{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T16:43:08Z","timestamp":1778085788956,"version":"3.51.4"},"reference-count":40,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2024,8,20]],"date-time":"2024-08-20T00:00:00Z","timestamp":1724112000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Cereb Blood Flow Metab"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:p>\n                    Cerebral blood flow (CBF) and oxygen extraction fraction (OEF) can be measured using arterial spin labeling (ASL) and quantitative susceptibility mapping (QSM) sequences, respectively. ASL and QSM sequences were performed on 13 healthy participants and 46 patients with unilateral or bilateral Middle cerebral artery (MCA) occlusion. M1\u2013M3 and M4\u2013M6 correspond to anterior, lateral, and posterior MCA territories within the insular ribbon and centrum semiovale, respectively. In patients with unilateral MCA occlusion, significant decreases in CBF were observed in the lesions in M1, M3, M5 and M6 regions, as well as in the contralateral M3 and M5 regions. The OEF of the lesion in the M1\u2013M4 and M6 regions, and the contralateral M1\u2013M3 regions were significantly higher. Additionally, the cerebral metabolic rate of oxygen (CMRO\n                    <jats:sub>2<\/jats:sub>\n                    ) in the lesions of the M3 and M6 regions, and the contralateral M3 region, were significantly lower compared to the corresponding regions of healthy participants. For patients with bilateral MCA occlusion, the CMRO\n                    <jats:sub>2<\/jats:sub>\n                    in the left M5 region and the right M3 and M6 regions were significantly lower than that in the corresponding regions of healthy participants. In conclusion, abnormal hemodynamics occur in the contralateral hemisphere of patients with unilateral MCA occlusion.\n                  <\/jats:p>","DOI":"10.1177\/0271678x241276386","type":"journal-article","created":{"date-parts":[[2024,8,20]],"date-time":"2024-08-20T03:18:20Z","timestamp":1724123900000},"page":"319-327","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Oxygen extraction fraction change in M1-M6 brain regions of patients with unilateral or bilateral middle cerebral artery occlusion"],"prefix":"10.1177","volume":"45","author":[{"given":"Yu","family":"Xiao","sequence":"first","affiliation":[{"name":"Department of Radiology, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University; Intelligent Medical Imaging of Jiangxi Key Laboratory, Nanchang city, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8848-4905","authenticated-orcid":false,"given":"Zhenghua","family":"Liu","sequence":"additional","affiliation":[{"name":"The Department of Radiology, The Dongguan Maternal and Child Health Care Hospital, Guangdong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinghua","family":"Wan","sequence":"additional","affiliation":[{"name":"The Department of Radiology, The People\u2019s Hospital of Nanchang County, Nanchang city, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,8,20]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2022.0048"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A4624"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.12120928"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.111.631929"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.24918"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.27135"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2018.09.035"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.29300"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.29272"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/nbm.3569"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.1148\/rg.210054"},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.25463"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.117.017166"},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.1177\/0271678X15606713"},{"key":"e_1_3_4_16_2","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2021.736891"},{"key":"e_1_3_4_17_2","doi-asserted-by":"publisher","DOI":"10.1177\/0271678X18764829"},{"key":"e_1_3_4_18_2","doi-asserted-by":"publisher","DOI":"10.1177\/0271678X211048031"},{"key":"e_1_3_4_19_2","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2022.896006"},{"key":"e_1_3_4_20_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.118.023426"},{"key":"e_1_3_4_21_2","doi-asserted-by":"publisher","DOI":"10.1177\/0271678X19827944"},{"key":"e_1_3_4_22_2","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2022.752450"},{"key":"e_1_3_4_23_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.25358"},{"key":"e_1_3_4_24_2","doi-asserted-by":"publisher","DOI":"10.2144\/000112517"},{"key":"e_1_3_4_25_2","doi-asserted-by":"publisher","DOI":"10.1111\/cpf.12288"},{"key":"e_1_3_4_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)02237-6"},{"key":"e_1_3_4_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2015.11.007"},{"key":"e_1_3_4_28_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.26657"},{"key":"e_1_3_4_29_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.27967"},{"key":"e_1_3_4_30_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.28390"},{"key":"e_1_3_4_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2020.109490"},{"key":"e_1_3_4_32_2","doi-asserted-by":"publisher","DOI":"10.1177\/0271678X17700913"},{"key":"e_1_3_4_33_2","doi-asserted-by":"publisher","DOI":"10.1177\/0271678X18805209"},{"key":"e_1_3_4_34_2","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2021.660529"},{"key":"e_1_3_4_35_2","doi-asserted-by":"publisher","DOI":"10.1038\/jcbfm.2012.171"},{"key":"e_1_3_4_36_2","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A7167"},{"key":"e_1_3_4_37_2","doi-asserted-by":"publisher","DOI":"10.1097\/WCO.0000000000000051"},{"key":"e_1_3_4_38_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10334-021-00964-7"},{"key":"e_1_3_4_39_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00429-019-01919-4"},{"key":"e_1_3_4_40_2","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.24337"},{"key":"e_1_3_4_41_2","doi-asserted-by":"crossref","unstructured":"Bazin PL Plessis V Fan AP et\u00a0al. 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