{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T13:16:28Z","timestamp":1782738988105,"version":"3.54.5"},"reference-count":30,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2017,8,8]],"date-time":"2017-08-08T00:00:00Z","timestamp":1502150400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Cereb Blood Flow Metab"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:p>The purpose was to assess the difference of collaterals in symptomatic versus asymptomatic patients with unilateral middle cerebral artery (MCA) stenosis by comparing cerebral blood flow (CBF) at two post labeling delays (PLD) using three-dimensional pseudo-continuous arterial spin labeling (3D pCASL). Eighty-one patients (49 symptomatic and 32 asymptomatic) with unilateral MCA stenosis \u226550% who underwent pCASL with two PLDs were included. Mean CBF and CBF subtraction images between two PLDs of MCA territories were compared in symptomatic and asymptomatic groups, respectively. Compared with the asymptomatic group, patients with symptomatic MCA stenosis had significantly lower CBF in the MCA territory of stenotic side at each PLD. The CBF of stenotic territory showed greater increase than that of normal side from PLD 1.5 to 2.5\u2009s. The CBF of asymptomatic MCA territory increased similarly with that of symptomatic MCA territory from PLD of 1.5 to 2.5\u2009s in stenotic side, while symptomatic patients experienced significantly slower antegrade flow. On CBF subtraction images, asymptomatic patients showed larger volume of differences between PLD of 1.5 and 2.5\u2009s compared with those of symptomatic patients ( p\u2009=\u20090.037). The results suggest that more robust collateral perfusion on two-delay 3D pCASL is present in asymptomatic patients compared with symptomatic patients.<\/jats:p>","DOI":"10.1177\/0271678x17725212","type":"journal-article","created":{"date-parts":[[2017,8,8]],"date-time":"2017-08-08T10:43:31Z","timestamp":1502189011000},"page":"108-117","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":41,"title":["Collateral perfusion using arterial spin labeling in symptomatic versus asymptomatic middle cerebral artery stenosis"],"prefix":"10.1177","volume":"39","author":[{"given":"Xin","family":"Lou","sequence":"first","affiliation":[{"name":"Department of Radiology and Department of Neurology, Chinese People's Liberation Army (PLA), General Hospital, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoxiao","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Radiology and Department of Neurology, Chinese People's Liberation Army (PLA), General Hospital, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David S","family":"Liebeskind","sequence":"additional","affiliation":[{"name":"Department of Neurology, University of California Los Angeles, Los Angeles, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ning","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Interventional Neuroradiology, Beijing Tiantan Hospital, Capital Medical University, China National Clinical Research Center for NeurologicalDiseases, Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenglin","family":"Tian","sequence":"additional","affiliation":[{"name":"Department of Radiology and Department of Neurology, Chinese People's Liberation Army (PLA), General Hospital, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinhao","family":"Lyu","sequence":"additional","affiliation":[{"name":"Department of Radiology and Department of Neurology, Chinese People's Liberation Army (PLA), General Hospital, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaojing","family":"Long","sequence":"additional","affiliation":[{"name":"Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Radiology and Department of Neurology, Chinese People's Liberation Army (PLA), General Hospital, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danny JJ","family":"Wang","sequence":"additional","affiliation":[{"name":"Laboratory of FMRI Technology (LOFT), Mark & Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2017,8,8]]},"reference":[{"key":"bibr1-0271678X17725212","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.113.004072"},{"key":"bibr2-0271678X17725212","doi-asserted-by":"publisher","DOI":"10.1007\/s00234-002-0881-0"},{"key":"bibr3-0271678X17725212","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2007.132100"},{"key":"bibr4-0271678X17725212","doi-asserted-by":"publisher","DOI":"10.1038\/jcbfm.2010.224"},{"key":"bibr5-0271678X17725212","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.107.499475"},{"key":"bibr6-0271678X17725212","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000175983.76110.59"},{"key":"bibr7-0271678X17725212","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A3491"},{"key":"bibr8-0271678X17725212","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.24175"},{"key":"bibr9-0271678X17725212","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.25197"},{"key":"bibr10-0271678X17725212","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.111.616466"},{"key":"bibr11-0271678X17725212","doi-asserted-by":"publisher","DOI":"10.1016\/j.nicl.2013.06.017"},{"key":"bibr12-0271678X17725212","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.111.631929"},{"key":"bibr13-0271678X17725212","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.115.011057"},{"key":"bibr14-0271678X17725212","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.13898"},{"key":"bibr15-0271678X17725212","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.50.6.1699"},{"key":"bibr16-0271678X17725212","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.27.6.1084"},{"key":"bibr17-0271678X17725212","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000126043.83777.3a"},{"key":"bibr18-0271678X17725212","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A2794"},{"key":"bibr19-0271678X17725212","doi-asserted-by":"publisher","DOI":"10.1002\/ana.21130"},{"key":"bibr20-0271678X17725212","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A1408"},{"key":"bibr21-0271678X17725212","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-013-3024-6"},{"key":"bibr22-0271678X17725212","doi-asserted-by":"publisher","DOI":"10.1038\/jcbfm.2014.182"},{"key":"bibr23-0271678X17725212","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000173036.95976.46"},{"key":"bibr24-0271678X17725212","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000345360.80382.69"},{"key":"bibr25-0271678X17725212","doi-asserted-by":"publisher","DOI":"10.1111\/j.1552-6569.2012.00784.x"},{"key":"bibr26-0271678X17725212","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(11)70195-8"},{"key":"bibr27-0271678X17725212","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A2697"},{"key":"bibr28-0271678X17725212","doi-asserted-by":"publisher","DOI":"10.1097\/RMR.0b013e31821e570a"},{"key":"bibr29-0271678X17725212","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A1259"},{"key":"bibr30-0271678X17725212","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.108.520593"}],"container-title":["Journal of Cerebral Blood Flow &amp; Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0271678X17725212","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0271678X17725212","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0271678X17725212","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T20:14:57Z","timestamp":1777493697000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0271678X17725212"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8,8]]},"references-count":30,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,1]]}},"alternative-id":["10.1177\/0271678X17725212"],"URL":"https:\/\/doi.org\/10.1177\/0271678x17725212","relation":{},"ISSN":["0271-678X","1559-7016"],"issn-type":[{"value":"0271-678X","type":"print"},{"value":"1559-7016","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,8,8]]}}}