{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T13:36:43Z","timestamp":1789393003421,"version":"build-2803163510"},"reference-count":10,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2023,5,27]],"date-time":"2023-05-27T00:00:00Z","timestamp":1685145600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Cereb Blood Flow Metab"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:p>We discuss the current evidence for both benefit and harm of antihypertensive treatment in people with dementia. We conclude that there is a lack of evidence to support the claim that there is an increased risk of cerebral hypoperfusion with antihypertensive treatment in dementia, and that there is growing evidence which refutes this claim.<\/jats:p>","DOI":"10.1177\/0271678x231179421","type":"journal-article","created":{"date-parts":[[2023,5,27]],"date-time":"2023-05-27T06:41:44Z","timestamp":1685169704000},"page":"1796-1799","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Antihypertensives in dementia: Good or bad for the brain?"],"prefix":"10.1177","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2740-6487","authenticated-orcid":false,"given":"Rachel AM","family":"Heutz","sequence":"first","affiliation":[{"name":"Department of Geriatric Medicine, Radboudumc Alzheimer Center, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4150-7345","authenticated-orcid":false,"given":"Ralf WJ","family":"Weijs","sequence":"additional","affiliation":[{"name":"Department of Geriatric Medicine, Radboudumc Alzheimer Center, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands"},{"name":"Department of Medical BioSciences, Radboud University Medical Center, Nijmegen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rianne AA","family":"de Heus","sequence":"additional","affiliation":[{"name":"Department of Geriatric Medicine, Radboudumc Alzheimer Center, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands"},{"name":"Department of Primary and Community Care, Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jurgen AHR","family":"Claassen","sequence":"additional","affiliation":[{"name":"Department of Geriatric Medicine, Radboudumc Alzheimer Center, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands"},{"name":"Department of Cardiovascular Sciences, University of Leicester, Leicester, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,5,27]]},"reference":[{"key":"bibr1-0271678X231179421","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00022.2020"},{"key":"bibr2-0271678X231179421","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2022.1657"},{"key":"bibr3-0271678X231179421","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2018.21442"},{"key":"bibr4-0271678X231179421","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2111437"},{"key":"bibr5-0271678X231179421","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.118.10900"},{"key":"bibr6-0271678X231179421","doi-asserted-by":"publisher","DOI":"10.1002\/alz.12666"},{"key":"bibr7-0271678X231179421","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.121.18255"},{"key":"bibr8-0271678X231179421","doi-asserted-by":"publisher","DOI":"10.1016\/j.cccb.2021.100024"},{"key":"bibr9-0271678X231179421","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehac584"},{"key":"bibr10-0271678X231179421","doi-asserted-by":"publisher","DOI":"10.7326\/M20-4298"}],"container-title":["Journal of Cerebral Blood Flow &amp; Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0271678X231179421","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0271678X231179421","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0271678X231179421","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T20:14:33Z","timestamp":1777493673000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0271678X231179421"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,27]]},"references-count":10,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2023,10]]}},"alternative-id":["10.1177\/0271678X231179421"],"URL":"https:\/\/doi.org\/10.1177\/0271678x231179421","relation":{},"ISSN":["0271-678X","1559-7016"],"issn-type":[{"value":"0271-678X","type":"print"},{"value":"1559-7016","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5,27]]}}}