{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T19:20:45Z","timestamp":1789154445033,"version":"build-2803163510"},"reference-count":10,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2021,6,29]],"date-time":"2021-06-29T00:00:00Z","timestamp":1624924800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Cereb Blood Flow Metab"],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:p>The last 50\u2009years have witnessed the translation of stem cell therapy from the laboratory to the clinic for treating brain disorders, in particular stroke. From the focal stereotaxic transplantation to the minimally invasive intravenous and intraarterial delivery, stem cells display the ability to replenish injured cells and to secrete therapeutic molecules, altogether promoting brain repair. The increased stroke incidence in COVID-19 survivors poses as a new disease indication for cell therapy, owing in part to the cells\u2019 robust anti-inflammatory properties. Optimization of the cell transplant regimen will ensure the safe and effective clinical application of cell therapy in stroke and relevant neurological disorders.<\/jats:p>","DOI":"10.1177\/0271678x211026507","type":"journal-article","created":{"date-parts":[[2021,6,30]],"date-time":"2021-06-30T02:39:26Z","timestamp":1625020766000},"page":"2797-2799","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":11,"title":["Recent advances in cell therapy for stroke"],"prefix":"10.1177","volume":"41","author":[{"given":"You Jeong","family":"Park","sequence":"first","affiliation":[{"name":"Department of Neurosurgery and Brain Repair, University of South Florida Morsani College of Medicine, Tampa, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2966-9782","authenticated-orcid":false,"given":"Cesar V","family":"Borlongan","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery and Brain Repair, University of South Florida Morsani College of Medicine, Tampa, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,6,29]]},"reference":[{"key":"bibr1-0271678X211026507","doi-asserted-by":"publisher","DOI":"10.1006\/exnr.1997.6730"},{"key":"bibr2-0271678X211026507","doi-asserted-by":"publisher","DOI":"10.1126\/science.2105529"},{"key":"bibr3-0271678X211026507","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.55.4.565"},{"key":"bibr4-0271678X211026507","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(99)90229-5"},{"key":"bibr5-0271678X211026507","doi-asserted-by":"publisher","DOI":"10.1177\/0271678X20972656"},{"key":"bibr6-0271678X211026507","doi-asserted-by":"publisher","DOI":"10.1177\/0271678X19900037"},{"key":"bibr7-0271678X211026507","doi-asserted-by":"publisher","DOI":"10.1177\/0271678X18811277"},{"key":"bibr8-0271678X211026507","doi-asserted-by":"crossref","unstructured":"Rauch A, Mandrup S. 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