006461","name":"Agencia de Innovaci\u00f3n y Desarrollo de Andaluc\u00eda","doi-asserted-by":"publisher","award":["ProyExcel_00613"],"award-info":[{"award-number":["ProyExcel_00613"]}],"id":[{"id":"10.13039\/501100006461","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["PI24\/ 01816"],"award-info":[{"award-number":["PI24\/ 01816"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"name":"IBIMA","award":["Funding for open access charge"],"award-info":[{"award-number":["Funding for open access charge"]}]},{"DOI":"10.13039\/501100013697","name":"Direcci\u00f3n Nacional de Innovaci\u00f3n, Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["CONSOLIDACION INVESTIGADORA (CNS2022-136008)"],"award-info":[{"award-number":["CONSOLIDACION INVESTIGADORA (CNS2022-136008)"]}],"id":[{"id":"10.13039\/501100013697","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006310","name":"Medicinska Forskningsr\u00e5det","doi-asserted-by":"publisher","award":["62X-00715-50-3"],"award-info":[{"award-number":["62X-00715-50-3"]}],"id":[{"id":"10.13039\/501100006310","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004200","name":"Olle Engkvists Stiftelse","doi-asserted-by":"publisher","award":["2018 and 2021"],"award-info":[{"award-number":["2018 and 2021"]}],"id":[{"id":"10.13039\/501100004200","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003792","name":"Hj\u00e4rnfonden","doi-asserted-by":"publisher","award":["F02018-0286"],"award-info":[{"award-number":["F02018-0286"]}],"id":[{"id":"10.13039\/501100003792","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003792","name":"Hj\u00e4rnfonden","doi-asserted-by":"publisher","award":["F02019-0296"],"award-info":[{"award-number":["F02019-0296"]}],"id":[{"id":"10.13039\/501100003792","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Psychopharmacol"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Neuropeptide Y1 receptor (NPY1R) heteroreceptor complexes with galanin receptor 2 (GALR2) and Tropomyosin receptor kinase B (TrkB) contribute to neuroplasticity and mood regulation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims:<\/jats:title>\n                    <jats:p>To determine whether transient intracerebroventricular (ICV) knockdown of NPY1R is sufficient to alter hippocampal neurogenesis and depressive-like behaviour.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Adult Sprague-Dawley rats received a single ICV injection of Accell Smart-Pool small interfering RNA (siRNA) targeting NPY1R or a scrambled control. NPY1R protein levels, NPY1R-GALR2 and NPY1R-TrkB complexes (in situ proximity ligation), proliferating cell nuclear antigen (PCNA) counts, brain-derived neurotrophic factor (BDNF) expression and forced-swim behaviour were assessed 6, 8 and 10\u2009days post-injection in the ventral hippocampus.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      ICV siRNA significantly reduced NPY1R immunoreactivity (peak at day 8; p&lt;0.05) and lowered NPY1R-GALR2 and NPY1R-TrkB heteroreceptor complexes (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt;0.01 and\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt;0.001, respectively). PCNA-positive cell numbers and BDNF optical density were unchanged at all time points. Forced-swim immobility, climbing and swimming times likewise remained unaltered.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Transient ICV knockdown effectively disrupts NPY1R heteroreceptor complexes but fails to impact neurogenesis or depressive-like behaviour, indicating compensatory mechanisms that preserve hippocampal plasticity. Within the time window and conditions tested, transient NPY1R knockdown disrupted GALR2\/TrkB heteroreceptor complexes without altering neurogenesis or depressive-like behaviour, delineating receptor-complex-level target engagement and motivating studies using sustained and circuit-specific manipulations to assess therapeutic potential.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/02698811251389528","type":"journal-article","created":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T11:51:57Z","timestamp":1764244317000},"page":"1462-1475","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Intracerebroventricular knockdown of NPY1R disrupts NPY1R-GALR2\/TrkB heteroreceptor complexes without affecting neuroplasticity or depressive-like behaviour"],"prefix":"10.1177","volume":"39","author":[{"given":"Isabel","family":"Moreno-Madrid","sequence":"first","affiliation":[{"name":"Instituto de Investigaci\u00f3n Biom\u00e9dica de M\u00e1laga y Plataforma en Nanomedicina\u2013IBIMA Plataforma Bionand, Malaga, Spain"},{"name":"Universidad de M\u00e1laga, ImbrainLab, Facultad de Medicina, M\u00e1laga, Spain"},{"name":"Universidad de M\u00e1laga, Receptomics and Brain disorders lab, Edificio Lopez-Pe\u00f1alver, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"Arrabal-G\u00f3mez","sequence":"additional","affiliation":[{"name":"Instituto de Investigaci\u00f3n Biom\u00e9dica de M\u00e1laga y Plataforma en Nanomedicina\u2013IBIMA Plataforma Bionand, Malaga, Spain"},{"name":"Universidad de M\u00e1laga, ImbrainLab, Facultad de Medicina, M\u00e1laga, Spain"},{"name":"Hospital Regional Universitario de M\u00e1laga, Unit of Neurology, M\u00e1laga, Spain"},{"name":"Universidad de M\u00e1laga, Facultad de Psicolog\u00eda, Ampliaci\u00f3n de Teatinos, M\u00e1laga, Spain"},{"name":"Vithas M\u00e1laga, Grupo Hospitalario Vithas, M\u00e1laga, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0120-481X","authenticated-orcid":false,"given":"Jes\u00fas","family":"Romero-Imbroda","sequence":"additional","affiliation":[{"name":"Instituto de Investigaci\u00f3n Biom\u00e9dica de M\u00e1laga y Plataforma en Nanomedicina\u2013IBIMA Plataforma Bionand, Malaga, Spain"},{"name":"Universidad de M\u00e1laga, ImbrainLab, Facultad de Medicina, M\u00e1laga, Spain"},{"name":"Hospital Regional Universitario de M\u00e1laga, Unit of Neurology, M\u00e1laga, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amelia","family":"D\u00edaz-Casares","sequence":"additional","affiliation":[{"name":"Instituto de Investigaci\u00f3n Biom\u00e9dica de M\u00e1laga y Plataforma en Nanomedicina\u2013IBIMA Plataforma Bionand, Malaga, Spain"},{"name":"Universidad de M\u00e1laga, ImbrainLab, Facultad de Medicina, M\u00e1laga, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kjell","family":"Fuxe","sequence":"additional","affiliation":[{"name":"Karolinska Institutet, Department of Neuroscience, Stockholm, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dasiel","family":"Borroto-Escuela","sequence":"additional","affiliation":[{"name":"Instituto de Investigaci\u00f3n Biom\u00e9dica de M\u00e1laga y Plataforma en Nanomedicina\u2013IBIMA Plataforma Bionand, Malaga, Spain"},{"name":"Universidad de M\u00e1laga, Receptomics and Brain disorders lab, Edificio Lopez-Pe\u00f1alver, Spain"},{"name":"Karolinska Institutet, Department of Neuroscience, Stockholm, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro","family":"Serrano-Castro","sequence":"additional","affiliation":[{"name":"Instituto de Investigaci\u00f3n Biom\u00e9dica de M\u00e1laga y Plataforma en Nanomedicina\u2013IBIMA Plataforma Bionand, Malaga, Spain"},{"name":"Universidad de M\u00e1laga, ImbrainLab, Facultad de Medicina, M\u00e1laga, Spain"},{"name":"Hospital Regional Universitario de M\u00e1laga, Unit of Neurology, M\u00e1laga, Spain"},{"name":"Vithas M\u00e1laga, Grupo Hospitalario Vithas, M\u00e1laga, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0922-4900","authenticated-orcid":false,"given":"Manuel","family":"Narv\u00e1ez","sequence":"additional","affiliation":[{"name":"Instituto de Investigaci\u00f3n Biom\u00e9dica de M\u00e1laga y Plataforma en Nanomedicina\u2013IBIMA Plataforma Bionand, Malaga, Spain"},{"name":"Universidad de M\u00e1laga, ImbrainLab, Facultad de Medicina, M\u00e1laga, Spain"},{"name":"Vithas M\u00e1laga, Grupo Hospitalario Vithas, M\u00e1laga, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,11,27]]},"reference":[{"key":"e_1_3_2_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.30944"},{"key":"e_1_3_2_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/14728222.2024.2342524"},{"key":"e_1_3_2_4_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnana.2018.00044"},{"key":"e_1_3_2_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2006.06.033"},{"key":"e_1_3_2_6_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.202400087R"},{"key":"e_1_3_2_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.npp.1300820"},{"key":"e_1_3_2_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2018.03.015"},{"key":"e_1_3_2_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/npp.2013.5"},{"key":"e_1_3_2_10_1","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2017.00037"},{"key":"e_1_3_2_11_1","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2017.00309"},{"key":"e_1_3_2_12_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2022.820210"},{"key":"e_1_3_2_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.30092"},{"key":"e_1_3_2_14_1","doi-asserted-by":"publisher","DOI":"10.1080\/14728222.2024.2342517"},{"key":"e_1_3_2_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-6147(00)01446-2"},{"key":"e_1_3_2_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2021.01.034"},{"key":"e_1_3_2_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2016.07.010"},{"key":"e_1_3_2_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2021.05.008"},{"key":"e_1_3_2_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/npp.2011.230"},{"key":"e_1_3_2_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euroneuro.2017.11.006"},{"key":"e_1_3_2_21_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0088294"},{"key":"e_1_3_2_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-005-0093-5"},{"key":"e_1_3_2_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/hipo.20765"},{"key":"e_1_3_2_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2023.114433"},{"key":"e_1_3_2_25_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.52939"},{"key":"e_1_3_2_26_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.34202"},{"key":"e_1_3_2_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2017.08.005"},{"key":"e_1_3_2_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2009.02.033"},{"key":"e_1_3_2_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2005.03057.x"},{"key":"e_1_3_2_30_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1471-4159.2003.01895.x"},{"key":"e_1_3_2_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0028-3908(00)00009-5"},{"key":"e_1_3_2_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/hipo.20264"},{"issue":"16","key":"e_1_3_2_33_1","article-title":"Brain galanin system genes interact with life stresses in depression-related phenotypes","volume":"111","author":"Juhasz G","year":"2014","unstructured":"Juhasz G, Hullam G, Eszlari N, et al. (2014) Brain galanin system genes interact with life stresses in depression-related phenotypes. Proceedings of the National Academy of Sciences of the United States of America 111(16): E1666\u2013E1673.","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"e_1_3_2_34_1","doi-asserted-by":"publisher","DOI":"10.1242\/dmm.050759"},{"key":"e_1_3_2_35_1","doi-asserted-by":"publisher","DOI":"10.1037\/0735-7044.118.6.1365"},{"key":"e_1_3_2_36_1","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a019026"},{"key":"e_1_3_2_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5381.2012.02223.x"},{"key":"e_1_3_2_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneumeth.2021.109452"},{"key":"e_1_3_2_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.npep.2013.10.014"},{"key":"e_1_3_2_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euroneuro.2006.03.003"},{"key":"e_1_3_2_41_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.npp.1301660"},{"key":"e_1_3_2_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2023.113595"},{"key":"e_1_3_2_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.npep.2004.12.011"},{"key":"e_1_3_2_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.npep.2008.04.009"},{"key":"e_1_3_2_45_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12264-019-00412-6"},{"key":"e_1_3_2_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2013.11.009"},{"key":"e_1_3_2_47_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.201600781r"},{"key":"e_1_3_2_48_1","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2019.00363"},{"key":"e_1_3_2_49_1","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines10061297"},{"key":"e_1_3_2_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2011.06.030"},{"key":"e_1_3_2_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2013.01.037"},{"key":"e_1_3_2_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiotec.2011.10.003"},{"key":"e_1_3_2_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2020.108070"},{"key":"e_1_3_2_54_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00429-015-1153-1"},{"key":"e_1_3_2_55_1","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2018.00119"},{"key":"e_1_3_2_56_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-0716-1522-5_9"},{"key":"e_1_3_2_57_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00429-014-0788-7"},{"key":"e_1_3_2_58_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9861(19990705)409:3<469::AID-CNE10>3.0.CO;2-Q"},{"key":"e_1_3_2_59_1","doi-asserted-by":"publisher","DOI":"10.1002\/jnr.22770"},{"key":"e_1_3_2_60_1","volume-title":"The Rat Brain in Stereotaxic Coordinates: Hard Cover Edition","author":"Paxinos G","year":"2006","unstructured":"Paxinos G, Watson C (2006) The Rat Brain in Stereotaxic Coordinates: Hard Cover Edition. Elsevier."},{"key":"e_1_3_2_61_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00702-019-02084-y"},{"key":"e_1_3_2_62_1","doi-asserted-by":"publisher","DOI":"10.1038\/266730a0"},{"key":"e_1_3_2_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pnpbp.2021.110478"},{"key":"e_1_3_2_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0893-133X(01)00403-1"},{"key":"e_1_3_2_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.npep.2015.09.008"},{"key":"e_1_3_2_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuro.2020.06.011"},{"key":"e_1_3_2_67_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn1969"},{"key":"e_1_3_2_68_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1083328"},{"key":"e_1_3_2_69_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pnpbp.2021.110428"},{"key":"e_1_3_2_70_1","unstructured":"Sum CS Murphy BJ Li Z et al. (2004) Pharmacological characterization of GPCR agonists antagonists allosteric modulators and biased ligands from HTS hits to lead optimization. In: Assay Guidance Manual [Internet]. Bethesda (MD): Eli Lilly & Company and the National Center for Advancing Translational Sciences; 2004."},{"key":"e_1_3_2_71_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.REV120.009348"},{"key":"e_1_3_2_72_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-79242-w"},{"key":"e_1_3_2_73_1","doi-asserted-by":"publisher","DOI":"10.1002\/hipo.23474"},{"key":"e_1_3_2_74_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2017.00178"},{"key":"e_1_3_2_75_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.220232997"},{"key":"e_1_3_2_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2005.07.047"},{"key":"e_1_3_2_77_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2021.688655"},{"key":"e_1_3_2_78_1","first-page":"52587","article-title":"The forced swim test as a model of depressive-like behavior","volume":"97","author":"Yankelevitch-Yahav R","year":"2015","unstructured":"Yankelevitch-Yahav R, Franko M, Huly A, et al. (2015) The forced swim test as a model of depressive-like behavior. Journal of Visualized Experiments 97: 52587.","journal-title":"Journal of Visualized Experiments"},{"key":"e_1_3_2_79_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2019.00391"},{"key":"e_1_3_2_80_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.npep.2013.10.002"}],"container-title":["Journal of Psychopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02698811251389528","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/02698811251389528","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02698811251389528","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:12:33Z","timestamp":1777507953000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/02698811251389528"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,27]]},"references-count":79,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["10.1177\/02698811251389528"],"URL":"https:\/\/doi.org\/10.1177\/02698811251389528","relation":{},"ISSN":["0269-8811","1461-7285"],"issn-type":[{"value":"0269-8811","type":"print"},{"value":"1461-7285","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,27]]}}}