{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T15:30:31Z","timestamp":1792510231868,"version":"4.5.0"},"reference-count":24,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2015,10,13]],"date-time":"2015-10-13T00:00:00Z","timestamp":1444694400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Cereb Blood Flow Metab"],"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:p>\n                    The purposes of this study are to establish oxygen extraction fraction (OEF) measurements using quantitative susceptibility mapping (QSM) of magnetic resonance imaging (MRI), and to compare QSM\u2013OEF data with the gold standard\n                    <jats:sup>15<\/jats:sup>\n                    O positron emission tomography (PET). Twenty-six patients with chronic unilateral internal carotid artery or middle cerebral artery stenosis or occlusion, and 15 normal subjects were included. MRI scans were conducted using a 3.0 Tesla scanner with a three-dimensional spoiled gradient recalled sequence. QSM images were created using the morphology-enabled dipole inversion method, and OEF maps were generated from QSM images using extraction of venous susceptibility induced by deoxygenated hemoglobin. Significant correlation of relative OEF ratio to contra-lateral hemisphere between QSM\u2013OEF and PET\u2013OEF was observed (r\u2009=\u20090.62, p\u2009&lt;\u20090.001). The local (intra-section) correlation was also significant (r\u2009=\u20090.52, p\u2009&lt;\u20090.001) in patients with increased PET\u2013OEF. The sensitivity and specificity of OEF increase in QSM was 0.63 (5\/8) and 0.89 (16\/18), respectively, in comparison with PET. In conclusion, good correlation was achieved between QSM\u2013OEF and PET\u2013OEF in the identification of elevated OEF in affected hemispheres of patients with unilateral chronic steno-occlusive disease.\n                  <\/jats:p>","DOI":"10.1177\/0271678x15606713","type":"journal-article","created":{"date-parts":[[2015,12,4]],"date-time":"2015-12-04T13:43:48Z","timestamp":1449236628000},"page":"1424-1433","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":101,"title":["Oxygen extraction fraction measurement using quantitative susceptibility mapping: Comparison with positron emission tomography"],"prefix":"10.1177","volume":"36","author":[{"given":"Kohsuke","family":"Kudo","sequence":"first","affiliation":[{"name":"Division of Ultra-High Field MRI, Iwate Medical University, Japan"},{"name":"Department of Diagnostic and Interventional Radiology, Hokkaido University Hospital, 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