{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T12:16:55Z","timestamp":1763036215777,"version":"3.38.0"},"reference-count":40,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[1996,7,1]],"date-time":"1996-07-01T00:00:00Z","timestamp":836179200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Psychopharmacol"],"published-print":{"date-parts":[[1996,7]]},"abstract":"<jats:p> Nineteen patients with Tourette syndrome (TS) were treated with risperidone, at a mean daily dose of 1.5 mg. Of those, 41% responded positively, 35% felt that it had made no difference, while it made 24% worse. Although 53% of the patients experienced side-effects, none had extrapyramidal side-effects. At follow-up, 8 to 11 months later, only two of 19 (11 %) patients were still taking risperidone. We suggest that risperidone does have a role in a minority of TS sufferers but it is not suggested as the first line treatment. More placebo-controlled studies using risperidone are clearly indicated. <\/jats:p>","DOI":"10.1177\/026988119601000411","type":"journal-article","created":{"date-parts":[[2007,3,18]],"date-time":"2007-03-18T03:45:17Z","timestamp":1174189517000},"page":"317-320","source":"Crossref","is-referenced-by-count":30,"title":["Risperidone in the treatment of Tourette syndrome: a retrospective case note study"],"prefix":"10.1177","volume":"10","author":[{"given":"Mary M.","family":"Robertson","sequence":"first","affiliation":[{"name":"University College London Medical School, Middlesex Hospital Site, Mortimer Street, London W1N8AA, The National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David A.","family":"Scull","sequence":"additional","affiliation":[{"name":"Institute of Neurology, Queen Square, London WCIN 3BG, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valsamma","family":"Eapen","sequence":"additional","affiliation":[{"name":"University College London Medical School, Middlesex Hospital Site, Mortimer Street, London W1N8AA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael R.","family":"Trimble","sequence":"additional","affiliation":[{"name":"Institute of Neurology, Queen Square, London WCIN 3BG, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1996,7,1]]},"reference":[{"key":"atypb1","volume-title":"Diagnostic and statistical manual of mental disorders","author":"American Psychiatric Association","year":"1987","edition":"3"},{"key":"atypb2","volume-title":"Diagnostic and statistical manual of mental disorders","author":"American Psychiatric Association","year":"1994","edition":"4"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1177\/026988119500900311"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1989.01810010025004"},{"key":"atypb5","first-page":"213","volume":"28","author":"Borison R.L.","year":"1992","journal-title":"Psychopharmacol Bull"},{"issue":"3","key":"atypb6","first-page":"115","volume":"10","author":"Bruggeman R.","year":"1994","journal-title":"Neuropsychopharmacology"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1097\/00004714-199302000-00004"},{"key":"atypb8","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1002\/hup.470090511","volume":"9","author":"Cosgrove F.","year":"1994","journal-title":"Hum Psychopharmacol"},{"key":"atypb9","first-page":"181","volume":"29","author":"Desai A.B.","year":"1983","journal-title":"J Postgrad Med"},{"key":"atypb10","first-page":"229P","volume":"102","author":"Dursun S.M.","year":"1991","journal-title":"Br J Pharmacol"},{"journal-title":"J Psychopharmacol","year":"1992","author":"Dursun S.M.","key":"atypb11"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.1177\/026988119400800105"},{"key":"atypb13","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.165.2.267"},{"key":"atypb14","first-page":"622P","volume":"112","author":"Dursun S.M.","year":"1994","journal-title":"Br J Pharmacol"},{"key":"atypb15","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(94)90388-3"},{"key":"atypb16","doi-asserted-by":"publisher","DOI":"10.1016\/0278-5846(96)00044-9"},{"key":"atypb17","doi-asserted-by":"publisher","DOI":"10.1007\/BF00449911"},{"key":"atypb18","doi-asserted-by":"publisher","DOI":"10.1002\/hup.470080505"},{"key":"atypb19","doi-asserted-by":"publisher","DOI":"10.1177\/026988119300700411"},{"key":"atypb20","first-page":"423","volume":"56","author":"Jacobsen F.M.","year":"1995","journal-title":"J Clin Psychiatr"},{"key":"atypb21","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.35.3.343"},{"key":"atypb22","unstructured":"Leckman J.F., Towbin K.E., Ort S.I., Cohen D.J. (1988) Clinical assessment of tic disorder severity. In Cohen D J, Bruun R D, Leckman J F (eds), Tourette's syndrome and tic disorders. Wiley, New York, pp. 55-78"},{"key":"atypb23","doi-asserted-by":"publisher","DOI":"10.1097\/00004583-198907000-00015"},{"key":"atypb24","first-page":"494","volume":"41","author":"Leysen J.E.","year":"1992","journal-title":"Molec Pharmacol"},{"key":"atypb25","doi-asserted-by":"publisher","DOI":"10.1097\/00004583-199509000-00011"},{"journal-title":"Psychopharmacology","year":"1994","author":"Reveley M.A.","key":"atypb26"},{"key":"atypb27","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.154.2.147"},{"key":"atypb28","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7610.1994.tb01209.x"},{"key":"atypb29","first-page":"49","author":"Robertson M.M.","year":"1995","journal-title":"J Serotonin Res"},{"key":"atypb30","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.156.4.515"},{"key":"atypb31","doi-asserted-by":"publisher","DOI":"10.1097\/00002826-199210000-00010"},{"key":"atypb32","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1234-988X(199612)6:4<203::AID-MPR165>3.3.CO;2-F"},{"key":"atypb33","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.152.3.383"},{"key":"atypb34","doi-asserted-by":"publisher","DOI":"10.1097\/00002826-199006000-00005"},{"key":"atypb35","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.162.1.114"},{"key":"atypb36","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1989.01810080052006"},{"key":"atypb37","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(93)91392-Y"},{"key":"atypb38","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(94)90389-1"},{"key":"atypb39","doi-asserted-by":"publisher","DOI":"10.1002\/mds.870090617"},{"volume-title":"International classification of diseases and health related problems (10th revision)","year":"1992","key":"atypb40"}],"container-title":["Journal of Psychopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/026988119601000411","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/026988119601000411","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,2]],"date-time":"2025-03-02T20:13:45Z","timestamp":1740946425000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/026988119601000411"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,7]]},"references-count":40,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1996,7]]}},"alternative-id":["10.1177\/026988119601000411"],"URL":"https:\/\/doi.org\/10.1177\/026988119601000411","relation":{},"ISSN":["0269-8811","1461-7285"],"issn-type":[{"type":"print","value":"0269-8811"},{"type":"electronic","value":"1461-7285"}],"subject":[],"published":{"date-parts":[[1996,7]]}}}