{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T05:35:09Z","timestamp":1741066509934,"version":"3.38.0"},"reference-count":32,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[1997,7,1]],"date-time":"1997-07-01T00:00:00Z","timestamp":867715200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Psychopharmacol"],"published-print":{"date-parts":[[1997,7]]},"abstract":"<jats:p> We have measured \u03b2-adrenoceptor binding in pineal glands obtained at post mortem from suicides with a firm retrospective diagnosis of depression, and from age and gender-matched controls. In both antidepressant-free and antidepressant-treated suicides there were no significant differences in the number or affinity of \u03b2- adrenoceptors compared to controls. Within the total group of subjects we found no variation in \u03b2- adrenoceptor binding in relation to time of death or season of death. There was a significant negative correlation between the number of \u03b2-adrenoceptors and age in controls, but not in suicides. These results suggest that pineal \u03b2-adrenoceptors are not altered either in depression or as a result of antidepressant treatment. <\/jats:p>","DOI":"10.1177\/026988119701100403","type":"journal-article","created":{"date-parts":[[2008,6,2]],"date-time":"2008-06-02T21:43:24Z","timestamp":1212443004000},"page":"295-299","source":"Crossref","is-referenced-by-count":4,"title":["\u03b2-Adrenoceptors in human pineal glands are unaltered in depressed suicides"],"prefix":"10.1177","volume":"11","author":[{"given":"Freddy","family":"De Paermentier","sequence":"first","affiliation":[{"name":"Departments of Pharmacology and Clinical Pharmacology"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra","family":"Lowther","sequence":"additional","affiliation":[{"name":"Departments of Pharmacology and Clinical Pharmacology"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. 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