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Because language explicitly expresses these domains and voice implicitly conveys them, both may serve as potential \u2018biomarkers\u2019 of behavioural change.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>This study introduces a novel framework for analysing baseline language and vocal features, pre- to post-psychedelic changes, and assessing their potential to predict subjective experiences and psychological outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Daily voice journals from 29 participants were collected via \u201cRetreatBot\u201d for 2 weeks before and after 5-MeO-DMT (1 \u00d7 12 mg). Transcripts were analysed using natural language processing (bag-of-words for vocabulary; transformer model for textual affect), and acoustic features (e.g. pitch, jitter, shimmer) were extracted to assess vocal dynamics.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Following 5-MeO-DMT, speech markers revealed increased cognitive language, decreased social words, and altered voice quality (increased jitter\/shimmer). Baseline speech patterns predicted psychedelic preparedness, emotional breakthrough, and post-experience well-being.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>This first longitudinal analysis of speech markers surrounding a psychedelic retreat reveals a shift from external focus to introspection. Speech markers predicted and tracked psychological transformation surrounding the 5-MeO-DMT retreat experience, establishing vocal journaling as a valuable framework for monitoring changes during the \u201cpreparation\u201d and \u201cintegration\u201d periods.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/02698811261443690","type":"journal-article","created":{"date-parts":[[2026,5,23]],"date-time":"2026-05-23T08:14:25Z","timestamp":1779524065000},"page":"1321-1340","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Speech markers of psychological change following a psychedelic 5-MeO-DMT retreat"],"prefix":"10.1177","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4159-7176","authenticated-orcid":false,"given":"Joanna","family":"Kuc","sequence":"first","affiliation":[{"name":"Department of Experimental Psychology, University College London, UK"},{"name":"OneReach.AI, Denver, CO, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9435-0655","authenticated-orcid":false,"given":"Rosalind G.","family":"McAlpine","sequence":"additional","affiliation":[{"name":"Department of Experimental Psychology, University College London, UK"},{"name":"Clinical Psychopharmacology Unit, University College London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amelia","family":"Sellers","sequence":"additional","affiliation":[{"name":"Department of Experimental Psychology, University College London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6289-915X","authenticated-orcid":false,"given":"George","family":"Blackburne","sequence":"additional","affiliation":[{"name":"Department of Experimental Psychology, University College London, UK"},{"name":"Department of Computing, Imperial College London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1847-8451","authenticated-orcid":false,"given":"Daniel R.","family":"Lametti","sequence":"additional","affiliation":[{"name":"Department of Experimental Psychology, University College London, UK"},{"name":"OneReach.AI, Denver, CO, USA"},{"name":"Department of Psychology, Acadia University, Wolfville, NS, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5503-764X","authenticated-orcid":false,"given":"Jeremy I.","family":"Skipper","sequence":"additional","affiliation":[{"name":"Department of Experimental Psychology, University College London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,5,23]]},"reference":[{"key":"e_1_3_3_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/2167702617747074"},{"key":"e_1_3_3_3_1","doi-asserted-by":"publisher","DOI":"10.1037\/h0022773"},{"key":"e_1_3_3_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/soc13050117"},{"key":"e_1_3_3_5_1","unstructured":"AssemblyAI (2023) AssemblyAI Speech-to-Text API. 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